There are currently 1574 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles
NCT05602649
Recruiting
This study will examine the pharmacokinetics and pharmacodynamics of delta-9-tetrahydrocannabinol (THC)-infused chocolates, gummies, and drinks. Healthy adults (N=40) will complete 9 drug administration sessions, including an overnight stay prior to each session. Participants will consume THC containing products in a fasted state; following drug administration, the participants will complete cognitive and psychomotor tasks, subjective assessments, have blood collected, and vital signs monitored.
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
07/16/2024
Locations: Johns Hopkins Behavioral Pharmacology Research Unit, Baltimore, Maryland
Conditions: Cannabis Use
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Using Technology to Track Pain and Pain-related Outcomes
NCT04267588
Recruiting
Persistent pain is a public health epidemic. The current protocol seeks to develop technology to aid patients' tracking of patients' pain, medications and pain-related variables. The investigators seek to talk with patients in co-investigator's clinic to solicit feedback, as well as pilot test the technology with pain patients.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
07/15/2024
Locations: Behavioral Medicine Research Lab, Baltimore, Maryland
Conditions: Pain, Chronic
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A Study of Standard Drugs for Mycobacterium Avium Complex
NCT04287049
Recruiting
To assess the early bactericidal activity of Azithromycin 250mg by mouth daily over the first 14 days of treatment for Mycobacterium avium complex (MAC) lung disease.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/15/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Mycobacterium Avium Complex
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Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
NCT05141513
Recruiting
This study is designed to investigate the safety of intraoperative radiation therapy (IORT) in patients with localized pancreatic cancer undergoing surgical resection after neoadjuvant chemotherapy and stereotactic body radiation therapy (SBRT).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pancreatic Cancer
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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow
NCT04254185
Recruiting
This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if one surgery is better than the other to alleviate symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Johns Hopkins University, Baltimore, Maryland +1 locations
Conditions: Neuropathy Ulnar
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Gerofit and Cognition
NCT06107842
Recruiting
Over 50% of the Veterans enrolled for VA health care are over the age of 65. Dementia prevalence increases with age, and with the increase in the population of people ages 65 and older, the total number of people with dementia is also increasing. Older Veterans often have comorbid PTSD, major depression and traumatic brain injury so that they are at 2 to 5 times the risk for cognitive impairment and dementia compared to the general population. There is evidence that exercise interventions in sed... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
07/11/2024
Locations: Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland
Conditions: Aging, Cognitive Impairment, Physical Activity
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Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol
NCT03997370
Recruiting
This trial studies how well iohexol works in helping doctors calculate the dose of carboplatin given to patients with cancer. Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Understanding how to best calculate the dose of carboplatin given to patients with cancer may help doctors learn how to improve the use of carboplatin in the future.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Conditions: Malignant Solid Neoplasm
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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT05646316
Recruiting
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera to look for cancer that may have spread to nearby... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland
Conditions: Stage I Uterine Corpus Cancer AJCC v8
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Optic Nerve Head Strain as Biomarker for Glaucoma
NCT06240312
Recruiting
The investigators will test the hypothesis that images of the optic nerve head taken a 2 different eye pressures will yield strain estimates that are predictive of the course of glaucoma.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
07/11/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Glaucoma, Open-Angle
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Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial
NCT06308107
Recruiting
This study aims to confirm the safety and efficacy of diazoxide as an additive to hyperkalemic cardioplegia in patients undergoing cardiac surgery with cardiopulmonary bypass. The investigators hypothesize that diazoxide combined with hyperkalemic cardioplegia provides superior myocardial protection and reduced myocardial stunning compared with standard cardioplegia alone. Thirty patients will receive treatment. Safety will be assessed by comparing mean arterial blood pressure measurements, gluc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Myocardial Stunning
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Effects of Simvastatin on Uterine Leiomyoma Size
NCT03400826
Recruiting
The study aims to study the effect of simvastatin on the size of uterine fibroids.
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
07/10/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Fibroid Uterus, Fibroid Tumor, Leiomyoma, Fibromyoma, Leiomyoma, Uterine
Register for Updates
Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in Mild Cognitive Impairment (MCI)
NCT04765137
Recruiting
The purpose of this study is to evaluate the effect of atorvastatin on brain vessel reactivity and with it on blood flow in people with mild cognitive impairment.
Gender:
ALL
Ages:
Between 60 years and 95 years
Trial Updated:
07/10/2024
Locations: Johns Hopkins University, Bayview Medical Center, Baltimore, Maryland
Conditions: Mild Cognitive Impairment
Register for Updates