There are currently 158 active clinical trials seeking participants for Chronic Pain research studies. The states with the highest number of trials for Chronic Pain participants are California, Florida, Texas and New York.
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
Recruiting
The present study seeks to examine the implementation process of culturally tailoring screening and brief intervention for both chronic pain and opioid misuse/opioid use disorder in three American Indian and Alaska Native (AI/AN) serving clinics. The investigators also will assess staff perspectives on this implementation as well as a survey to understand clients at these sites who have chronic pain and opioid misuse/opioid use disorder.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/30/2024
Locations: Clinic Site A (blinded pending tribal approval), Arcata, California +2 locations
Conditions: Opioid Use Disorder, Opioid Misuse, Chronic Pain
Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure
Recruiting
This project is a single-site, randomized controlled trial designed to investigate the impact of a 7-minute mindfulness intervention on pain among patients undergoing kyphoplasty or radiofrequency ablation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/30/2024
Locations: Tallahassee Orthopedic Clinic (TOC), Tallahassee, Florida
Conditions: Pain, Chronic Pain, Acute Pain
Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain
Recruiting
This protocol aims to test whether an infusion of allogeneic bone marrow-derived mesenchymal stromal cells (BM-MSCs) can reduce pain associated with chronic pancreatitis (CP) and explore potential mechanisms of MSC action.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/28/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Chronic Pancreatitis, Chronic Pain
Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain
Recruiting
Pain has been identified as among the most frequent presenting medical complaints, in particular within primary care for Veterans. There are few areas of daily living and functioning that pain intensity does not impact, with reported pain intensity related to difficulties in social situations and changes in activities of daily life, sleep, and appetite. Therapeutic interventions such as Acceptance and Commitment Therapy for Chronic Pain (ACT-CP) that target issues related to the cognitions and e... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/28/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut +2 locations
Conditions: Chronic Pain
Utilizing Battlefield Acupuncture to Treat Chronic Pain
Recruiting
This research study will evaluate the effectiveness of utilizing Battlefield Acupuncture (BFA) on veterans with with a history of substance use disorder and chronic pain for 8 weeks. Primary Aim: The primary aim of this study is to evaluate the effectiveness of using BFA to treat chronic pain in veterans with a history of substance use disorder. Secondary Aim: This study will also evaluate the impact that BFA treatment for pain may have on subjects' stress, mood and sleep patterns over 8 weeks... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: Bedford VA Healthcare System, Bedford, Massachusetts
Conditions: Chronic Pain, Substance Use Disorders
NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
Recruiting
This study is a double-blind, randomized controlled trial comparing the effectiveness of oral acetaminophen, diclofenac, and tramadol in reducing the consumption of narcotic doses (primary outcome) and minimizing patients' exposure to narcotics (secondary outcome) following an ultrasound-guided percutaneous needle tenotomy procedure on the lateral elbow.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/20/2024
Locations: The Cleveland Clinic Florida, Coral Springs, Florida +1 locations
Conditions: Elbow Pain, Chronic Pain
Overlapping Pain Trajectory Study
Recruiting
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
08/20/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UG3 Pilot
Recruiting
This project addresses the significant challenge of providing evidence-based non-pharmacologic pain management to rural-dwelling Veterans in the VA healthcare system who have chronic pain. For this preparatory phase (UG3) the investigators will conduct a pilot study of 40 rural VA patients with chronic pain to assess the feasibility of delivering RAMP (experimental intervention for the UH3 trial) in terms of recruitment and engagement, intervention fidelity and adherence, data collection, and ot... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Minneapolis VAMC, Minneapolis, Minnesota
Conditions: Chronic Pain
Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
Recruiting
The REALITY study is a prospective, post-market, non-randomized, multi-center, single-arm, open-label study intended to collect short- and long-term safety and effectiveness data on various populations implanted with Abbott's neurostimulation systems.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Phoenician Centers for Research & Innovation, Phoenix, Arizona +54 locations
Conditions: Chronic Pain
Local Cerebral Oxygenation in Chronic Pain Patients Utilizing Spinal Cord Stimulation
Recruiting
The primary objective of the study is to determine changes in cerebral nociceptive hemodynamic response (blood oxygenation/flow) before, during and following spinal cord stimulation (SCS). Objective measurements of cerebral nociceptive hemodynamic responses will be obtained with the CereVu sensor and ROPA system and will be analyzed offline and compared against subjective measures of pain. Proprietary analysis algorithms will be incorporated and developed to understand how the objective measurem... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2024
Locations: Boomerang Healthcare, Walnut Creek, California
Conditions: Chronic Pain
Palmitoylethanolamide for Chronic Inflammatory Pain Conditions
Recruiting
The goal of this clinical trial is to evaluate if a supplement called palmitoylethanolamide (PEA) is effective in reducing the pain in patients with chronic inflammatory pain conditions. The main question the trial aims to answer is if PEA works better at treating a patients pain and improving their function better than a placebo. Participants will be divided into two equal groups and asked to take either PEA or a placebo for 8 weeks.
Gender:
ALL
Ages:
All
Trial Updated:
08/13/2024
Locations: Naval Medical Center San Diego, San Diego, California
Conditions: Chronic Pain
Mobile App-based Approach for Reducing Pain and Hazardous Drinking: a Pilot Study
Recruiting
Chronic pain and heavy drinking are common co-occurring conditions among patients presenting to primary care settings. Given their impact on functioning and medical outcomes, there would be considerable benefit to developing an accessible, easily utilized, integrative approach to reduce alcohol use and pain that can be readily incorporated into the health care settings. The objective of this study is to test a modified version of a smartphone-based intervention for reducing pain and alcohol use... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2024
Locations: Boston University, Boston, Massachusetts
Conditions: Alcohol Drinking, Chronic Pain