There are currently 1574 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Effects of Simvastatin on Uterine Leiomyoma Size
NCT03400826
Recruiting
The study aims to study the effect of simvastatin on the size of uterine fibroids.
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
07/10/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Fibroid Uterus, Fibroid Tumor, Leiomyoma, Fibromyoma, Leiomyoma, Uterine
Register for Updates
Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI
NCT05671874
Recruiting
The goal is to pilot test a highly accessible, web-based, pragmatic, scalable intervention to overcome ongoing problems with high stakes decision-making by surrogate decision-makers of patients in ICUs with severe acute brain injury (SABI), including those with moderate-severe traumatic brain injury, large hemispheric acute ischemic stroke and intracerebral hemorrhage.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland +1 locations
Conditions: Hemorrhagic Stroke, Intracerebral, Acute Ischemic Stroke, Traumatic Brain Injury
Register for Updates
The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry
NCT02346435
Recruiting
Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, \<=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/08/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Kidney Neoplasm
Register for Updates
Luteolin for the Treatment of People With Schizophrenia
NCT05204407
Recruiting
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory properties. The purpose of this study is to determine if luteolin helps improve symptoms of schizophrenia.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/08/2024
Locations: Maryland Psychiatric Research Center, Baltimore, Maryland
Conditions: Schizophrenia, Schizoaffective Disorder
Register for Updates
Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention
NCT06143852
Recruiting
The investigators will be randomizing 150 college student participants with high levels of social media use into either a 1) control condition (no intervention), a 2) mindfulness meditation cognitive intervention, or 3) a social media reduction + exercise replacement intervention. Participants complete intervention activities daily for one week. The investigators will collect self-report and behavioral measures of social media use and related psychological constructs at three time points: baseli... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/04/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Social Media Addiction, Depression, Anxiety, Well-Being, Psychological
Register for Updates
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
NCT03891160
Recruiting
The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to study the correlation of having a 3D printed model with improvement in patient outcomes and compare those with patients who have had a VAD placement without a 3D model.
Gender:
ALL
Ages:
All
Trial Updated:
07/03/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Congenital Heart Disease
Register for Updates
Robot Aided Rehabilitation - Intervention
NCT02359253
Recruiting
Sensorimotor impairments following stroke often involve complex pathological changes across multiple joints and multiple degrees of freedom of the arm and hand, thereby rendering them difficult to diagnose and treat. The objective of this study is to evaluate multi-joint neuromechanical impairments in the arm and hand, then conduct impairment-specific treatment, and determine the effects of arm versus hand training and the effects of passive stretching before active movement training.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/02/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Stroke
Register for Updates
Robot Aided Rehabilitation - Multi-joint Evaluations
NCT02359812
Recruiting
Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and proprioceptive acuity will be present among multiple degree of freedom in the upper limb. The stiffness and spasticity will increase with time post-stroke. The objective of this study is to quantify the progression throughout the arm and hand during recovery from stroke. The inves... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/02/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Stroke
Register for Updates
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
NCT03391778
Recruiting
This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.
Gender:
ALL
Ages:
All
Trial Updated:
07/02/2024
Locations: ADP Investigational Site, Baltimore, Maryland
Conditions: Neoplasms
Register for Updates
Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer
NCT05312671
Recruiting
This is a single arm, Phase II trial involving the use of atezolizumab plus platinum and etoposide for patients with locally advanced urothelial cancer. The primary goal of this trial is to assess the pathologic complete response rate at cystectomy in patients after being treated with a combination therapy of atezolizumab, platinum, and etoposide.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2024
Locations: Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer, Urothelial Carcinoma Bladder
Register for Updates
Investigation on the Cortical Communication (CortiCom) System
NCT03567213
Recruiting
The CortiCom system consists of 510(k)-cleared components: platinum PMT subdural cortical electrode grids, a Blackrock Microsystems patient pedestal, and an external NeuroPort Neural Signal Processor. Up to two grids will be implanted in the brain, for a total channel count of up to 128 channels, for six months. In each participant, the grid(s) will be implanted over areas of cortex that encode speech and upper extremity movement.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
07/01/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Tetraplegia, Locked-in Syndrome, Brainstem Stroke, Amyotrophic Lateral Sclerosis
Register for Updates
Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug
NCT04299490
Recruiting
The overall goal of this project is to determine whether common sleep disturbance patterns, sleep continuity disturbance (SCD) and Sleep Fragmentation (SF), alter cerebral study drug receptor availability, drug-based analgesia, and drug abuse liability. The investigators specifically aim to: 1) evaluate whether experimental SCD and/or SF alter resting or pain-evoked receptor binding potential in brain regions associated with pain inhibition; 2) examine whether SCD and/or SF alters the analgesic... Read More
Gender:
ALL
Ages:
Between 18 years and 48 years
Trial Updated:
07/01/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Sleep Disorder, Healthy
Register for Updates