There are currently 96 active clinical trials seeking participants for Head and Neck Cancer research studies. The states with the highest number of trials for Head and Neck Cancer participants are California, Ohio, Pennsylvania and New York.
COPD Care Pathway Among Patients With Cancer
NCT05984680
Recruiting
This study gathers information for the development of a COPD care pathway for patients with cancer that reduces the treatment burden of patients, implements critical components of COPD care, and overcomes common barriers to COPD care in the community oncology clinic.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Conditions: Chronic Obstructive Pulmonary Disease, Lung Cancer, Head and Neck Cancer
Register for Updates
Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
NCT02507141
Recruiting
The purpose of this study is to get images (pictures) of oral lesions, which occur inside the mouth, before the patient's surgery using a special camera. These pictures will be used in our research to evaluate a new technology that uses a laser and takes pictures of the microscopic structure of tissue. The technology is called "reflectance confocal microscopy." We would like to compare what the camera sees to biopsies (pathology) of the same area. We will evaluate the pictures obtained from the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/11/2025
Locations: Memorial Sloan Kettering Basking Ridge (consent only), Basking Ridge, New Jersey +4 locations
Conditions: Head and Neck Cancer, Squamous Cell Carcinoma (SCC) of the Oral Cavity
Register for Updates
Hypofractionated Preoperative Radiation for Head and Neck Cancers (HyPR-HN)
NCT05538533
Recruiting
This is a phase 1 study to determine the safety of a condensed preoperative radiation regimen (10, 7, or 5 fractions) for the management of head and neck squamous cell carcinoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Head and Neck Cancer
Register for Updates
New MRI Biomarkers in Head and Neck Cancers
NCT03483337
Recruiting
Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt. This makes specific organs, blood vessels, or tumors easier to see. Diffusion MRI lets us measure the motion of water in the tumor. The purpose of this study is to see if new MRI methods can give us more information about the tumor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Head and Neck Cancer, Thyroid Cancer
Register for Updates
Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma
NCT03875716
Recruiting
This research study is studying lowering the standard dose of radiation and chemotherapy after surgery, to minimize the side effects and improve the quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Head and Neck Cancer
Register for Updates
The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care
NCT04541381
Recruiting
Doctors leading this study hope to find out if giving study participants' genetic information to cancer care providers will help personalize chemotherapy dosing decisions and decrease common chemotherapy side effects. Doctors leading the study will collect genetic information from study participants using pharmacogenomics/genotyping. Pharmacogenomics is the study of how the differences in our genes can affect our unique response to medications. This is a randomized study, which means that parti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/04/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Gastrointestinal Cancer, Breast Cancer, Head and Neck Cancer, Dihydropyrimidine Dehydrogenase Deficiency, UGT1A1 Gene Mutation
Register for Updates
Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies
NCT05226871
Recruiting
The purpose of this clinical trial is to provide study medicine(s) and learn about their safety. This study is seeking participants who: * Have benefited from ongoing study treatment as determined by the study doctor in a Pfizer-sponsored palbociclib Parent Study * Must agree to follow the reproductive criteria * Are willing and able to comply with all scheduled visits, treatment plans, and other study procedures * Can give signed informed consent documents Participants in this study will cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2025
Locations: UCSF Medical Center at Mission Bay, San Francisco, California +21 locations
Conditions: Breast Cancer, Head and Neck Cancer
Register for Updates
Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life
NCT06667427
Recruiting
The goal of this research study is to measure changes in patients' quality of life after surgeries that affect the facial nerve, including nerve transfer as treatment for facial paralysis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: Cancer, Head and Neck Cancer
Register for Updates
Microbiome in Head and Neck Squamous Cell Carcinoma
NCT05837221
Recruiting
This study aims to determine whether dysbiosis actively contributes to HNSCC and if so, the underlying molecular mechanisms.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/31/2025
Locations: University of Colorado Cancer Center, Aurora, Colorado
Conditions: Head and Neck Cancer, Lip Cancer, Oral Cancer, Pharynx Cancer
Register for Updates
Tissue Sample Collection from Patients with Head and Neck Cancer and from Healthy Participants
NCT00898638
Recruiting
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing tissue samples from patients with head and neck cancer and from healthy participants.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/26/2025
Locations: Vanderbilt-Ingram Cancer Center - Cool Springs, Nashville, Tennessee +3 locations
Conditions: Head and Neck Cancer
Register for Updates
Preoperative Immunotherapy in Patients with Squamous Cell Carcinoma of the Head and Neck
NCT03708224
Recruiting
To determine the effect of neoadjuvant atezolizumab alone or in combination with other immune modulating agents on T-cell infiltration in advanced SCCHN. To determine the impact of neo-adjuvant immunotherapy on surgical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: University of San Francisco, California, San Francisco, California
Conditions: Cancer, Carcinoma, Squamous Cell Carcinoma, Head and Neck Cancer
Register for Updates
Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy
NCT06477692
Recruiting
To determine the risk of solitary elective volume recurrence following involved nodal radiotherapy (INRT) versus elective nodal irradiation (ENI)
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
01/24/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Head and Neck Cancer
Register for Updates