Louisiana is currently home to 894 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Orleans, Baton Rouge, Shreveport and Metairie. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
EMPOWER 3: Improving Palliative Care Health Literacy and Utilization
Recruiting
Through this award, Michael Hoerger, PhD, MSCR, a psychologist at the Tulane Cancer Center in Louisiana, will lead a study called EMPOWER 3 designed to test an educational intervention to help patients understand palliative care, use it, and feel better emotionally and physically. Participants will be adults with serious cancer diagnoses. Participants will be randomized into two groups. Patients in the control group will get enhanced usual care, meaning standard cancer care and several additiona... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: University Medical Center, New Orleans, Louisiana
Conditions: Cancer, Neoplasm Malignant
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: University Medical Center, New Orleans, Louisiana
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline
Recruiting
The study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP \<120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in primary care. The proposed study will generate urgently needed data on effective, adoptable, and equitable intervention strategies to reduce blood pressure-related cognitive decline in low- income and minority populations. If proven effective, the implementation strategy for... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/13/2024
Locations: Tulane University, New Orleans, Louisiana
Conditions: Hypertension, Cognitive Decline
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
Recruiting
A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at high risk for COPD exacerbations.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/06/2024
Locations: Ochsner Medical Center, New Orleans, Louisiana
Conditions: Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
Recruiting
This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Ochsner Clinic Foundation, New Orleans, Louisiana
Conditions: Hiv
Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
Recruiting
The goal of this clinical trial is to quantify the effects of aerobic exercise training compared to attention control on intermuscular adipose tissue in colorectal cancer survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Colonic Neoplasms, Rectal Neoplasms
Modulating Energy Density in Time-Restricted Eating
Recruiting
The goal of this randomized controlled trial is to test the effect of time-restricted eating (14-hour fast, 10-hour eating window) of a low-energy dense diet (reduced calories per gram of food) in older adults with obesity and insulin resistance. The study aims to determine if modulating the energy density of the diet reduces: 1. Insulin resistance and 2. Body weight. Researchers will compare the groups: 1. Following time-restricted eating and given a diet reduced in energy density or 2. Foll... Read More
Gender:
ALL
Ages:
Between 50 years and 75 years
Trial Updated:
05/31/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Insulin Resistance, Body Weight
Registry Study for Radiation Therapy Outcomes
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: Willis-Knighton Cancer and Proton Therapy Center, Shreveport, Louisiana
Conditions: Neoplasms
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Recruiting
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Colonic Neoplasms
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: Willis-Knighton Medical Center, Shreveport, Louisiana
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
A Novel Therapeutic Treatment of Pyoderma Gangrenosum
Recruiting
Pyoderma gangrenosum is a chronic debilitating ulcerative neutrophilic condition usually affecting the skin. The pathogenesis of pyoderma gangrenosum is poorly understood. Pyoderma gangrenosum has been estimated to have an incidence rate of 3-10 per million populations per year. Mortality estimates range up to 30%. The non-healing wounds present a significant social and economic burden on affected patients. We hypothesize that EpiFix (dehydrated human amnion/chorion membrane) will be beneficial... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: LSU Healthcare Network Clinic, Metairie, Louisiana
Conditions: Pyoderma Gangrenosum
Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery
Recruiting
This study is a prospective randomized controlled trial comparing the clinical outcomes of bioabsorbable screws to conventional metal screws in pediatric patients (aged 0 to 18) undergoing surgical fixation for trauma or elective procedures. Conducted by the pediatric orthopedic department at Children's Hospital New Orleans, the study aims to evaluate the effectiveness of these screws in bone healing over key post-operative intervals (6 weeks, 6 months, and 1 year). It seeks to determine if bioa... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
05/20/2024
Locations: Children's Hospital New Orleans, New Orleans, Louisiana
Conditions: Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction