There are currently 574 clinical trials in Louisville, Kentucky looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Louisville, Jewish Hospital, Norton Cancer Institute and Norton Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Connect® Myeloid Disease Registry
NCT01688011
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Baptist Health Systems, Inc., DBA Baptist, Louisville, Kentucky
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
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Neoadjuvant Combination Immunotherapy for Stage III Melanoma
NCT03842943
Recruiting
Determine safety and efficacy of pre-operative combination immunotherapy with Talimogene Laherparepvec (T-VEC)/Pembrolizumab given prior to complete lymph node dissection in resectable stage 3 cutaneous melanoma with clinically apparent lymph node metastases.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Cutaneous Melanoma
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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
NCT01656603
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: James Graham Brown Cancer Center, Louisville, Kentucky
Conditions: Infusion Reactions
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Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)
NCT04816604
Recruiting
This open-label extension study will evaluate the long-term effects of GB002 (seralutinib) in subjects who previously participated in a GB002 PAH study.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/16/2024
Locations: Norton Pulmonary Specialists, Louisville, Kentucky
Conditions: Pulmonary Arterial Hypertension
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Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft
NCT05484492
Recruiting
The primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs. synthetic calcium phosphosilicate (CPS) putty alloplast graft utilization in socket preservation procedures. A regenerative tissue matrix membrane will be used to cover each graft lying below the flap.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Alveolar Bone Resorption
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Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative
NCT05565079
Recruiting
24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical attachment levels, amount of keratinized tissue width, and soft tissue thickness.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Recession, Gingival
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Norton Children's Hospital, Louisville, Kentucky
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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Guided Bone Regeneration With and Without the Use of Intra-marrow Penetrations
NCT06353399
Recruiting
The primary aims of this study are to compare, after 6 months, the clinical and histologic results of intra-marrow penetrations vs no intra-marrow penetrations when performing guided bone regeneration procedures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/07/2024
Locations: University of Louisville, Louisville, Kentucky +1 locations
Conditions: Ridge Augmentation
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PDA Occlusion Using NIRS
NCT06359522
Recruiting
Our study will be a prospective observational study of all patients in the Norton Children's Hospital NICU (Neonatal Intensive Care Unit) who undergo a transcatheter PDA occlusion or medical closure of PDA to compare the two populations regarding changes in organ perfusion determined by using NIRS monitoring to follow the regional saturation of oxygen (rSO2) of the cerebral and renal regions. We suspect that medical treatment will have no significant change in rSO2 as described in previous liter... Read More
Gender:
ALL
Ages:
Between 0 months and 3 months
Trial Updated:
04/05/2024
Locations: Norton Children's Hospital, Louisville, Kentucky
Conditions: Organ Perfusion Determined by Using NIRS Post Transcatheter PDA Occlusion or Medical Closure of PDA
Register for Updates
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
NCT03645928
Recruiting
A prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL LN-144 (Lifileucel)/LN-145 in combination with checkpoint inhibitors or TIL LN-144 (Lifileucel)/LN-145/LN-145-S1 as a single agent therapy.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
04/04/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Metastatic Melanoma, Squamous Cell Carcinoma of the Head and Neck, Non-small Cell Lung Cancer
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Gastroparesis Outcome Longitudinal Database Enrolled Numerically
NCT03876288
Recruiting
GOLDEN is a longitudinal database of patients with the symptoms (Sx) of gastroparesis (Gp) who were seen and recorded at the University of Louisville from 2012 and is ongoing. Patients are enrolled and followed by sequential numbers and may include legacy patients seen at other centers by some of the same team and who are reported as part of the series. Outcome relate to patients Sx, survival, quality of life and other measures as detailed below, over time, regardless of whether any treatment wa... Read More
Gender:
ALL
Ages:
All
Trial Updated:
04/04/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Gastroparesis
Register for Updates
IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy
NCT04208828
Recruiting
Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions/ Some of these patients have serologic and/or endo organ abnormalities and findings consistent with autoimmune neuropathies, primarily involving the GI tract. These disorders have been known as autoimmune gastrointestinal neuropathies (GAIN) or also as autoimmune gastrointestinal dysmotility (AGID), among other terms. Some patients... Read More
Gender:
ALL
Ages:
Between 12 years and 90 years
Trial Updated:
04/04/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Gastrointestinal Motility Disorder, Gastroparesis, Neuropathy
Register for Updates