There are currently 347 active clinical trials seeking participants for Obesity research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and New York.
A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight
NCT06309992
Recruiting
This study is open to adults who are at least 18 years old and have presumed or confirmed NASH together with overweight or obesity and a body mass index (BMI) of 30 kg/m² or more, or a BMI of 27 kg/m² and at least one weight-related health problem. People with a history of other chronic liver diseases cannot take part in this study. The purpose of this study is to find out whether a medicine called survodutide helps people living with obesity or overweight and a confirmed or presumed liver di... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Excel Medical Clinical Trials, Boca Raton, Florida +3 locations
Conditions: Obesity, Non-Alcoholic SteatoHepatitis (NASH)
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Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention
NCT01927783
Recruiting
Background: - Past studies suggest that the best way to improve heart health in the Black community is through community-based programs. Researchers will partner with DC community leaders. They will collect information about the health and health needs of people in mostly Black churches in DC. They will study things that affect heart health, like diabetes, blood pressure, cholesterol, and weight. They will also study how technology can keep track of activities and health. The information will s... Read More
Gender:
All
Ages:
Between 19 years and 85 years
Trial Updated:
04/27/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cardiovascular Disease, Obesity
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Children s Growth and Behavior Study
NCT02390765
Recruiting
Background: - Studies show that many factors affect children s eating behavior and health. These include sleep, mood, thinking skills, and genetics. Studying children over time may identify children at higher risk for eating-related health concerns. Objective: - To understand how genes and environment influence eating behavior and health over time. Eligibility: - Children ages 8 17 in good general health. Design: Screening visit 1: Medical history, physical exam, body measurements, and qu... Read More
Gender:
All
Ages:
8 years and above
Trial Updated:
04/27/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity, Eating Behaviors, Healthy Volunteers
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The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
NCT05545306
Recruiting
Background: Diet-induced thermogenesis (DIT) is the amount of energy one s body uses to eat food, absorb the nutrients from the food, and process those nutrients. Researchers would like to understand more about how changing the balances of protein, fat, carbohydrates, and total calories in the diet can affect DIT. Objective: To learn how different diets can change a person s DIT. Eligibility: Healthy people aged 18 to 60 years who have not intentionally lost weight in the past 6 months. De... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/27/2024
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Normal Physiology, Healthy Volunteers
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Physical and Behavioral Traits of Overweight and Obese Adults
NCT00428987
Recruiting
This study will describe the phenotype (physical and behavioral traits) of overweight and obese people. It will characterize the hormones, metabolism, food preferences, fitness and physical activity levels, sleep patterns and thought processes in people with and without weight problems. Genetic material will be collected for studies of the internal codes that influence body weight. People over 18 years of age from all weight categories (lean, overweight, obese) who are reasonably healthy may be... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
04/25/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity, Healthy Volunteers
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Diet Tracking Prescriptions for Weight Loss
NCT06311175
Recruiting
Lifestyle interventions are effective at producing modest weight loss. One of the strongest predictors of weight loss is food tracking, which involves logging all food and beverage consumed each day in an effort to stay within a daily calorie goal. Standard lifestyle interventions prescribe daily food tracking for the length of the program which can range from 3-24 months. This can be a taxing prescription that is not feasible to do long term for many people. The purpose of this pilot feasibilit... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/24/2024
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Obesity
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Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
NCT00739362
Recruiting
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person eats and weight loss over 4 weeks. It will also compare weight changes in people who attend weight loss counseling sessions and those who do not over this period of time. Obese, non-diabetic people between 18 and 60 years of age who are in good health and who live in the... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/24/2024
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Electric Stimulation Therapy, Obesity, Weight Loss, Eating
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Investigating the Impact of Obesity on Pubertal Development in Girls
NCT02583646
Recruiting
Background: Studies suggest that overweight girls may be developing breast tissue, and therefore starting puberty, earlier than normal weight girls. However, it is hard to distinguish breast tissue from fatty tissue. Researchers think that by using breast ultrasound, among other tests, they can do a better job of telling whether an overweight girl has breast tissue. This will help them understand if overweight girls are truly entering puberty before normal weight girls. Objective: To find out... Read More
Gender:
Female
Ages:
Between 8 years and 14 years
Trial Updated:
04/24/2024
Locations: NIEHS, Research Triangle Park, Research Triangle Park, North Carolina
Conditions: Obesity, Puberty, Normal Physiology
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Early Tracking of Childhood Health Determinants (ETCHED) Study
NCT03481829
Recruiting
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term effects on the child s health. Children who become overweight or obese during childhood tend to remain so as adults. Researchers want to study many risk factors during and after pregnancy, and how these affect a child s development. They will also follow the mother s he... Read More
Gender:
All
Ages:
Between 1 day and 99 years
Trial Updated:
04/24/2024
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Fatty Liver, Diabetes Mellitus
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A Role for FGF21 in Postprandial Nutrient Homeostasis After RYGB
NCT03091725
Recruiting
Bariatric surgery markedly improves glycemic control in persons with Type 2 Diabetes (T2D). Roux-en-Y gastric bypass (RYGB), a procedure that bypasses the upper gastrointestinal (UGI) tract, results in greater rates of diabetes resolution compared to methods that leave the UGI tract intact. Studies suggest that mechanisms beyond weight-loss account for the superiority of RYGB compared to other surgical methods. These weight-loss independent metabolic effects may involve increased postprandial pr... Read More
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
04/24/2024
Locations: Beth Henk, Saint Louis, Missouri
Conditions: Obesity
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A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity
NCT06037252
Recruiting
The main purpose of this study is to learn more about the safety and efficacy of investigational tirzepatide doses in participants with Type 2 diabetes and obesity that are already taking metformin. The study will last for about 89 weeks.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/23/2024
Locations: Medical Advancement Centers of Arizona, Tempe, Arizona +58 locations
Conditions: Type 2 Diabetes, Obesity
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Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)
NCT06098079
Recruiting
A randomized, double-blinded, placebo controlled study intended to capture cardiovascular outcomes during real-world use of naltrexone/bupropion (NB).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Accel Research Sites Network, Birmingham, Alabama +93 locations
Conditions: Obesity
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