Rural New England Health Study (Phase 2)
NCT05466331
Recruiting
This study will integrate mobile hepatitis C virus (HCV) testing and treatment with expanded syringe access in order to improve uptake of HCV testing and treatment, and reduce syringe sharing behavior in rural northern New England. The intervention aims to reach rural opioid injectors with HCV and to fill service gaps identified around access to syringe services and HCV testing and treatment, while limiting the burden on local partners. If effective, this mobile model of HCV telehealth integrate... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Mobile Study Van, Keene, New Hampshire +2 locations
Conditions: Hepatitis C, Opioid Use Disorder, IV Drug Usage
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HCV Test and Treat Utilizing Simplified HCV Patient Education
NCT05582681
Recruiting
The study hypothesis is that the test and treat model utilizing video-based patient education will have higher rates of hepatitis C virus (HCV) treatment initiation and treatment completion.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/08/2023
Locations: Phoenix House, Long Island City, New York +2 locations
Conditions: Hepatitis C
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Evaluation of Patients With Liver Disease
NCT00001971
Recruiting
The proposed study aims to evaluate, investigate, and follow-up patients suffering from acute and chronic liver disease. The study will focus on understanding diseases affecting the liver. Patients participating in the study will first undergo a routine check-up as an outpatient. They will be asked to provide blood and urine samples for laboratory testing and will undergo an ultrasound of the liver. Ultrasound examinations use sound waves to determine the size and texture of the liver. After th... Read More
Gender:
All
Ages:
2 years and above
Trial Updated:
11/04/2023
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Liver Disease, Hepatitis D, Hepatitis C, Hepatitis B
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Advanced Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants
NCT04701437
Recruiting
The overarching goal of this study is to develop a peer-based care coordination intervention for individuals with HCV who were recently released from correctional settings to promote linkage to and retention in HCV care. The investigators will assess the existing barriers and facilitators of HCV treatment initiation, HCV treatment completion, and sustained virologic response among individuals recently released from a U.S. jail or prisons in a randomized control trial. This study will assess the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Prisma Health-Upstate, Greenville, South Carolina
Conditions: Hepatitis C
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Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
NCT05181826
Recruiting
To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for the detection of various types of cancer, ii) identifying benign conditions that may induce false positive or false negative results, and iii) defining the effects of potential interfering substances, such as chemotherapy drugs.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/10/2023
Locations: Torrance Memorial Physician Network - Cancer Care, Redondo Beach, California +6 locations
Conditions: Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B, Hepatitis C, Diabetes, COPD
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Project I Test: Implementing HIV Testing in Opioid Treatment Programs
NCT03135886
Recruiting
This study will test two active evidence-based "practice coaching" (PC) interventions to improve opioid treatment programs' (OTPs') provision and sustained implementation of on-site 1) HIV testing and linkage to care and 2) HIV/Hepatitis C virus (HCV) testing and linkage to care among patients seeking/receiving substance use disorder treatment. Aims are: Aim 1: To evaluate the effectiveness of the PC interventions on improving patient uptake of HIV testing in OTPs including the incremental imp... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/16/2023
Locations: Columbia University Medical Center, New York, New York
Conditions: HIV/AIDS, Hepatitis C, Substance Use Disorders, Opioid-use Disorder
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Blood Collection Biorepository for Liver Disease Research
NCT03025074
Recruiting
The purpose of establishing a biorepository is to provide high quality specimens (serum, plasma, buffy coat and liver tissue) for future researchers who are studying the effects that fatty liver and viral diseases have on the liver.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/02/2023
Locations: University at Buffalo, Buffalo General Medical Center, Buffalo, New York
Conditions: Non-Alcoholic Steatohepatitis(NASH), Hepatitis C, Hepatitis B, Fibrosis, Cirrhosis, Fatty Liver, Obesity, Childhood, Bariatric Surgery Candidate
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Hepatitis C Treatment in Probation and Parole Office
NCT05413785
Recruiting
This prospective cohort study compares aims to determine the efficacy and effectiveness of telemedicine-supported on-site linkage to care and treatment in a community probation and parole office (P&P office) setting and compare the results with a historic control with referral to care. Research participants will be followed in the P&P office when they report to their officer during regularly scheduled appointments. Participants will receive treatment without having to travel to a specialist's of... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/18/2023
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Hepatitis C, HCV
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Proteogenomic Monitoring and Assessment of Liver Transplant Recipients
NCT01644903
Recruiting
This study is being done to test blood, urine and tissue samples to see if this can help decide if CKD (Chronic Kidney Disease), AR (Acute Rejection) and HCV (Hepatitis C Virus) can be identified in its early stages. CKD damage to the kidneys, AR and HCV all lower the body's ability to function properly. Early detection of these conditions could assist with successful treatment and possibly lead to less repeat organ transplants.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2023
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Liver Transplant, Hepatitis C, Chronic Kidney Disease, Acute Rejection
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Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum
NCT04162938
Recruiting
The investigators will conduct a randomized controlled clinical trial study in an urban emergency department in Baltimore to determine the impact of an educational app which is based on Leventhal's Common-Sense Model of Illness Representations framework, on HCV-infected ED patient's hepatitis C virus (HCV) health belief and knowledge as well as the downstream outcomes of the HCV Continuum of Care (linkage to care rate, initiation of HCV antiviral treatment, and sustained virologic response). Fir... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
03/28/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Hepatitis C
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The HOPE Study: Characterizing Patients With Hepatitis B and C
NCT02995252
Recruiting
This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C. Participants will be seen on an annual basis with optional additional visits for up to 10 years and provide samples for research and evaluation of disease progression. In addition, there is a longitudinal sub-study for treatment of hepatitis B that will involve 2 years of treatment with tenofovir alafenamide and blood collections w... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/10/2023
Locations: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland +1 locations
Conditions: Hepatitis B， Chronic, Hepatitis C
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The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing
NCT01280825
Recruiting
The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be made available to the patient's treating physician and the researchers will track whether or not this information is used in routine health care.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2023
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Patients Undergoing Routine Health Care, Heart Diseases, Inflammatory Bowel Diseases, Autoimmune Disease, Inflammatory Disease, Blood Coagulation Disorders, Hepatitis C, Non-Metastatic Neoplasm
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