There are currently 1555 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Luteolin for the Treatment of People With Schizophrenia
NCT05204407
Recruiting
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory properties. The purpose of this study is to determine if luteolin helps improve symptoms of schizophrenia.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/08/2024
Locations: Maryland Psychiatric Research Center, Baltimore, Maryland
Conditions: Schizophrenia, Schizoaffective Disorder
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The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry
NCT02346435
Recruiting
Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, \<=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/08/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Kidney Neoplasm
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Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention
NCT06143852
Recruiting
The investigators will be randomizing 150 college student participants with high levels of social media use into either a 1) control condition (no intervention), a 2) mindfulness meditation cognitive intervention, or 3) a social media reduction + exercise replacement intervention. Participants complete intervention activities daily for one week. The investigators will collect self-report and behavioral measures of social media use and related psychological constructs at three time points: baseli... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/04/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Social Media Addiction, Depression, Anxiety, Well-Being, Psychological
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Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
NCT03891160
Recruiting
The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to study the correlation of having a 3D printed model with improvement in patient outcomes and compare those with patients who have had a VAD placement without a 3D model.
Gender:
ALL
Ages:
All
Trial Updated:
07/03/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Congenital Heart Disease
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Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
NCT03391778
Recruiting
This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.
Gender:
ALL
Ages:
All
Trial Updated:
07/02/2024
Locations: ADP Investigational Site, Baltimore, Maryland
Conditions: Neoplasms
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Robot Aided Rehabilitation - Intervention
NCT02359253
Recruiting
Sensorimotor impairments following stroke often involve complex pathological changes across multiple joints and multiple degrees of freedom of the arm and hand, thereby rendering them difficult to diagnose and treat. The objective of this study is to evaluate multi-joint neuromechanical impairments in the arm and hand, then conduct impairment-specific treatment, and determine the effects of arm versus hand training and the effects of passive stretching before active movement training.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/02/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Stroke
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Robot Aided Rehabilitation - Multi-joint Evaluations
NCT02359812
Recruiting
Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and proprioceptive acuity will be present among multiple degree of freedom in the upper limb. The stiffness and spasticity will increase with time post-stroke. The objective of this study is to quantify the progression throughout the arm and hand during recovery from stroke. The inves... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/02/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Stroke
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Investigation on the Cortical Communication (CortiCom) System
NCT03567213
Recruiting
The CortiCom system consists of 510(k)-cleared components: platinum PMT subdural cortical electrode grids, a Blackrock Microsystems patient pedestal, and an external NeuroPort Neural Signal Processor. Up to two grids will be implanted in the brain, for a total channel count of up to 128 channels, for six months. In each participant, the grid(s) will be implanted over areas of cortex that encode speech and upper extremity movement.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
07/01/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Tetraplegia, Locked-in Syndrome, Brainstem Stroke, Amyotrophic Lateral Sclerosis
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Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)
NCT03624374
Recruiting
In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.
Gender:
ALL
Ages:
All
Trial Updated:
07/01/2024
Locations: Hugo Moser Center for Leukodystrophies, Baltimore, Maryland
Conditions: Leukoencephalopathies, LBSL, Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation, White Matter Disease, Ataxia, Cerebellar, Genetic Disease
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Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
NCT05176808
Recruiting
The primary objective of this research study is to improve outcomes involving core social-communication symptoms for young children with ASD by increasing access to clinically validated early behavioral intervention through a telehealth parent coaching model. The investigators will test the hypothesis that telehealth-delivered Naturalistic Developmental Behavioral Intervention parent coaching (TC) is non-inferior to in-person coaching (IPC) for the treatment of core social-communication symptoms... Read More
Gender:
ALL
Ages:
Between 18 months and 33 months
Trial Updated:
07/01/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Autism Spectrum Disorder
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Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer
NCT05312671
Recruiting
This is a single arm, Phase II trial involving the use of atezolizumab plus platinum and etoposide for patients with locally advanced urothelial cancer. The primary goal of this trial is to assess the pathologic complete response rate at cystectomy in patients after being treated with a combination therapy of atezolizumab, platinum, and etoposide.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2024
Locations: Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer, Urothelial Carcinoma Bladder
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Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
NCT02201992
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland +7 locations
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
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