There are currently 118 active clinical trials seeking participants for Head and Neck Cancer research studies. The states with the highest number of trials for Autism participants are California, Ohio, Pennsylvania and New York.
Microbiome in Head and Neck Squamous Cell Carcinoma
NCT05837221
Recruiting
This study aims to determine whether dysbiosis actively contributes to HNSCC and if so, the underlying molecular mechanisms.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
01/12/2024
Locations: University of Colorado Cancer Center, Aurora, Colorado
Conditions: Head and Neck Cancer, Lip Cancer, Oral Cancer, Pharynx Cancer
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Imaging With a PET Agent for Detection of Cancers of the Head and Neck
NCT03631017
Recruiting
The purpose of this study is to test the safety of a study drug called PARPi-FL. This drug has been tested in animals but not yet in people. The purpose of this study is to test if a PARPi-FL scan can be used to take pictures of head and neck cancer. The usual approach to imaging this cancer includes several different imaging scans, including x-rays, CT (computed tomography), MRI (magnetic resonance imaging), and PET (positron emission tomography). These tests take pictures of the cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Head and Neck Cancer
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Enhanced Care Coordination for Head and Neck Cancer Survivors
NCT04813172
Recruiting
The purpose of this study is to evaluate the effect of a multidimensional symptom management intervention on decreasing symptom burden and thus reducing hospital utilization in patients undergoing radiation with or without chemotherapy for head and neck cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Eye and Ear Institute, Pittsburgh, Pennsylvania
Conditions: Head and Neck Cancer
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Medical Cannabis During Chemoradiation for Head and Neck Cancer
NCT03431363
Recruiting
The primary purpose of the study is to observe the adherence and health seeking behavior of patients with Head and Neck cancer (HNC) certified to obtain medically certified cannabis as part of their supportive care regimen undergoing treatment with definitive or adjuvant concurrent chemoradiation (CRT).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/02/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Head and Neck Cancer
Register for Updates
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
NCT04354064
Recruiting
Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular residual disease (MRD) detection timepoint. Ultimately, the integration of ctDNA into the clinical workflow has the potential to enh... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/02/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Healthy Volunteer, Prostate Cancer, Head and Neck Cancer, Esophageal Cancer, Genitourinary Cancer, Sarcoma, Breast Cancer, Colon Cancer, Gastrointestinal Cancer, Solid Tumor Cancer, Lung Cancer, Skin Cancer, Melanoma
Register for Updates
Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)
NCT05259696
Recruiting
This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/22/2023
Locations: UC San Diego Moores Cancer Center, La Jolla, California +12 locations
Conditions: Oncology, Melanoma, Ovarian Cancer, NSCLC, Non Small Cell Lung Cancer, Colorectal Cancer, Pancreatic Cancer, Cancer, CRC, Colon Cancer, Breast Cancer, Gastric Cancer, EGJ, Esophagogastric Junction Cancer, Head and Neck Cancer, Urothelial Cancer, Bladder Cancer
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Study of EOS-448 With Standard of Care and/or Investigational Therapies in Participants With Advanced Solid Tumors
NCT05060432
Recruiting
This is a multicenter, open-label, phase I/II basket study, evaluating the safety, tolerability, RP2D, pharmacokinetics, pharmacodynamics and antitumor activity of EOS-448 (also known as GSK4428859A or belrestotug) combined with standard of care and/or with investigational therapies in participants with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: University of California San Diego, San Diego, California +40 locations
Conditions: Advanced Cancer, Lung Cancer, Head and Neck Cancer, Melanoma
Register for Updates
Study of Proton Versus Photon Beam Radiotherapy in the Treatment of Head and Neck Cancer
NCT02923570
Recruiting
Compared to IMRT, PBRT is thought to give less radiation exposure to the surrounding healthy tissues. It is possible that side effect rates with PBRT will be lower or the same compared to IMRT, but this has not been well studied to date. Although both of these radiation therapies have been used in the past to treat head and neck cancer, this research study will compare the effects of these two different radiation treatment modalities with each other to see whether PBRT is better, the same or wor... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Baptist Alliance MCI, Miami, Florida +8 locations
Conditions: Head and Neck Cancer
Register for Updates
Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
NCT00568490
Recruiting
The purpose of this study is to identify and confirm new blood and tissue markers for prognosis and tumor hypoxia. Tumor hypoxia, or the condition of low oxygen in the tumor, has been shown to increase the risk of tumor spread and enhance tumor resistance to the standard treatment of radiation and chemotherapy in head and neck and lung cancers. We have recently identified several proteins or markers in the blood and in tumors (including osteopontin, lysyl oxidase, macrophage inhibiting factor an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/19/2023
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Head and Neck Cancer, Lung Cancer, Lip Cancer, Lip Neoplasms, Head and Neck Cancers
Register for Updates
Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
NCT00898638
Recruiting
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing tissue samples from patients with head and neck cancer and from healthy participants.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/18/2023
Locations: Vanderbilt-Ingram Cancer Center - Cool Springs, Nashville, Tennessee +3 locations
Conditions: Head and Neck Cancer
Register for Updates
Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation
NCT05650710
Recruiting
Recently published data suggest that stimulation of the infrahyoid strap muscles increases pharyngeal patency in patients with obstructive sleep apnea, but the innervation of these muscles by the ansa cervicalis is variable. The investigators propose a study examining the anatomic variation of the ansa cervicalis and the effect of neurostimulation on muscle recruitment.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/18/2023
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Head and Neck Cancer, Obstructive Sleep Apnea
Register for Updates
Carotid Ultrasound to Identify Head and Neck Cancer Survivors With High Cardiovascular Risk After Radiation Therapy
NCT05490875
Recruiting
The purpose of this research study is to understand how radiation therapy may affect blood vessels in the neck called the carotid arteries. Investigators want to look at narrowing of the artery or thickening of the walls of the arteries.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/14/2023
Locations: Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Conditions: Head and Neck Cancer, Carotid Artery Stenosis, Cardiovascular Complication
Register for Updates