There are currently 1572 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Prophylactic Peptide Vaccine in Advanced ALK+ NSCLC
Recruiting
The purpose of this study is to evaluate the safety of a cancer peptide vaccine to prevent or delay acquired resistance in advanced ALK+ lung cancer patients currently on ALK targeted therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: NSCLC Stage IV, ALK Fusion Protein Expression
Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients
Recruiting
This study is being performed to see if 18F-FDS is a useful imaging agent for diagnosis of bacterial infections. Position Emission Tomography (PET)/ computed tomography (CT) scans will be obtained after intravenous injection of 18F-FDS to determine biodistribution and pathophysiology in diseased subjects.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/20/2024
Locations: Johns Hopkins Medical Institutions, Baltimore, Maryland
Conditions: Enterobacterial Infections, Oncologic Disease, Inflammatory Disease, Invasive Fungal Infections
Vaginal Cuff Brachytherapy Fractionation Study
Recruiting
The purpose of this study is to see the effects of two different standard of care treatments of endometrial cancer on sexual dysfunction. This study will compare two standard of care treatments: HDR (high dose radiation) vaginal brachytherapy 3 fractions of 7 Gy to HDR vaginal brachytherapy 6 fractions of 4Gy for early stage endometrial cancer.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: University of Maryland Medical Center (UMMC), Baltimore, Maryland
Conditions: Endometrial Cancer
Retraining Reaching in Cerebellar Ataxia
Recruiting
The purpose of this study is to test for benefits of reinforcement based training paradigm versus standard practice over weeks for improving reaching movements in people with ataxia.
Gender:
All
Ages:
Between 22 years and 80 years
Trial Updated:
05/17/2024
Locations: Motion Analysis Lab in the Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Cerebellar Ataxia
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
Recruiting
HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable the development of novel treatments for HD. The secondary objective is to generate a high quality plasma sample collection matching the CSF collections, which will also be used to evaluate biomarkers and pathways of relevance to HD research and development.
Gender:
All
Ages:
Between 11 years and 75 years
Trial Updated:
05/17/2024
Locations: John Hopkins University, Baltimore, Maryland
Conditions: Huntington's Disease
Systems Science Approaches to Improve Access to Healthier Foods: The FRESH Trial
Recruiting
Working with independently owned restaurants, a common source of calorie-rich, nutrient-poor foods in predominantly minority, low-income urban neighborhoods, has the potential to improve dietary quality, and contribute to cancer prevention. This study uses systems science approaches to improve access to healthier foods in independently owned restaurants by: 1) testing the effects of a novel intervention called FRESH (Focus on Restaurant Engagement to Strengthen Health) on dietary quality, health... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/16/2024
Locations: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
Conditions: Healthy Eating Index
The Impact of COVID-19 on Maternal and Neonatal Outcomes
Recruiting
The novel coronavirus (SARS-CoV-2) infection (COVID-19) has caused a worldwide pandemic. There is still much that is unknown regarding the virus, especially its effects on pregnancy, the fetus, and the neonate. This study seeks to evaluate adverse pregnancy and neonatal outcomes related to COVID-19 infection. The FDA has authorized emergency use authorization for the SARS-CoV-2 messenger ribonucleic acid (mRNA) vaccines from Pfizer and Moderna. Pregnant women were excluded from the Phase III cl... Read More
Gender:
Female
Ages:
Between 14 years and 55 years
Trial Updated:
05/16/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: COVID-19, Pregnancy; Infection
Recovery After Cerebral Hemorrhage
Recruiting
Background: While the intensive care of patients with life-threatening brain illnesses has advanced tremendously, a large number of therapies are still without proper scientific support. This can be partly explained by the fact that mechanisms of initial brain injury are still not well understood. Why additional neurological injury occurs during a patient's stay in the NeuroCritical Care Unit (NCCU) despite current best, evidence-based clinical practices, is also not well understood. However,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Intra Cerebral Hemorrhage, Subarachnoid Hemorrhage, Intraventricular Hemorrhage, Nontraumatic Haemorrhage
Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD
Recruiting
The investigators' goal is to develop neuroimaging biomarkers to predict response to treatment with methylphenidate, which then can be used in the development of novel pharmacological treatments for attention-deficit/hyperactivity disorder (ADHD). The overall objective of this study is to measure the changes in task-related neural activity related to symptoms of ADHD (measured by functional MRI) and brain glutamate levels (measured by magnetic resonance spectroscopy, MRS) after treatment with me... Read More
Gender:
All
Ages:
Between 6 years and 40 years
Trial Updated:
05/15/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: ADHD - Combined Type
Cerebellar Involvement in Alcohol Use Disorder (AUD)
Recruiting
The goal of this observational and interventional study is to better understand the involvement of the cerebellum in the brain reward system in persons with alcohol use disorder (AUD). The main questions it aims to answer are: What is the nature of cerebellar input to the ventral tegmental area (VTA) in the brain reward system, and how is it perturbed in AUD? What is the relationship between measures of cerebellar integrity and magnitude of reward activation to alcohol-related cues in cerebella... Read More
Gender:
All
Ages:
Between 25 years and 55 years
Trial Updated:
05/15/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Alcohol Use Disorder
Evaluating Emetine for Viral Outbreaks (EVOLVE)
Recruiting
The goal of this clinical trial (phase 2/phase 3) is to evaluate the efficacy and safety of emetine administered orally for symptomatic Covid-19 patients in patients ages 30 years and above. Participants will be asked to: Take Emetine 6mg orally for 10 consecutive days Be monitored by healthcare staff or self-monitor for daily vital signs and symptoms Undergo blood draws Researchers will compare the control group given placebo medicine to assess if emetine improved the symptoms of Covid-19.
Gender:
All
Ages:
30 years and above
Trial Updated:
05/15/2024
Locations: Johns Hopkins University, Division of Infectious Diseases, Baltimore, Maryland
Conditions: COVID-19
Heart Attack Research Program- Imaging Study
Recruiting
The HARP study is a multi-center, diagnostic observational study employing standardized imaging protocols in patients with MINOCA (MI with Non Obstructive Coronary Arteries) to determine the underlying diagnosis in each participant. Participants will be followed for recurrent clinical events, every 6 months, for a maximum of 10 years.
Gender:
All
Ages:
Between 21 years and 99 years
Trial Updated:
05/14/2024
Locations: Johns Hopkins Medical Center, Baltimore, Maryland
Conditions: Myocardial Infarction