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Traumatic Brain Injury Clinical Trials
A listing of 96 Traumatic Brain Injury clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 96
There are currently 96 active clinical trials seeking participants for Traumatic Brain Injury research studies. The states with the highest number of trials for Traumatic Brain Injury participants are Texas, California, Florida and Pennsylvania.
Featured Trial
Paid Clinical Studies Nationwide
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Non-invasive Nerve Stimulation for PTSD and Sleep
Recruiting
In this study, our objective is to determine the effect of two different nerve stimulation types in changing sleep architecture.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/26/2025
Locations: UF Health Jacksonville, Gainesville, Florida +2 locations
Conditions: Post Traumatic Stress Disorder, Traumatic Brain Injury
The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)
Recruiting
There are no therapeutic agents that have been shown to improve outcomes from severe traumatic brain injury (TBI). Critical barriers to progress in developing treatments for severe TBI are the lack of: 1) monitoring biomarkers for assessing individual patient response to treatment; 2) predictive biomarkers for identifying patients likely to benefit from a promising intervention. Currently, clinical examination remains the fundamental tool for monitoring severe TBI patients and for subject select... Read More
Gender:
ALL
Ages:
Between 16 years and 65 years
Trial Updated:
06/25/2025
Locations: UCSD Medical Center - Hillcrest Hospital, San Diego, California +10 locations
Conditions: Traumatic Brain Injury
Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.
Recruiting
This project will examine if computerized cognitive remediation will improve working memory and attention in 25 adults with a mild, moderate, or severe brain injury and compare their cognitive performance to the control group of 25 adults with a mild, moderate, or severe brain injury. The control group will train on computerized tasks of social awareness. Participants in both groups will be assessed prior to training and immediately post-training and one month-post training.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: NYU Langone Health, New York, New York
Conditions: Traumatic Brain Injury
Improving Sleep in Veterans With the Polytrauma Clinical Triad
Recruiting
The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain. Veterans with the PCT are medically complex, often refractory to conventional therapies, and suffer from additional related chronic sequela. Notably, sleep disturbances and cognitive impairment, which the investigators hypothesize are significant contributing factors to these functional impairments and an im... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
06/23/2025
Locations: VA Portland Health Care System, Portland, OR, Portland, Oregon
Conditions: Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery
Recruiting
This study has two main goals: 1) to refine and enhance the R2R-TBI intervention; and 2) to examine the efficacy of the R2R-TBI intervention in a randomized control trial. To achieve the second goal, we will employ a between-groups randomized treatment design with repeated measures at baseline, one-month post-randomization, and at a six-month follow-up. The two conditions will be: a) usual medical care plus access to internet resources regarding pediatric brain injury (Internet Resources Compari... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/20/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Traumatic Brain Injury, Head Injury, Head Injuries, Closed, Brain Hemorrhage, Traumatic, Brain Edema, Intracranial Edema
University of Pittsburgh Brain Health Initiative
Recruiting
This project will define the prevalence of brain health (i.e., normal cognitive, neuromotor, behavioral function) in living professional football retirees and group-matched controls through a comprehensive assessment of clinical, neuroimaging, and biomarker measures.
Gender:
MALE
Ages:
Between 29 years and 59 years
Trial Updated:
06/12/2025
Locations: University of Pittsburgh Department of Neurosurgery, Pittsburgh, Pennsylvania
Conditions: Traumatic Brain Injury
A Pilot Randomized Controlled Trial: CoINTEGRATE
Recruiting
The purpose of this study is to examine the feasibility of comprehensive multimodal individually tailored Cognitive Behavioral Therapy (CBT), Cognitive Rehabilitation Therapy (CRT), and modifiable lifestyle sessions.
The study team hypothesizes that combining evidence-based cognitive and affective therapies with lifestyle modifications is feasible and will improve the community integration (CI) and Quality of life (QoL) in patients with a neurocognitive disorder compared to usual care.
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
06/11/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis, Mild Cognitive Impairment
Intervention to Change Affect Recognition and Empathy
Recruiting
Determine the feasibility, practicality, and early efficacy of a TeleRehab program (ICARE) to improve outcomes for persons with traumatic brain injury (TBI) in recognizing and responding to others' emotions alongside their care partner (CP).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/09/2025
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Traumatic Brain Injury, Concussion, Intermediate, Concussion, Severe, Concussion With LOC 31 to 59 Minutes, Concussion With Brief Loss of Consciousness, Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With Loss of Consciousness, Traumatic Brain Injury With Prolonged Loss of Consciousness, Traumatic Brain Injury (TBI); Concussion, Initial Encounter, Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter, Traumatic Brain Injury With No Loss of Consciousness, Traumatic Brain Injury With Open Intracranial Wound, Traumatic Brain Injury With Moderate Loss of Consciousness
Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression
Recruiting
The purpose of this study is to improve behavior control displayed by persons with traumatic brain injury by assessing effectiveness of treatments for post-TBI irritability and aggression.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/09/2025
Locations: Indiana University and Rehabilitation Hospital of Indiana, Indianapolis, Indiana
Conditions: Traumatic Brain Injury
Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury
Recruiting
The global objective of this study is to establish the safety and investigate the potential treatment effect of an intravenous infusion of HB-adMSCs (Hope Biosciences adipose-derived mesenchymal stem cells) on brain structure, neurocognitive/functional outcomes, and neuroinflammation after traumatic brain injury.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/04/2025
Locations: Memorial Hermann Hospital / UTHealth McGovern Medical School at Houston, Houston,, Texas +1 locations
Conditions: Traumatic Brain Injury
Neurologic Stem Cell Treatment Study
Recruiting
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. http://mdstemcells.com/nest/
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/03/2025
Locations: MD Stem Cells, Westport, Connecticut +2 locations
Conditions: Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder
Recruiting
The purpose of this study is to evaluate the safety and efficacy of individualized, Biometrics-guided Magnetic e-Resonance Therapy (MeRT) treatment of Post-Traumatic Stress Disorder
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/15/2025
Locations: BrainHealth Solutions, Costa Mesa, California +7 locations
Conditions: Postconcussive Symptoms, Traumatic Brain Injury, PostTraumatic Stress Disorder
1 - 12 of 96