There are currently 339 active clinical trials seeking participants for Obesity research studies. The states with the highest number of trials for Obesity participants are California, Texas, Florida and New York.
Early Tracking of Childhood Health Determinants (ETCHED) Study
NCT03481829
Recruiting
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term effects on the child s health. Children who become overweight or obese during childhood tend to remain so as adults. Researchers want to study many risk factors during and after pregnancy, and how these affect a child s development. They will also follow the mother s he... Read More
Gender:
ALL
Ages:
Between 1 day and 99 years
Trial Updated:
03/19/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Fatty Liver, Diabetes Mellitus
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Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
NCT04714892
Recruiting
Background: Changes to the sense of taste or smell can change eating behavior. This may contribute to obesity. Researchers want to see how taste and smell perceptions that affect food choices may differ between people with obesity and without obesity. Objective: To understand the role that senses of taste and smell play in food intake. Eligibility: Adults ages 18-65 with obesity and without obesity Design: Participants will be screened with a medical history and physical exam. They will h... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity
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Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
NCT06466161
Recruiting
The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia. An improvement in diagnostic accuracy of even 5mm Hg would be significant, as reflected by the US Association for the Advancement of Medical Instrumentation (AAMI), the British Hypertension Society, the European Society of Hypertension (ESH) Working Group on Blood Pressure (BP) Moni... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: Prentice Women's Hospital, Chicago, Illinois
Conditions: Hypertension in Pregnancy, Hypertension, Obesity
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A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo
NCT06131372
Recruiting
This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2D) and overweight or obesity. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors. The study will compare CagriSema to the 2 medicines semaglutide and cagrilintide, when they are taken alone. It will also compare CagriSema to a "dummy" medicine (also called placebo) without any active ingredient. Participant will either get CagriSema, se... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: John Muir Physicians Network, Concord, California +139 locations
Conditions: Chronic Kidney Disease, Type 2 Diabetes, Obesity
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A Single-center Study of Setmelanotide in Patients With Prader-Willi Syndrome
NCT06772597
Recruiting
This is a Phase 2, single-center, open-label study designed to assess the safety and efficacy of setmelanotide in patients with obesity due to Prader-Willi Syndrome (PWS) who are 6 to 65 years of age. Up to 20 patients are planned to be enrolled. Patients will take a daily subcutaneous dose of open-label setmelanotide for up to 26 weeks.
Gender:
ALL
Ages:
Between 6 years and 65 years
Trial Updated:
03/18/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Prader-Willi Syndrome, Obesity, Hyperphagia
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Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions
NCT06393725
Recruiting
The goal of this clinical trial is to learn if a group-based digital weight loss program that is delivered asynchronously (via an online platform) is as effective as one that is delivered synchronously (via weekly videoconference meetings). In the asynchronous condition, participants can engage with their group any time 24/7. In the synchronous condition, participants can engage with their group once a week at a videoconference meeting. The main questions it aims to answer are: Will participant... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2025
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Obesity
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Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise
NCT06602141
Recruiting
The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin sensitivity in men and women.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/17/2025
Locations: AdventHealth Translational Research Institute, Orlando, Florida +1 locations
Conditions: Obesity
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Collaborative Multi-level Obesity Intervention Engaging Underserved Communities Trial
NCT06835686
Recruiting
The goal of this clinical trial is to test the effectiveness of an evidence-based multi-level intervention for weight loss and the feasibility, fidelity, and sustainability of implementing the intervention in low-income and underserved people living with obesity in Louisiana. The main questions it aims to answer are: * Will an evidence-based multi-level obesity intervention (called LA-CEAL CONNECT) in adults living with obesity in low-income and underserved communities achieve weight loss at 6... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/17/2025
Locations: InclusivCare - Avondale Clinic, Avondale, Louisiana +17 locations
Conditions: Obesity
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Reducing Obesity Using Social Ties Program
NCT06335810
Recruiting
This trial aims to test the feasibility and acceptability of addressing interpersonal barriers to weight-related behavior change. Specifically, the study will test if, by including up to two friends, family members, or co-workers in a lifestyle intervention for weight loss, the person enrolled in the study loses more weight than someone whose friends, family members, or co-workers were not invited to participate.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Obesity
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Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
NCT00739362
Recruiting
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person eats and weight loss over 4 weeks. It will also compare weight changes in people who attend weight loss counseling sessions and those who do not over this period of time. Obese, non-diabetic people between 18 and 60 years of age who are in good health and who live in the... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
03/14/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Electric Stimulation Therapy, Obesity, Weight Loss, Eating
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Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
NCT06730113
Recruiting
Background: Type 2 diabetes is a disease that affects blood sugar levels. Complications can include heart and blood vessel (vascular) diseases. Rates of type 2 diabetes have tripled in children and young adults over the last 40 years. Vascular diseases are also increasing in young people. Objective: To learn more about factors, including type 2 diabetes, that may cause vascular disease in young people. Eligibility: People aged 12 to 25 years who (1) have type 2 diabetes; (2) are overweight... Read More
Gender:
ALL
Ages:
Between 12 years and 25 years
Trial Updated:
03/14/2025
Locations: Children's National Hospital (CNH), Washington, District of Columbia +1 locations
Conditions: Obesity, Type 2 Diabetes
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Experimental Approach to Test Predictions of Body Weight Regulation Models
NCT06309576
Recruiting
The regulation of human body weight and fatness is not fully understood. Although some models of regulation have been proposed (set point, dual-intervention point, others), no studies have been designed to test their predictions. In this pilot and feasibility study, the investigators will implement an experimental approach to test the predictions of models of body weight regulation in humans. Men and women with either low body weight or obesity will be exposed to a 2-day fasting followed by a 2-... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
03/14/2025
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Obesity, Underweight
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