There are currently 1568 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation
Recruiting
Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and the potential for developing a safer endobronchial mucosal biopsy format.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2024
Locations: University of Maryland School of Medicine, Baltimore, Maryland
Conditions: Lung Transplant Rejection
Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment
Recruiting
This study seeks to improve the treatment of chronic pain in people who are taking buprenorphine (also known as Suboxone, Subutex, Zubsolv). The research study is testing two different interventions along with usual clinical care: 1. Pain Self-Management (PSM): an educational program in which individuals with chronic pain work with a trained pain coach and a pain peer to explore strategies to effectively manage the daily problems that arise from chronic pain. 2. Patient-Oriented Dosing (POD):... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2024
Locations: Outpatient Addiction Treatment Services (OATS), Baltimore, Maryland +2 locations
Conditions: Opioid Use Disorder, Chronic Pain
Phase I Study of ICP-332 in Healthy Subjects
Recruiting
A multiple ascending dose phase I study of ICP-332 in healthy subjects
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/31/2024
Locations: Pharmaron CPC Inc., Baltimore, Maryland
Conditions: Healthy Subjects
Multicenter HomeVENT: Home Values and Experiences Navigation Track
Recruiting
This is a multicenter study to test a decision-making support process for families and clinicians facing decisions about chronic home ventilation for a child. The investigators hypothesize that the intervention will increase family preparedness for decision-making and will improve clinician-family shared-decision making. Half of families will be assigned to "usual care" arm and half to the "intervention" arm. Intervention families will view the study website with study staff and will answer ques... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/31/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Pediatric ALL, Respiratory Insufficiency, Communication
Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance
Recruiting
Delta-8-THC is an isomer of delta-9-THC that has become widely available due to the legalization of hemp and its derivatives. Very little controlled research has been conducted with delta-8-THC and some research suggests it produces similar effects to delta-9-THC, albeit at lower potency. The present study will evaluate the dose effects of delta-8-THC, compared with delta-9-THC, on simulated driving performance, field sobriety tests, cognitive performance, and biomarkers of exposure to cannabino... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/30/2024
Locations: Johns Hopkins Behavioral Pharmacology Research Unit, Baltimore, Maryland
Conditions: Cannabis
Alcohol Research in HIV: Relapse Prevention
Recruiting
3-arm type 1 pilot implementation-efficacy trial for people with alcohol use disorders to examine the preliminary effectiveness and feasibility of an adapted 2-session, computerized and person delivered relapse prevention intervention.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: HIV, Alcohol Use Disorder
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
Recruiting
This study aims to determine whether a 6-month multilevel intervention involving problem-solving training, exercise training and support from community health workers is more effective in improving outcomes for individuals with low socioeconomic status, type 2 diabetes, obesity, and early cardiac dysfunction than receiving education and access to a community exercise facility.
Gender:
ALL
Ages:
Between 30 years and 70 years
Trial Updated:
07/29/2024
Locations: Johns Hopkins Center for Health Equity, Baltimore, Maryland
Conditions: Type2diabetes, Heart Failure, Obesity
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I or bipolar II disorder as confirmed by Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL), according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5).
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
07/26/2024
Locations: Clinical Site, Baltimore, Maryland
Conditions: Bipolar Depression
Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease
Recruiting
Cardiac catheterization with invasive coronary angiography is the gold standard for determining the presence or absence of significant coronary heart disease (CHD). However, cardiac catheterization is costly and, as an invasive procedure, it is associated with some risk of adverse events, rarely even stroke, myocardial infarction, or death. Recent advances in multi-detector computed tomography angiography (CTA) have allowed rapid, noninvasive coronary artery imaging in patients with suspected CH... Read More
Gender:
ALL
Ages:
Between 45 years and 85 years
Trial Updated:
07/26/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Coronary Artery Disease
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
Recruiting
Iadademstat is being studied as a treatment for subjects with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+). During the trial, iadademstat will be given in combination with gilteritinib, a drug that is already approved to treat patients with FLT3-mutated R/R AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/26/2024
Locations: The John Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Ulcerative Colitis
Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
Recruiting
The goal of this clinical trial is to learn about the action of Imdusiran (AB-729) in the liver of people with chronic hepatitis B. The main questions it aims to answer are: * how well is it working in the liver * how does Imdusiran affect the hepatitis B virus Participants will receive injections of Imdusiran, one injection every 8 weeks, for a total of 4 doses. They will also undergo 2 liver biopsies: one with the first dose of Imdusiran, and the second 8 weeks after the last dose of Imdusir... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland
Conditions: Chronic Hepatitis B