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Chronic Pain Clinical Trials
A listing of 146 Chronic Pain clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 146
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There are currently 146 active clinical trials seeking participants for Chronic Pain research studies. The states with the highest number of trials for Chronic Pain participants are California, Florida, Texas and New York.
Featured Trial
Healthy Participants Needed (Colonoscopy + Cancer Screening)
Recruiting
Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.
Conditions:
Healthy
Healthy Volunteers
Healthy Subjects
Healthy Volunteer
Healthy Participants
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $50 off your first program with code policy-lab-50.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $50 off your first program with code policy-lab-50.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Featured Trial
Get Your Illinois Medicinal Marijuana Card (10% Off)
Recruiting
Elevate Holistics connects patients with licensed physicians who guide them through their state’s eligibility process for qualifying conditions such as chronic pain, anxiety disorders, or sleep challenges. Compassionate, compliant care every step of the way.
Use code PACSHORE10 for 10% off your consultation fee.
For adults 21+ or qualifying patients under state law. Availability varies by state.
Use code PACSHORE10 for 10% off your consultation fee.
For adults 21+ or qualifying patients under state law. Availability varies by state.
Conditions:
Anxiety
Depression
Major Depressive Disorder
Pain
Chronic Pain
Featured Trial
Get Your Iowa Medicinal Marijuana Card (10% Off)
Recruiting
Elevate Holistics connects patients with licensed physicians who guide them through their state’s eligibility process for qualifying conditions such as chronic pain, anxiety disorders, or sleep challenges. Compassionate, compliant care every step of the way.
Use code PACSHORE10 for 10% off your consultation fee.
For adults 21+ or qualifying patients under state law. Availability varies by state.
Use code PACSHORE10 for 10% off your consultation fee.
For adults 21+ or qualifying patients under state law. Availability varies by state.
Conditions:
Anxiety
Depression
Major Depressive Disorder
Pain
Chronic Pain
Impact of 4PCP on Practitioner and Patient Outcomes
Recruiting
Reducing opioid prescribing and improving outcomes in patients with chronic pain would benefit our nation. Neither addiction nor chronic pain spares any race, gender, or particular socio-economic status. This study is investigating a potentially inexpensive way of providing a previously costly service (the intensive chronic pain rehabilitation program), which is why insurers stopped covering it. Although it is unusual for an application from an academic institution to include a startup company (... Read More
Gender:
ALL
Ages:
Between 14 years and 80 years
Trial Updated:
07/11/2025
Locations: Case Western Reserve University, Cleveland, Ohio +3 locations
Conditions: Chronic Pain
Retrospective-Prospective PNS Study
Recruiting
This is a retrospective-prospective study in which 40 patients have received a permanent Freedom PNS System. Subjects presented with chronic, intractable pain of peripheral nerve origin refractory to standard medical and/or surgical treatment.
A retrospective chart review will be conducted to assess baseline and follow-up parameters in patients who have received a permanent implant with the Freedom PNS system for at least 12 months. Missing data might be collected after informed consent.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: The Metrohealth System, Cleveland, Ohio
Conditions: Chronic Pain
Overlapping Pain Trajectory Study
Recruiting
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are:
1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls.
2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
08/20/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain
Recruiting
The purpose of this study is to evaluate the clinical utility of neurophysiological measurements of ECAP-controlled closed-loop SCS (i.e., neural panel metrics) to guide treatment of chronic pain of the trunk and/or limbs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Lakeside Spine and Pain, Lake Havasu City, Arizona +24 locations
Conditions: Chronic Pain
Brief Intervention for Chronic Pain and History of Stressful Experiences
Recruiting
The goal of this study is to understand whether a brief, three session program can be helpful in reducing symptoms related to both chronic pain and stressful experiences/trauma.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
08/18/2025
Locations: Brigham and Women's Hospital, Chestnut Hill, Massachusetts
Conditions: Chronic Pain, Trauma, Adverse Childhood Experiences
TMS-EEG Biomarkers for Chronic Pain
Recruiting
In this study the investigators aim to assess the correlates of neurophysiological measures (measurement of brain magnetically evoked response) using DELPHI system. The DELPHI system device is a computerized, electromechanical medical device that produces and delivers non-invasive Transcranial Magnetic Stimulation (TMS) fields to induce electrical currents directed at regions of the cerebral cortex and records the resultant Electroencephalogram (EEG) brain electrophysiological response. DELPHI a... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/15/2025
Locations: UCSF, San Francisco, California
Conditions: Chronic Pain
Effect of Music on Pain and Anxiety in Chronic Pain Patients Undergoing Lumbar Interventional Procedures.
Recruiting
The purpose of this study is to evaluate, subjectively and objectively, whether playing music during procedures for treatment of chronic lower back pain has an effect on patients' anxiety and pain. The investigators hypothesize that playing music will result in reduced patient reported anxiety and pain scores and less variation from baseline of vital signs versus patients in the control group without music therapy. This is a pilot study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Milton S. Hershey Medical Center, Hershey, Pennsylvania
Conditions: Chronic Pain, Anxiety
Under-Resourced Adults With Chronic Pain eHealth Study
Recruiting
The purpose of this study is to examine the feasibility of the dissemination of a cognitive-behavioral eHealth application (app) for pain self-management with Black and LGBTQ+ adults with high-impact chronic pain lasting at least 3 months and disrupting daily functioning (Implementation aim).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Chronic Pain
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2025
Locations: Lakeside Spine & Pain, Lake Havasu City, Arizona +141 locations
Conditions: Chronic Pain
A DirEct to PatieNt Study in Chronic Pain
Recruiting
To compile real-world, direct from patient clinical outcomes and objective metrics in patients who have received or plan to receive a commercially approved interventional medical device therapy/procedure for chronic pain in routine clinical practice.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
08/11/2025
Locations: Boston Scientific Neuromodulation, Valencia, California
Conditions: Chronic Pain
A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy
Recruiting
This trial seeks to establish whether or not touch sensation can be restored to the breast via neural stimulation. Data will also be obtained to inform future feasibility (including safety), efficacy, and acceptability trials.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/07/2025
Locations: University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois
Conditions: Mastectomy, Breast, Chronic Pain
Managing Chronic Tendon Pain by Metformin
Recruiting
The purpose of the current exploratory clinical trial is to determine the effect of oral ingestion of metformin (OIM) in non-diabetic patients with chronic Achilles tendon pain. The trial has two aims; 1) to assess the effects of OIM treatment on tendon pain, and 2) to determine the effects of OIM capsules on tendon healing and repair. Twenty participants will be treated with metformin capsules for 16 weeks combined with a home exercise program. A comparison group of 20 participants will be trea... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
08/06/2025
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Tendinopathy, Chronic Pain, Achilles Tendinopathy
1 - 12 of 146