The city of Gainesville, Florida, currently has 4 active clinical trials seeking participants for Alzheimer's Disease research studies.
Fasting ENHANCE Pilot Study
Recruiting
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable manner in at risk overweight older adults. Specifically, this study will evaluate whether TRE can improve cognitive and physical function, as well as self-reported sleep, mood, and quality of life, in overweight, older adults (age \> 65 years) who are at high risk of co... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
10/23/2024
Locations: Clinical and Translational Research Building - Institute on Aging Suite, Gainesville, Florida
Conditions: Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease
ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease
Recruiting
The purpose of this study is to evaluate the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's Disease (AD).
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
10/04/2024
Locations: University of Florida Health Shands, Gainesville, Florida
Conditions: Alzheimer Disease
Preventing Alzheimer's With Cognitive Training
Recruiting
Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residentia... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
09/24/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
The Revitalize Study in Older Adults at Risk for Alzheimer's Disease
Recruiting
The goal of this multi-site double blinded randomized sham-controlled Phase II clinical trial is to test a novel, relatively low cost, low risk, and potentially high impact therapeutic intervention in older adults who are at increased risk for Alzheimer's disease. The intervention involves transcranial and intranasal delivery of near infrared (NIR) light via light emitting diodes, aka photobiomodulation. The overall hypothesis, based on animal and pilot studies, is that exposure to NIR stimulati... Read More
Gender:
ALL
Ages:
Between 65 years and 89 years
Trial Updated:
05/07/2024
Locations: University of Florida McKnight Brain Institute, Gainesville, Florida
Conditions: Cognitive Aging, Alzheimer Disease, Protection Against