There are currently 1102 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Retrospective Non-interventional Study of Stiripentol Use in Dravet Patients in the USA
NCT05544058
Recruiting
The present study aims to collect data regarding the history of the disease, previous and current treatments, and the clinical status of Dravet patients during the 3 months prior to stiripentol initiation, the first 3 months on stiripentol and the last 3 months on stiripentol (irrespective of stiripentol discontinuation).
Gender:
All
Ages:
All
Trial Updated:
09/20/2022
Locations: Mayo clinic, Rochester, Minnesota
Conditions: Dravet Syndrome
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MR-Guided Focused Ultrasound in the Treatment of Focal Epilepsy (EP001)
NCT02804230
Recruiting
The purpose of this study is to evaluate the feasibility, safety, and initial effectiveness of Exablate thermal ablation of a focal epileptic target area in the brain of patients suffering from medication-refractory epilepsy, using the Exablate transcranial system to produce multiple sonications targeted in the focus of interest. The investigators will establish the feasibility and collect data to establish the basic safety of this type of treatment as the basis for later studies that will evalu... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/07/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Epilepsy
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Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
NCT03716531
Recruiting
This research study is studying an intervention as a possible treatment for pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Mayo Clinic, Rochester, Rochester, Minnesota
Conditions: Pancreas Cancer
Register for Updates
CODY: A Study Evaluating The Safety And Efficacy Of QTORIN 3.9% Sirolimus Topical Gel For The Prevention Of Basal Cell Carcinomas (BCCs) In Patients With Gorlin Syndrome
NCT04893486
Recruiting
A Phase 2b study looks at the safety and efficacy of a treatment that is being investigated for people with certain diseases. This study will be conducted at multiple centers in the United States where participants with Gorlin Syndrome, also known as basal cell nevus syndrome, will be randomly placed into two groups; one group will receive the active topical gel, the other a topical vehicle gel, also know as placebo. Participants will apply this topical product to their face once a day for 6 mon... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/26/2022
Locations: Mayo Clinic - Minnesota, Rochester, Minnesota
Conditions: BCCs in Gorlin Syndrome Patients
Register for Updates
Endorotor Resection In Refractory Barrett's Dysplasia Patients
NCT03364114
Recruiting
The aim of the clinical trial is to evaluate the EndoRotor®'s ability to completely remove areas of Barrett's esophagus considered refractory after 3 failed ablation treatments (Radiofrequency Ablation (RFA) and/or Cryotherapy) or in patients with at least 1 failed ablative procedure (RFA and/or Cryotherapy) and are intolerant to the procedure due to pain, where intolerant is defined as post-dysphagia or odynophagia persisting for 24 hours or greater or requiring narcotic analgesia for a duratio... Read More
Gender:
All
Ages:
Between 30 years and 89 years
Trial Updated:
08/01/2022
Locations: The Mayo Clinic, Rochester, Minnesota
Conditions: Barrett's Esophagus With Dysplasia
Register for Updates
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
All
Ages:
All
Trial Updated:
07/28/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
Register for Updates
Artisan Aphakia Lens for the Correction of Aphakia in Children
NCT01547442
Recruiting
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
06/24/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Aphakia
Register for Updates
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia
NCT05111288
Recruiting
This study is being done to observe the effects of treatment from a device called the Bioboosti which utilizes pulsed electromagnetic waves on its ability to improve blood flow to the heart tissue in individuals with coronary artery disease (CAD).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2022
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Coronary Artery Disease, Myocardial Infarction
Register for Updates
Struvite Stones Antibiotic Study
NCT02375295
Recruiting
The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).
Gender:
All
Ages:
19 years and above
Trial Updated:
05/16/2022
Locations: Mayo Clinic - Rochester, MN, Rochester, Minnesota
Conditions: Kidney Stones
Register for Updates
Prostate Imaging Using MRI +/- Contrast Enhancement
NCT04571840
Recruiting
This prospective clinical trial (PRostate Imaging using Mri +/- contrast Enhancement (PRIME)) aims to assess whether biparametric MRI (bpMRI) is non-inferior to multiparametric mpMRI (mpMRI) in the detection of clinically significant prostate cancer. This means that we are comparing MRI scans that requires injection of IV contrast (the current standard practice) versus MRI scans that can be performed without IV contrast in the detection of prostate cancer.
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/11/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Prostate Cancer
Register for Updates
Study of ISB 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma
NCT03309111
Recruiting
The purpose of this study is to assess safety, efficacy, pharmacokinetic (PK)/pharmacodynamic (PD), and immunogenicity with ISB 1342 in subjects with relapsed/refractory multiple myeloma.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2022
Locations: Mayo Clinic Cancer Center (MCCC) - Rochester, Rochester, Minnesota
Conditions: Relapsed/Refractory Multiple Myeloma
Register for Updates
Genetics of QT Prolongation With Antiarrhythmics
NCT02439658
Recruiting
To assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being loaded with dofetilide or sotalol.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Long QT Syndrome, Drug Toxicity
Register for Updates