Delaware is currently home to 278 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Newark, Wilmington, Lewes and Rehoboth Beach. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Pediatric Anesthesia Quality Improvement Project
NCT00674388
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Nemours/Alfred I duPont Hospital for Children, Wilmington, Delaware
Conditions: Surgery, Anesthesia, Children
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Development and Validation of a Novel Eye-Tracking Software-based Platform to Extract Oculometric Measures
NCT05476523
Recruiting
This is an observational prospective study in a cohort of healthy subjects who are enrolled using convenience and snowballing sampling. The aims of the study is to demonstrate the efficacy of using NeuraLight system to capture oculometric data from healthy participants and to validate the data capture of NeuraLight oculometric measurements as compared with a validated eye-tracker system in subjects who meet the inclusion criteria and who provide a signed Informed Consent.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/07/2023
Locations: NeuraLight, Wilmington, Delaware
Conditions: Eye Movement
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EASE: The Materna Prep Pivotal Study
NCT03973281
Recruiting
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 12 months from the time of the use of the device d... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Christiana Care - Center for Women's & Children's Health, Newark, Delaware
Conditions: Vaginal Delivery, Pelvic Organ Prolapse
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Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling
NCT06008743
Recruiting
Stroke is the third leading cause of death and the primary cause of long-term disability in the United States, affecting approximately 795,000 people each year. Hemiparesis, or unilateral weakness, is common after stroke and responsible for changes in muscle activation and movement patterns as well as declines in walking speed. It has been shown that increased walking speed directly corresponds to a higher quality of life in older adults and therefore, is often the goal of motor rehabilitation a... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/20/2023
Locations: University of Delaware, Newark, Delaware
Conditions: Stroke
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Recasting or Book Reading by Parents or Clinicians
NCT05099328
Recruiting
Developmental Language Disorder (DLD) affects approximately seven percent of the population and is characterized by grammatical deficits that cascade into lifelong academic challenges and under-employment. Current treatments for DLD produce good outcomes under ideal, high intensity conditions or when parents have been trained to deliver therapy using intense coaching methods; however, current publicly funded service delivery systems and private-pay reimbursement models do not support treatment b... Read More
Gender:
ALL
Ages:
Between 4 years and 9 years
Trial Updated:
08/16/2023
Locations: University of Delaware, Newark, Delaware
Conditions: Developmental Language Disorder and Language Impairment
Register for Updates
The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
NCT03631225
Recruiting
The goal of treating patients diagnosed with rheumatoid arthritis (RA) is to achieve remission or low disease activity and thereby prevent joint damage, loss of physical function, and disability. Optimal management requires regular assessment of disease activity, with treatment changes made as needed for optimal efficacy. Vectra is a blood serum test that looks at 12 biomarkers and produces a score on a scale of 1 to 100. The Vectra score has been shown to be the strongest predictor of risk for... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: Delaware Arthritis, Lewes, Delaware
Conditions: Rheumatoid Arthritis (RA)
Register for Updates
Vaginal Care System for Menopausal Women With Urinary Tract Infections
NCT05573334
Recruiting
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause. As estrogen falls, the vaginal microbiome shifts from a healthy one to a less healthy one. Because the vagina is close to the urethra, this vaginal microbiome shift contributes to a loss of protection against urinary tract infections (UTIs). The investigators are asking whether improving the vaginal microbiome using an over-the-counter vaginal... Read More
Gender:
FEMALE
Ages:
89 years and below
Trial Updated:
07/17/2023
Locations: Center for Urogynecology & Pelvic Reconstructive Surgery, Newark, Delaware
Conditions: Urinary Tract Infections, Vaginal Flora Imbalance
Register for Updates
Simple Bone Cysts in Kids
NCT02193841
Recruiting
Simple bone cysts (SBCs) are cysts filled with fluid that occur most frequently in the long bones (arms or legs) of children. There are many ways to treat SBCs but it is unclear if one is better than another. The purpose of this research trial is to compare the effectiveness of two common treatments that are used by surgeons today.
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
07/10/2023
Locations: Nemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware
Conditions: Bone Cyst
Register for Updates
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
NCT05161429
Recruiting
An observational study of electronic patient data to compare diabetes medications and to determine which ones offer the best balance of risks and benefits.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
06/16/2023
Locations: HealthCore, Inc., Wilmington, Delaware
Conditions: Diabetes Mellitus, Type 2
Register for Updates
The Potassium Supplementation Study
NCT05887622
Recruiting
This study will test whether potassium supplementation can reduce the deleterious effect of a high sodium diet on blood vessel function, blood pressure reactivity and autonomic nervous system function in apparently healthy adults.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/30/2023
Locations: Tower at STAR, Newark, Delaware
Conditions: Cardiovascular Health, Cardiovascular Risk Factor
Register for Updates
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
NCT04798378
Recruiting
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one arm sufficient to perform daily activities. This study could lead to the development of a product that could allow people with arm weakness or arm paralysis to use the NuroSleeve and similar devices to improve arm health and independent function.
Gender:
ALL
Ages:
4 years and above
Trial Updated:
04/11/2023
Locations: Nemours Children's Hospital, Wilmington, Delaware
Conditions: Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Register for Updates
Intervening With Opioid-Dependent MothersMothers and Infants
NCT04454645
Recruiting
This study will assess the efficacy of the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention, adapted for use with peripartum mothers receiving medication-assisted treatment for opioid use disorder. The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and more adaptive physiological regulation than parents who receive a control intervention. The investigators expect that... Read More
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
03/09/2023
Locations: University of Delaware, Newark, Delaware
Conditions: Opioid Dependence, Parenting, Infant Development
Register for Updates