There are currently 134 active clinical trials seeking participants for Autism Spectrum Disorder research studies. The states with the highest number of trials for Autism Spectrum Disorder participants are California, New York, Ohio and Florida.
Transcranial Magnetic Stimulation (TMS) Study for Adults With Autism Spectrum Disorder (ASD)
Recruiting
This is a randomized interventional study designed to evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS) on neural and behavioral facets of social cognition in adults with autism spectrum disorder (ASD).
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/25/2025
Locations: Yale University Child Study Center, New Haven, Connecticut
Conditions: Autism Spectrum Disorder
Emergent Multi-Class Imitation Training
Recruiting
The goals of this project are to (a) incorporate empirical findings on imitation training and learning in autistic children into a comprehensive protocol for Applied Behavior Analysis practitioners designed to rapidly facilitate generalized imitation called Emergent Multi-Class Imitation Training (EMIT), and (b) collect pilot data on the efficacy of EMIT with a small sample of autistic children. EMIT will incorporate several features that are grounded in prior research including: (a) evidence-ba... Read More
Gender:
ALL
Ages:
Between 12 months and 6 years
Trial Updated:
07/23/2025
Locations: Rutgers University, New Brunswick, New Jersey
Conditions: Autism Spectrum Disorder
Transcranial Direct Current Stimulation in Children With Autism
Recruiting
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who show an absence or a plateau in various skills. Deficits in executive functioning are likely to be involved in many of these cognitive and learning disabilities due to poor functioning of the prefrontal cortex. Currently, the use of biological methods for improving learnin... Read More
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
07/22/2025
Locations: New York State Institute for Basic Research, Staten Island, New York
Conditions: Autism Spectrum Disorder, Executive Dysfunction
Safety and Efficacy of tPBM for Epileptiform Activity in Autism
Recruiting
For this study, the proposed intervention will be noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM) - to the brains of autistic children. This will occur, twice a week, for 10 weeks. The NIR light is delivered to specific brain areas by Cognilum, a wearable device developed by Jelikalite. The expected outcome is improved focus, improved eye contact, improved speech, improved behavior, and gains in functional skills. Cognilum may impact the clinical pract... Read More
Gender:
ALL
Ages:
Between 4 years and 12 years
Trial Updated:
07/21/2025
Locations: Rossignol Medical Center, Phoenix, Arizona
Conditions: Autism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental Disorders, Neurological Disorder
Resources for Optimizing Outcomes in Toddlers on the Spectrum
Recruiting
The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for toddlers under the age of 4 living in Rural NC after their initial diagnosis of autism. The main questions it aims to answer are: Does Family Navigation decrease the time to initiation of intervention for rural toddlers with autism? Does Family Navigation improve developmental outcomes at 18 months post-diagno... Read More
Gender:
ALL
Ages:
Between 1 year and 99 years
Trial Updated:
07/18/2025
Locations: Carolina Institute for Developmental Disabilities, Carrboro, North Carolina
Conditions: Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Recruiting
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting. The purpose of this study is to determine the feasibility of implementing this treatment in community care centers.
Gender:
ALL
Ages:
Between 7 years and 17 years
Trial Updated:
07/18/2025
Locations: Johns Hopkins University, Baltimore, Maryland +2 locations
Conditions: Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder, Social Anxiety Disorder of Childhood
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Recruiting
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost, practicalities of attending in-person treatment sessions, and a shortage of trained providers, especially in rural areas. The goal of this project is to increase access to care for families of autistic adolescents with anxiety through an internet-based treatment model.
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
07/18/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder
Autism Research Project With Non-Invasive Near-Infrared Light Stimulation
Recruiting
The investigators have previously shown that the administration of low-level infrared light is a safe and non-invasive procedure which improves cognition and emotion, as well as enhances brain metabolic activity. Based on previous studies, the investigators hypothesize that this methodology, called low-level light therapy or photobiomodulation, could be used to improve behavioral symptoms in individuals with autism spectrum disorder (ASD).
Gender:
ALL
Ages:
Between 4 years and 60 years
Trial Updated:
07/15/2025
Locations: Seay Psychology Building, Room 3.304, Austin, Texas
Conditions: Autism Spectrum Disorder
Application of Virtual Reality Technology to Treatment of Social Anxiety
Recruiting
The purpose of this study is to compare CBT VR exposure + VR social skills treatment to CBT Imaginal exposure + mindfulness, in reducing the severity of social anxiety in adults with autism and social anxiety (SA), to identify characteristics associated with benefitting from the CBT-VR treatment and to assess acceptability and feasibility of the VR intervention for patients receiving it and use findings to improve methods and to prepare for a community based pragmatic trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2025
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Autism Spectrum Disorder, Social Anxiety Disorder
Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
Recruiting
The primary objective of this research study is to improve outcomes involving core social-communication symptoms for young children with ASD or social communication delays by increasing access to clinically validated early behavioral intervention through a telehealth parent coaching model. The investigators will test the hypothesis that telehealth-delivered Naturalistic Developmental Behavioral Intervention parent coaching (TC) is non-inferior to in-person coaching (IPC) for the treatment of cor... Read More
Gender:
ALL
Ages:
Between 18 months and 42 months
Trial Updated:
07/10/2025
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Autism Spectrum Disorder, Autistic Disorder, Active Autistic Disorder, Autism, Asperger Syndrome, PDD-NOS, Social Communication Delay, Mixed Expressive Receptive Language Disorder, Other Symbolic Dysfunctions
Family-school Partnership Intervention for Early Childhood Education
Recruiting
Strategies for creating and maintaining reciprocal partnerships between teachers and parents are considered essential elements of developmentally appropriate practice in early childhood education (ECE). Particularly for children who are high-risk for behavioral, developmental, or mental health problems, effective partnerships between family and preschool are essential for promoting optimal classroom participation and learning outcomes. The current study is an uncontrolled (pre-post) feasibility... Read More
Gender:
ALL
Ages:
Between 2 years and 6 years
Trial Updated:
07/08/2025
Locations: UNT, Denton, Texas
Conditions: Autism Spectrum Disorder
Pediatric Patients With Metabolic or Other Genetic Disorders
Recruiting
Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be eligible to join current research studies. Testing such patients is a good way to improve the skills of research staff. The findings could lead to new processes and research. Objectives: To recruit a diverse group of pediatric subjects with genetic disorders. To give clinic staff hands-on experience working with these patients. Eligibility: Children any age with... Read More
Gender:
ALL
Ages:
Between 1 year and 99 years
Trial Updated:
07/07/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome, Developmental Delay