There are currently 2014 clinical trials in Chicago, Illinois looking for participants to engage in research studies. Trials are conducted at various facilities, including Northwestern University, Rush University Medical Center, University of Chicago and University of Chicago Comprehensive Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Effect of IBD Flares on Serum PSA
NCT03558048
Recruiting
This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD by identifying pitfalls in prostate cancer screening for this population and help to stratify and understand the effect IBD has on the prostatic milieu. By optimizing how men with IBD are scree... Read More
Gender:
MALE
Ages:
Between 40 years and 69 years
Trial Updated:
04/22/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Inflammatory Bowel Diseases, Prostate Cancer
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Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus
NCT05056051
Recruiting
Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable. Progression of BE to esophageal cancer is still common due to missed diagnosis of Barrett's esophagus recurrence following treatment. Wide-Area Trans-Epithelial Sampling (WATS-3D) is a new technology that uses brush sampling to examine larger areas of the esophagus as compared to conven... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Barrett Esophagus, Esophageal Cancer
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Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality
NCT06191289
Recruiting
This within-person, crossover, 2-condition, placebo-controlled study compares the impact of two perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent suicide attempt. The two conditions are (1) perimenstrual administration of estradiol and (2) natural perimenstrual withdrawal from estradiol during placebo.
Gender:
FEMALE
Ages:
Between 20 years and 40 years
Trial Updated:
04/22/2024
Locations: University of Illinois Neuropsychiatric Institute, Chicago, Illinois
Conditions: Suicide
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Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
NCT06374537
Recruiting
This research is being done to better understand the impact of the use of a specific physical activity training program (GH Method) in dialysis/kidney disease patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Frailty, Pain, Chronic, Dialysis; Complications, Kidney Diseases
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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
NCT01656603
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois +1 locations
Conditions: Infusion Reactions
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PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.
NCT05489822
Recruiting
In accordance with the European Medical Device Regulation MDR 2017/745/EU, the legal manufacturers of medical devices are obliged to evaluate medical devices with regard to their clinical performance and safety. The VERTICALE® Cervical System is intended for immobilization and stabilization of spinal segments of the craniocervical junction (occipital-C2), subaxial cervical spine (C3-C7) and upper thoracic spine (T1-T3). Primary Objective: To assess the functional outcome and clinical benefit... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University of Illinois Hospital and Health Sciences System - UI Health, Chicago, Illinois
Conditions: Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2
NCT05555589
Recruiting
The objective of this study is to compare the safety and efficacy of RGN-259 to placebo for the treatment of Neurotrophic Keratopathy (NK)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Northwestern, Chicago, Illinois
Conditions: Neurotrophic Keratopathy
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Acute Intermittent Hypoxia in Traumatic Brain Injury
NCT04890639
Recruiting
This study is designed to answer questions related to safety and preliminary efficacy of Acute Intermittent Hypoxia (AIH) in Traumatic Brain Injury (TBI) survivors. First, we aim to establish whether brief reductions in inhaled oxygen concentration can be safely tolerated in TBI survivors. Second, we aim to establish whether there are any effects of AIH on memory, cognition, and motor control. Participants will be monitored closely for any adverse events during these experiments. Data will be an... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/16/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Brain Injuries, Traumatic
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Knee Arthroplasty Activity Trial
NCT04107649
Recruiting
Total knee replacement (TKR) is a common and costly procedure widely used to relieve pain and improve function in patients with symptomatic advanced knee osteoarthritis (OA). As of 2013, the annual incidence of TKR was over 680,000 surgeries and annual costs exceeded $11 billion. Growing evidence suggests that while pain and functional status improve following TKR, physical activity (PA) typically does not surpass pre-TKR levels. Engagement in PA can meaningfully improve quality of life (QoL), p... Read More
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
04/15/2024
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Knee Osteoarthritis, Total Knee Replacement
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Quality of Pediatric Resuscitation in a Multicenter Collaborative
NCT02708134
Recruiting
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
04/12/2024
Locations: Comer Children's Hospital, Chicago, Illinois +1 locations
Conditions: Cardiac Arrest, Cardiopulmonary Arrest
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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
NCT05230173
Recruiting
The purpose of this study is to compare the effectiveness and safety of a strategy of switching to an alternative targeted immunomodulator (TIM) therapy to treat to a target of endoscopic remission, versus continuing index TIM in patients with inflammatory bowel disease (IBD) (Crohn's disease or ulcerative colitis \[UC\]) in symptomatic remission with moderate to severe endoscopic inflammation despite optimization of index TIM in a real-world setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Ulcerative Colitis, Crohn Disease
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Lurie Children's Hospital-Chicago, Chicago, Illinois +2 locations
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
Register for Updates