There are currently 131 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Pennsylvania.
CONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI)
NCT06134180
Recruiting
The intervention being tested, CONFIDENCE-AI is a refined version of the original CONFIDENCE intervention made to reduce psychological financial strain and improve management of out-of-pocket care costs while increasing caregiver resourcefulness skills. Participants will be asked to participate in a 4-week intervention that includes participation in four, synchronous group-based Zoom sessions as well as between-session activities to apply learning. Participants will also receive tailored text me... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Alzheimer Disease, Dementia, Caregiver Burden, Financial Stress
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Learning Skills Together Family Caregiver Complex Intervention
NCT05846984
Recruiting
Learning Skills Together (LST) is a 6-week psychoeducational intervention focused on complex care (nursing) tasks completed by family caregivers to persons living with Alzheimer's Disease and related dementias. This study aims to test the efficacy of LST at reducing caregiver depression and negative appraisal of behavioral symptoms of dementia by building caregiver self-efficacy. To do this, eligible participants will be randomized into an intervention group (LST) or a control group condition fo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Dementia, Alzheimer Disease, Caregiver Burden, Self Efficacy
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LifeBio Memory Digital Reminiscence Platform
NCT04769466
Recruiting
Non-pharmacological interventions and person-centered care strategies are important elements of care for people with Alzheimer's disease and related dementias. Life story work, which uses written and oral life histories to elicit conversation and memories, is an effective intervention for individuals with dementia; however, because of the time-consuming nature of generating useful life story materials, has not been widely implemented in nursing homes and other care environments. LifeBio Inc. wil... Read More
Gender:
All
Ages:
Between 18 years and 112 years
Trial Updated:
07/27/2023
Locations: Benjamin Rose Institute on Aging, Cleveland, Ohio
Conditions: Dementia, Cognitive Impairment
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Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
NCT05643144
Recruiting
Aim 1: Characterize shared decision-making and unmet patient-caregiver dyads needs for patients with diabetes and Alzheimer's Disease and related dementias (ADRD) while using a continuous glucose monitoring (CGM) device. Aim 2: Develop an interactive tool to enhance shared decision-making for diabetes management.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/17/2024
Locations: Eskenazi Health, Indianapolis, Indiana
Conditions: Diabetes, Alzheimer's Disease (Incl Subtypes), Dementia, Hypoglycemia
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Genetic Characterization of Movement Disorders and Dementias
NCT02014246
Recruiting
Background: There are two basic types of movement disorders. Some cause excessive movement, some cause slowness or lack of movement. Some of these are caused by mutations in genes. On the other hand, dementia is a condition of declining mental abilities, especially memory. Dementia can occur at any age but becomes more frequent with age. Researchers want to study the genes of families with a history of movement disorders or dementia. They hope to find a genetic cause of these disorders. This ca... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: National Institute of Aging, Clinical Research Unit, Baltimore, Maryland
Conditions: Dementia, Movement Disorder
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Aging Brain Care Virtual Program
NCT06245499
Recruiting
The program involves a virtual intervention to be delivered by RN or SW care coordinators over one year. Every care partner will receive monthly virtual visits during the first 3 months and then quarterly or more depending on assessed need. The intervention relies on a tailored approach in which patient and caregiver needs are identified during visits using validated assessment tools and addressed with standardized protocols. Protocols include management of behavioral/psychological symptoms of d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Alzheimer Disease
Register for Updates
Alzheimer's Disease Neuroimaging Initiative 4
NCT05617014
Recruiting
Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study has been to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI4 continues the previously funded ADNI1, ADNI-GO, ADNI2, and ADNI3 studies that have combined public/private collaborations between academia and industry to determine the relationships between the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of AD.
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
04/16/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +35 locations
Conditions: Mild Cognitive Impairment, Alzheimer Disease, Dementia
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Patient Priorities Care Among Persons Living With Mild Cognitive Impairment and Dementia
NCT06001775
Recruiting
The goal of this pragmatic, embedded clinical trial is to analyze the implementation of Patient Priorities Care in primary care and geriatrics clinics with patients living with dementia or mild cognitive impairment. This study aims are: demonstrate the feasibility of using the electronic health record to identify a diverse cohort of eligible patient and patient-care partner dyads who will engage in a Patient Priorities Care conversation with a trained facilitator. demonstrate feasibility of pra... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
04/16/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Mild Cognitive Impairment
Register for Updates
Coaching Dementia Caregivers to Master Care-Resistant Behavior
NCT05098652
Recruiting
266 family caregivers will be randomly assigned to either immediate intervention or delayed intervention groups. All caregivers will complete baseline surveys and 3 weeks of daily diaries. The immediate intervention group will receive 12 weeks of CuRB-IT. They will complete 3 rounds of 3-week daily diaries followed by an intermittent survey at 12 week intervals for the next 33 weeks. The delayed intervention group will receive 12 weeks of attention, complete 1 round of 3-week daily diaries follo... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
04/15/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Care-resistant Behavior, Dementia
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PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
NCT04396873
Recruiting
Background: About 5 million adults in the U.S. have Alzheimer s disease or another adult-onset neurodegenerative disorder. Many studies have found that inflammation in the brain contributes to these diseases. Researchers want to find a better way to measure this inflammation. Objective: To learn whether COX-1 and/or COX-2 is elevated in the brains of individuals with neurodegenerative brain disease compared to healthy volunteers. Eligibility: Adults age 18 years and older in good general he... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/13/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Dementia, Alzheimer's Disease, ALS, Parkinson's Disease
Register for Updates
Neurologic Stem Cell Treatment Study
NCT02795052
Recruiting
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. http://mdstemcells.com/nest/
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: MD Stem Cells, Westport, Connecticut +2 locations
Conditions: Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
Register for Updates
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
NCT04337255
Recruiting
To test the effects of a 2- to 3-year intervention of the MIND diet versus usual post-stroke care on cognitive decline, the characteristic feature of dementia, and on brain biomarkers of Alzheimer's Disease (AD) and vascular disease in a Phase Ill randomized controlled trial of 500 patients hospitalized for acute ischemic stroke, aged 55 years or older, and without dementia who are discharged home following hospitalization.
Gender:
All
Ages:
55 years and above
Trial Updated:
04/10/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Cognitive Decline, Dementia, Vascular, Alzheimer Disease, Dementia, Stroke
Register for Updates