There are currently 1543 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
GammaPod Dose Escalation Radiation for Early Stage Breast Cancer
Recruiting
The GammaPod machine was made by Xcision Medical Systems and is already FDA cleared to deliver focused radiation within the breast. Unlike current radiation machines, the GammaPod was designed specifically for treating breast cancer. The GammaPod can pinpoint radiation to the tumor bed in the breast which lowers the amount of radiation to nearby tissues. The machine uses a breast cup system to hold the breast in place for the treatment. This breast cup system was tested at MSGCCC (Marlene Stewar... Read More
Gender:
FEMALE
Ages:
45 years and above
Trial Updated:
11/25/2024
Locations: UMMC, Baltimore, Maryland
Conditions: Breast Cancer
Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention
Recruiting
Multiple studies have demonstrated oral suppressive antibiotic therapy (SAT), after intravenous antibiotics, maximizes reoperation-free survival of total joint arthroplasty (TJA) debridement, antibiotics, and implant retention (DAIR) for acute periprosthetic joint infection (PJI). However, little is known regarding sequelae of SAT after DAIR for PJI. Prior studies have small or heterogeneous patient cohorts, variable antibiotic regimens, arrive at disparate conclusions, and do not establish anti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/23/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Periprosthetic Joint Infection, Antibiotic Suppression
Is Physical Therapy Clearance Before Arthroplasty Home Discharge Necessary?
Recruiting
Conventionally, physical therapy (PT) clearance is sought before total joint arthroplasty (TJA) discharge. However, PT staffing limitations may preclude same-day discharge in patients having surgery late in the day. Failed same-day discharge in eligible TJA patients results in unnecessary hospital bed occupancy, which increases costs, limits operating room throughput for patients requiring inpatient admission, and introduces risks associated with longer length-of-stay. In collaboration with an... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/23/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Physical Therapy, Total Joint Arthroplasty, Same-day Discharge
Targeting Emotion Dysregulation to Reduce Suicide in People with Psychosis
Recruiting
People with psychotic disorders are excluded from most suicide-focused clinical trials despite incredibly high rates of completed suicide, and interventions that have been tested for this population have shown limited impact on suicide. Emotion dysregulation is a significant suicidogenic factor that is understudied in people with psychotic disorders. The investigators propose to implement and evaluate an intervention targeting emotion dysregulation in people with psychotic disorders while employ... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Psychosis, Suicide
Development and Evaluation of a PrEP Decision Aid for Women Seeking Domestic Violence Services in Baltimore
Recruiting
This study is designed to develop and test an individual decision aid for pre-exposure prophylaxis (PrEP) tailored to Black women who have been exposed to intimate partner violence and are working with a domestic violence service provider. three different ways of delivering the tailored decision aid are being tested: 1) as an individual tool; or 2) as a shared decision-making tool with a domestic violence advocate; as compared to generalized information. The goal of decision aid will be to addre... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Springboard Community Services - Baltimore City Office, Baltimore, Maryland
Conditions: HIV, Violence, Gender-Based, Pre-Exposure Prophylaxis
Enhancing Care & Outcomes for Patients During the First Postpartum Year
Recruiting
The United States is in the midst of a maternal mortality and morbidity crisis, with more than half of maternal deaths occurring within the first postpartum year. Patients with hypertensive disorders of pregnancy (HDP) and diabetes have been found to be particularly high-risk, as they have a significantly increased risk for the development of cardiovascular disease in the long-term postpartum period. Traditionally, postpartum care has consisted of a single office visit at six weeks postpartum. R... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Postpartum Period, Pregnancy, Hypertension, Pregnancy Induced
International Registry for Men With Advanced Prostate Cancer (IRONMAN)
Recruiting
Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingd... Read More
Gender:
MALE
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Prostate Cancer
Study of SX-682 Alone and in Combination with Oral or Intravenous Decitabine in Subjects with Myelodysplastic Syndrome
Recruiting
This study will determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and recommended Phase 2 dose (RP2D) of SX-682 in the treatment of patients with Myelodysplastic Syndromes (MDS).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland
Conditions: Myelodysplastic Syndromes
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
Recruiting
The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of allogeneic bone marrow-derived MSCs in patients with nonhealing epitheliopathy (IRB Protocol 2020-0334). In the present study, we want to study the efficacy of this treatment on chronic epitheliopathies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: University of Maryland at Baltimore, Baltimore, Maryland
Conditions: Corneal Ulcer
Pictographs for Preventing Wrong-Patient Errors in NICUs
Recruiting
Newborns in the neonatal intensive care unit (NICU) are at high risk for wrong-patient errors. Effective 2019, The Joint Commission requires that health systems adopt distinct methods of newborn identification as part of its National Patient Safety Goals. Displaying patient photographs in the electronic health record (EHR) is a promising strategy to improve identification of children and adults, but is unlikely to be effective for identifying newborns. This study assesses the use of Pictographs... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Medical Errors, Electronic Medical Records
Fabry Disease Registry & Pregnancy Sub-registry
Recruiting
The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary objectives of the Registry are: * To enhance the understanding of the variability, progression, and natural history of F... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: John Hopkins- Site Number : 840044, Baltimore, Maryland
Conditions: Fabry Disease
Abatacept in Immune Checkpoint Inhibitor Myocarditis
Recruiting
The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurrence of cardiovascular death, non-fatal sudden cardiac arrest, cardiogenic shock, significant ventricular arrythmias, significant bradyarrythmias, or incident heart failure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Myocarditis Acute, Cancer