There are currently 1093 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
NCT05952557
Recruiting
This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurrence who completed definitive locoregional therapy (with or without chemotherapy). The planned duration of treatment in either arm within the study will be 7 years.
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
06/18/2025
Locations: Research Site, Rochester, Minnesota
Conditions: Breast Cancer, Early Breast Cancer
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Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial
NCT06887829
Recruiting
The primary aim of this study is to investigate whether low-dose radiotherapy is an effective treatment to reduce the pain of knee osteoarthritis. A secondary aim is to determine whether patients experience any more measurable side effects than those receiving sham treatments.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
06/18/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Osteoarthritis, Knee
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ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk
NCT05064553
Recruiting
The primary objective is to assess overall sensitivity and specificity of Oncoguard™ Liver for hepatocellular cancer (HCC) detection in a surveillance population.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis, Liver Cancer
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The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
NCT05427370
Recruiting
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled in approximately 45 centers comparing revascularization by percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) in patients with multivessel/left main (LM) coronary artery disease (CAD) and reduced left ventricular ejection fraction (LVEF). The primary objective is to determine whether C... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Coronary Artery Disease, Heart Failure Systolic
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Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy
NCT06138873
Recruiting
Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality have been used. The Ablation Index (AI) is a variable incorporating power delivery in its formula and combining it with CF and time in a weighted equation which aims at allowing for a more precise esti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Ventricular Tachycardia, Ischemic Cardiomyopathy
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Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder (US UCB)
NCT07029256
Recruiting
This study is being done to test the feasibility and accuracy of using an ultrasound-guided core needle biopsy technique as a potential tool for staging urothelial carcinoma of the bladder (UCB).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Bladder Urothelial Carcinoma
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Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
NCT03892980
Recruiting
This study evaluates the safety and effectiveness of the da Vinci Surgical Systems in prophylactic Nipple Sparing Mastectomy procedures.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/16/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Nipple Sparing Mastectomy
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64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
NCT04868604
Recruiting
The aim of this study is to determine the safety and efficacy of 67Cu-SAR-bisPSMA in participants with PSMA-expressing metastatic castrate resistant prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Prostatic Neoplasms, Castration-Resistant
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Fecal Microbiota Transplantation for IBS
NCT05776914
Recruiting
The purpose of this study is to learn the efficacy and safety of fecal microbiota transplantation (FMT) using stool from a donor with low proteolytic activity and containing the bacteria Alistipes putredinis in patients with irritable bowel syndrome (IBS) and high proteolytic activity. Proteolytic activity is the breakdown of proteins into smaller polypeptides or amino acids.
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
06/16/2025
Locations: Mayo Clinic in Minnesota, Rochester, Minnesota
Conditions: Irritable Bowel Syndrome, Diarrhea
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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT06297226
Recruiting
The purpose of this study is to evaluate the effectiveness and safety of Arlocabtagene Autoleucel (BMS-986393) in participants with relapsed or refractory multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota
Conditions: Multiple Myeloma
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Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial
NCT06378866
Recruiting
This phase II trial studies the effects of stereotactic body radiation therapy (SBRT) and the timing of treatment with androgen receptor pathway inhibitor (ARPI) plus androgen deprivation therapy (ADT) in treating patients with hormone sensitive prostate cancer that has spread from where it first started to other places in the body (metastatic), and that has come back after a period of improvement (recurrent). SBRT is a type of external radiation therapy that uses special equipment to position a... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Recurrent Castration-Sensitive Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8, Recurrent Prostate Cancer, Castration-resistant Prostate Cancer
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NAL ER IPF Respiratory Function and Safety Study
NCT07036029
Recruiting
The primary purpose of this study is to assess the safety and tolerability of escalating doses of NAL ER and to evaluate its effect on respiratory function in participants with IPF.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Idiopathic Pulmonary Fibrosis
Register for Updates