There are currently 151 active clinical trials seeking participants for Chronic Pain research studies. The states with the highest number of trials for Chronic Pain participants are California, Florida, Texas and New York.
Overlapping Pain Trajectory Study
NCT05752396
Recruiting
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition to COP... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
01/30/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
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Impact of 4PCP on Practitioner and Patient Outcomes
NCT05580419
Recruiting
Reducing opioid prescribing and improving outcomes in patients with chronic pain would benefit our nation. Neither addiction nor chronic pain spares any race, gender, or particular socio-economic status. This study is investigating a potentially inexpensive way of providing a previously costly service (the intensive chronic pain rehabilitation program), which is why insurers stopped covering it. Although it is unusual for an application from an academic institution to include a startup company (... Read More
Gender:
All
Ages:
Between 14 years and 80 years
Trial Updated:
07/14/2023
Locations: Case Western Reserve University, Cleveland, Ohio +3 locations
Conditions: Chronic Pain
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Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
NCT04603417
Recruiting
This study is designed to find behavioral and neurophysiological correlates of pain avoidance behavior among chronic pain patients, controlling for risk for opioid use disorder. Further, traits and risk factors that contribute to pain avoidance behavior will be investigated. The knowledge gained will broaden the current understanding of mechanisms involved in pain avoidance behavior in chronic pain patients, and help devise novel interventions.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/30/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Chronic Pain, Opioid Use
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Stepped Care for Patients to Optimize Whole Recovery
NCT05155163
Recruiting
This is a prospective, randomized clinical trial of 316 patients with opioid use disorder (OUD) and chronic pain (CP) to test the effectiveness of treatment as usual compared with Stepped Care for Patients to Optimize Whole Recovery (SC-POWR) to reduce illicit opioid use and pain interference (Aim 1) and decrease alcohol use, anxiety, depression, and stress, and improve sleep (Aim 2). Eligible participants will begin medications for opioid use disorder (MOUD) and will be randomized to receive SC... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: APT Foundation, New Haven, Connecticut +1 locations
Conditions: Opioid Use Disorder, Chronic Pain
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Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids
NCT04928157
Recruiting
Patients with chronic pain who use opioids appear to be at increased risk for breathing issues during sleep, termed sleep disordered breathing (SDB). Treatment of SDB often consists of use of a device during sleep that provides continuous positive airway pressure (CPAP) via a mask interface. The goal of this study is to determine whether patients with chronic pain who use opioids and have SDB might benefit from the use of CPAP in terms of sleep quality, pain, quality of life, and other measures.... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: University of California San Diego, San Diego, California
Conditions: Sleep Disorder; Breathing-Related, Pain, Sleep Apnea, Obstructive Sleep Apnea, Sleep, Sleep Disorder, Chronic Pain, Opioid Use
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Neuroimaging of Opioid Phase (OPAL)
NCT05905419
Recruiting
The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Chronic Pain, Opioid Use
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Effect of Music on Pain and Anxiety in Chronic Pain Patients Undergoing Lumbar Interventional Procedures.
NCT04924244
Recruiting
The purpose of this study is to evaluate, subjectively and objectively, whether playing music during procedures for treatment of chronic lower back pain has an effect on patients' anxiety and pain. The investigators hypothesize that playing music will result in reduced patient reported anxiety and pain scores and less variation from baseline of vital signs versus patients in the control group without music therapy. This is a pilot study.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Milton S. Hershey Medical Center, Hershey, Pennsylvania
Conditions: Chronic Pain, Anxiety
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Insula Neuromodulation for Chronic Neuropathic Pain
NCT05404581
Recruiting
This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/10/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Neuropathic Pain, Chronic Pain
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Patient Retrospective Outcomes (PRO)
NCT01550575
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Lakeside Spine & Pain, Lake Havasu City, Arizona +121 locations
Conditions: Chronic Pain
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Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment
NCT05875207
Recruiting
This study will use multiple methods to assess the feasibility of conducting a fully powered multisite clinical trial to test the effectiveness of integrating mindfulness-based interventions into physical therapy for patients with chronic musculoskeletal pain and long-term opioid treatment. First, researchers will develop a manual for training physical therapists to provide mindfulness-based interventions to patients with chronic musculoskeletal pain and long-term opioid treatment. Next, the re... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/09/2024
Locations: University of Florida, Gainesville, Florida +1 locations
Conditions: Chronic Pain, Pain, Musculoskeletal, Opioid Use, Physical Therapy
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Noninvasive Modulation of Chronic Neuropathic Pain
NCT06249724
Recruiting
This study will apply low-intensity transcranial focused ultrasound to dorsal root ganglia in patients with chronic neuropathic pain. The target will be validated using magnetic resonance imaging. The stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolerated stimulation protocol will be selected for subsequent testing in a blinded randomized sham-controlled cross-over trial. The level of pain will be evaluated... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/08/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Neuropathic Pain, Chronic Pain
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Pain Reduction Using NEurostimulation Study
NCT05311956
Recruiting
This is a 4-year project to see if a small battery-powered, device attached to a headband, that sits on the skin surface and delivers what is a hardly noticeable level of electrical stimulation can reduce pain in patients who receive hemodialysis on an ongoing basis.
Gender:
All
Ages:
21 years and above
Trial Updated:
05/07/2024
Locations: The Rogosin Institute, New York, New York +1 locations
Conditions: End Stage Kidney Disease, Chronic Pain
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