There are currently 108 active clinical trials seeking participants for Head and Neck Cancer research studies. The states with the highest number of trials for Head and Neck Cancer participants are California, Ohio, Pennsylvania and New York.
A Prospective Imaging Study of the Integrated TrueBeam-HyperSight CBCT System
Recruiting
Cone beam computed tomography (CBCT) images are routinely used in radiation treatment delivery workflows to align patients with the treatment beam. Conventional CBCT image quality is sufficient for this task but not good enough for other radiotherapy-related tasks, such as contouring anatomical structures and calculating radiation dose distributions. HyperSight is a new CBCT imaging system manufactured by Varian Medical Systems. The purpose of this study is to evaluate the integration of the Hyp... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/27/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Head and Neck Cancer, Thoracic Cancer, Abdominal Cancer, Pelvic Cancer
"QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer
Recruiting
The purpose of this study is to test the safety of palliative "QUAD SHOT" radiotherapy combined with pembrolizumab and evaluate the effects of the combination treatment patients with recurrent cancer of head and neck.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Stephenson Cancer Center, Oklahoma City, Oklahoma
Conditions: Head and Neck Cancer
New MRI Biomarkers in Head and Neck Cancers
Recruiting
Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt. This makes specific organs, blood vessels, or tumors easier to see. Diffusion MRI lets us measure the motion of water in the tumor. The purpose of this study is to see if new MRI methods can give us more information about the tumor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Head and Neck Cancer, Thyroid Cancer
Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma
Recruiting
This research study is studying lowering the standard dose of radiation and chemotherapy after surgery, to minimize the side effects and improve the quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Head and Neck Cancer
A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Recruiting
Phase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: UCLA Hematology/Oncology, Los Angeles, California +10 locations
Conditions: Solid Tumor, Adult, Advanced Solid Tumor, Head and Neck Cancer, Breast Cancer, Colon Cancer, Pancreatic Cancer, Gastric Cancer, Esophageal Cancer, Prostate Cancer, Uterine Cancer, Cervix Cancer, Ovarian Cancer, Kidney Cancer, Bladder Cancer, Thyroid Cancer, Melanoma, Sarcoma, Advanced Cancer, Metastatic Cancer, Refractory Cancer, Non Small Cell Lung Cancer, Merkel Cell Carcinoma
Hypofractionated Preoperative Radiation for Head and Neck Cancers (HyPR-HN)
Recruiting
This is a phase 1 study to determine the safety of a condensed preoperative radiation regimen (10, 7, or 5 fractions) for the management of head and neck squamous cell carcinoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/07/2025
Locations: Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Head and Neck Cancer
Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer
Recruiting
The purpose of this study is to examine the uses of a mobile health-based assessment and symptom monitoring platform.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2025
Locations: Stephenson Cancer Center, Oklahoma City, Oklahoma
Conditions: Head and Neck Cancer, Gynecologic Cancer, Cervical Cancer, Endometrial Cancer
WeCanManage. An mHealth Self-management Tool
Recruiting
Examine the Feasibility, Acceptability, User Satisfaction, and Response Patterns and Preliminary Efficacy on Targeted Patient Reported Outcomes. Using a pre-post, single arm feasibility design with cancer survivors with disabilities
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2025
Locations: University of Illinois, Chicago, Illinois
Conditions: Breast Cancer, Head and Neck Cancer, Sarcoma
Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer
Recruiting
Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol. It might reduce the risk of cisplatin-induced hearing loss. Objective: To find out if atorvastatin reduces hearing loss in people treated with cisplatin and radiation. Eligibility: People ages 18 and older with squamous cell carcinoma of the head and neck who will undergo treatment with cisplatin-based chemotherapy and ra... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
02/06/2025
Locations: Winship Cancer Institute at Emory University, Atlanta, Georgia +3 locations
Conditions: Hearing Loss, Head and Neck Cancer
The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care
Recruiting
Doctors leading this study hope to find out if giving study participants' genetic information to cancer care providers will help personalize chemotherapy dosing decisions and decrease common chemotherapy side effects. Doctors leading the study will collect genetic information from study participants using pharmacogenomics/genotyping. Pharmacogenomics is the study of how the differences in our genes can affect our unique response to medications. This is a randomized study, which means that parti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/04/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Gastrointestinal Cancer, Breast Cancer, Head and Neck Cancer, Dihydropyrimidine Dehydrogenase Deficiency, UGT1A1 Gene Mutation
Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery
Recruiting
The goal of this clinical trial is to determine whether accelerated radiotherapy (involving 6 treatments per week) is better than standard radiotherapy (involving 5 treatments per week) at treating cancer of the head and neck when initiated more than 6 weeks after surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: Levine Cancer Institute, Charlotte, North Carolina +2 locations
Conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma HNSCC
Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies
Recruiting
The purpose of this clinical trial is to provide study medicine(s) and learn about their safety. This study is seeking participants who: * Have benefited from ongoing study treatment as determined by the study doctor in a Pfizer-sponsored palbociclib Parent Study * Must agree to follow the reproductive criteria * Are willing and able to comply with all scheduled visits, treatment plans, and other study procedures * Can give signed informed consent documents Participants in this study will cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2025
Locations: UCSF Medical Center at Mission Bay, San Francisco, California +21 locations
Conditions: Breast Cancer, Head and Neck Cancer