There are currently 2029 clinical trials in Chicago, Illinois looking for participants to engage in research studies. Trials are conducted at various facilities, including Northwestern University, Rush University Medical Center, University of Chicago and University of Chicago Comprehensive Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Phase 2 Study of MZE829 in Adults with APOL1 Kidney Disease
NCT06830629
Recruiting
This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/12/2025
Locations: Research by Design, LLC, Chicago, Illinois
Conditions: Proteinuric Kidney Disease
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Follow-up Visit of High Risk Infants
NCT00009633
Recruiting
The NICHD Neonatal Research Network's Follow-Up study is a multi-center cohort in which surviving extremely low birth-weight infants born in participating network centers receive neurodevelopmental, neurosensory and functional assessments at 22-26 months corrected age (Infants born prior to July 1, 2012 were seen at 18-22 months corrected age). Data regarding pregnancy and neonatal outcome are collected prospectively. The goal is to identify potential maternal and neonatal risk factors that may... Read More
Gender:
ALL
Ages:
Between 18 months and 26 months
Trial Updated:
02/11/2025
Locations: Northwestern Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
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Generic Database of Very Low Birth Weight Infants
NCT00063063
Recruiting
The Generic Database (GDB) is a registry of very low birth weight infants born alive in NICHD Neonatal Research Network (NRN) centers. The GDB collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Data are analyzed to find associations and trends between baseline information, treatments, and infant outcome, and to develop future NRN trials.
Gender:
ALL
Ages:
14 days and below
Trial Updated:
02/11/2025
Locations: Northwestern Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
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Phase I Study of RiMO-301 With Radiation in Advanced Tumors
NCT03444714
Recruiting
This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with radiation in patients with advanced tumors. A single escalation dose of RiMO-301 is intratumorally injected in a 3 + 3 study design to identify the recommended dose and dosing volumes. Condition or Disease: Patient with advanced tumor which is clinically accessible for intratumoral injection Intervention/Treatment: Drug - RiMO-301 Radiation - Radiotherapy Phase: Phase 1
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: University of Illinois at Chicago, Chicago, Illinois +1 locations
Conditions: Advanced Tumors
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Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis
NCT05427695
Recruiting
The purpose of this randomized study will be to determine whether topical probiotic sinus irrigations are more effective compared to saline sinus irrigation controls in the treatment of active CRS in patients who have had prior sinus surgery based on subjective and objective outcome measures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: University of Illinois Hospitals & Health Sciences System, Chicago, Illinois
Conditions: Chronic Rhinosinusitis (Diagnosis)
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Study of RiMO-301 and Radiotherapy With PD-1 Inhibitor for the Treatment of Head-Neck Cancer
NCT05838729
Recruiting
This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with hypofractionated radiation and a PD-1 Inhibitor in patients with unresectable, recurrent or metastatic head-neck cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Head Neck Cancer, Intratumoral Injection
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Families Filming Infants Learning Movement
NCT06278961
Recruiting
The study objective is to improve accuracy in the early detection of neurodevelopmental impairment, especially CP, by evaluating the timepoint (in weeks post term age) that the Prechtl GMA is most useful for prediction of neurodevelopmental impairment at two years of age in children with and without medical complexity. The study team plans to recruit 100 healthy, term-born infants and 250 infants at risk of developing CP for a total of 350 enrolled infants.
Gender:
ALL
Ages:
Between 10 weeks and 20 weeks
Trial Updated:
02/11/2025
Locations: Feinberg School of Physical Therapy and Human Movement Sciences, Chicago, Illinois
Conditions: Infant Development, Cerebral Palsy, Motor Disorders, Neurological Disorder
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Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
NCT06317701
Recruiting
The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism. The study team will also determine if the treatment of Obstructive sleep apnea (OSA) by (hypoglossal nerve stimulation) HGNS will alter predictors of cardiovascular outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: The University of Chicago, Chicago, Illinois
Conditions: Obstructive Sleep Apnea
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Dysbiosis & Long COVID
NCT06825819
Recruiting
The SARS-CoV-2 virus causes COVID-19, which ranges from mild initial symptoms to severe multi-organ dysfunction. While some patients recover to their baseline states, others develop a long COVID, or post-acute sequelae of SARS-CoV-2 (PASC) consisting of symptoms persisting \>2-6 months post-infection. PASC symptoms include post-exertional malaise, fatigue, and heart palpitations as well as incident GI disorders, cognitive dysfunction, and arthritis. Based on prevalence/incidence studies, it is e... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/11/2025
Locations: The University of Chicago, Chicago, Illinois
Conditions: COVID-19
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Surgical or Medical Treatment
NCT04128995
Recruiting
This study will test the hypothesis that metabolic bariatric surgery will be more effective at providing durable glycemic control and reduce co-morbidities than intensive medical therapy in youth with type 2 diabetes.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
02/10/2025
Locations: Lurie Children's Hospital, Chicago, Illinois
Conditions: Diabetes Mellitus, Type 2, Pediatric Obesity, Bariatric Surgery Candidate
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A Clinical Trial in Healthy Volunteers and Volunteers with Recurrent Genital Herpes to Study the Safety, Tolerability, and Immune Responses After Vaccination with an Investigational Vaccine Designed to Prevent Genital Herpes Lesions
NCT05432583
Recruiting
This exploratory trial will have three parts. Part A is a dose escalation part, Part B is an expanded safety and dose evaluation part, and Part C is a safety and immunogenicity evaluation part in individuals with recurrent HSV-2 genital herpes. Part A will focus on the safety evaluations, and in addition, vaccine-induced immune responses (specifically neutralizing antibodies) will also be analyzed to assess if there is a dose-response. Part B of the trial will expand the safety characterizatio... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/10/2025
Locations: Great Lakes Clinical Trials - Flourish Research, Chicago, Illinois
Conditions: Genital Herpes Simplex Type 2
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Point-of-Care Echocardiography in Patients with Known or Suspected Aortic Stenosis
NCT06717373
Recruiting
This is a prospective clinical trial intended to capture echocardiographic images in patients clinically indicated for an echocardiographic examination using an additional Point of Care Ultrasound device . The images collected will be used to test and possibly validation an AI base Aortic Valve Stenosis algorithm
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Patients with an Indication for an Echocardiographic Examination with Suspicion of Valcular Heart Disease
Register for Updates