There are currently 341 active clinical trials seeking participants for Obesity research studies. The states with the highest number of trials for Obesity participants are California, Texas, Florida and New York.
The Effects of Glucagon on Hepatic Metabolism
NCT05500586
Recruiting
Whether impaired postprandial glucagon suppression in prediabetes and T2DM is an attempt to overcome resistance to glucagon's actions on hepatic AA catabolism, a defect in α-cell function, or a combination of both are important, unanswered questions. NAFLD is associated with T2DM risk and impaired insulin action. Unfortunately, it is unclear if glucagon resistance is caused by obesity, hepatic steatosis or both. The experiments outlined will determine if glucagon's actions on hepatic amino acid... Read More
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
05/28/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Obesity, Type2diabetes, NAFLD
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A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight
NCT06326060
Recruiting
This study will look at how a new medicine called NNC0519-0130 helps people with excess body weight lose weight. The study will test up to 6 different doses of NNC0519-0130. Participants will take 1-2 injections once a week. The study medicine will be injected under skin with a thin needle in the stomach, thigh, or upper arm. The study will last for about 42 weeks.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/27/2024
Locations: Centricity Research-Arizona, Mesa, Arizona +51 locations
Conditions: Obesity
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A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
NCT06075667
Recruiting
The main purpose of this study is to evaluate the safety and efficacy of tirzepatide in adolescents that have obesity or overweight with at least one weight-related comorbidity. The study will last approximately 90 weeks and may include up to 25 visits.
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
05/27/2024
Locations: CenExel iResearch, LLC, Decatur, Georgia +38 locations
Conditions: Obesity, Overweight
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A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity
NCT06373146
Recruiting
The main purpose of this study is to determine if combining tirzepatide with the mibavademab will result in more weight loss in adult participants than tirzepatide alone. The study will last about 72 weeks and may include up to 19 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: Velocity Clinical Research, Gardena, Gardena, California +23 locations
Conditions: Obesity
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Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health
NCT02706262
Recruiting
The purpose of this research study is to 1) understand how some, but not all people with obesity develop obesity related conditions such as type 2 diabetes and cardiovascular disease, and 2) compare the effects of 3 popular weight loss diets (Mediterranean, low-carbohydrate, or a very-low-fat plant-based diet) in people with obesity.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/22/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Obesity, Insulin Resistance
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Anti-obesity Pharmacotherapy and Inflammation
NCT05756764
Recruiting
This study evaluates the relationship between weight loss, circulating inflammatory markers and lipids from 24 patients before and after 6 months of pharmacotherapy as a standard of care for anti-obesity treatment
Gender:
All
Ages:
Between 35 years and 60 years
Trial Updated:
05/22/2024
Locations: LSU Clinical & Translational Research Center (CTRC - - LSUHSC-NO, New Orleans, Louisiana +1 locations
Conditions: Obesity
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Ultrasonic Treatment of Food Addiction
NCT06249711
Recruiting
This study will evaluate a new form of non-invasive deep brain therapy for food addiction. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolerated stimulation protocol will be selected for subsequent testing in a blinded randomized sham-controlled trial. The trial will evaluate brain target engagement using magnetic resonance imaging, Food Cravings Questionnaire-... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/21/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Overweight, Obesity
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Precision Nutrition and Metabolic Function
NCT04131166
Recruiting
The purposes of this study are: 1) to determine the mechanisms responsible for the development of cardiometabolic complications in some, but not all people with obesity; 2) determine the best dietary approach for cardiometabolic health; and 3) understand why some people have a stable metabolic phenotype over time whereas cardiometabolic health improves or worsens in others.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/21/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Obesity, Insulin Resistance
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A 16-Week Study to Evaluate the Efficacy, Safety, and Tolerability of GLY-200 in Participants With Obesity
NCT06259981
Recruiting
This study will evaluate the efficacy, safety, and tolerability of GLY-200 in participants with obesity.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/20/2024
Locations: Tampa Bay Medical Research, Inc., Clearwater, Florida +4 locations
Conditions: Obesity
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With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
NCT05721976
Recruiting
The purpose of this study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile-phone-based) program to improve lifestyle behaviors (physical activity, dietary intake) among Hispanic female cancer survivors and adult daughters.
Gender:
Female
Ages:
21 years and above
Trial Updated:
05/17/2024
Locations: University of Miami, Miami, Florida
Conditions: Cancer, Breast, Cancer, Uterus, Cancer, Ovary, Obesity, Activity, Motor, Diet, Healthy
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Ablation Registry (Combined Gastric Mucosal Ablation With Endoscopic Sleeve Gastroplasty for Weight Loss)
NCT06420700
Recruiting
The purpose of this study is to construct a multi-site, prospective registry to evaluate the clinical outcomes of patients who have undergone combined gastric mucosal ablation with endoscopic sleeve gastroplasty at True You Weight Loss.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/17/2024
Locations: True You Weight Loss, Atlanta, Georgia +1 locations
Conditions: Obesity
Register for Updates
Childcare Healthy Beverage Access, Food and Beverage Intake, and Obesity
NCT05112185
Recruiting
Interventions that promote water consumption in place of sugar-sweetened beverages have shown promise for preventing childhood obesity in schoolchildren. Yet to date, no studies have examined whether applying this approach in childcare centers could help to prevent childhood obesity at an even earlier stage of development. This cluster-randomized controlled trial will fill gaps by examining how a multilevel childcare-based healthy beverage intervention affects young children's consumption of bev... Read More
Gender:
All
Ages:
Between 2 years and 105 years
Trial Updated:
05/17/2024
Locations: Stanford, Stanford, California
Conditions: Obesity
Register for Updates