There are currently 1093 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures
NCT05806996
Recruiting
This research is being done to find out whether intravenous magnesium is effective in the treatment of bladder spasms after urologic surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Mayo Clinic in Minnesota, Rochester, Minnesota
Conditions: Bladder Spasms
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Accelerated Resolution Therapy for Early Maladaptive Grief
NCT05624879
Recruiting
The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregivers (FCGs). Additionally, to better understand predictors of response to ART, and cognitive processes that occur among grieving individuals following ART.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/08/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Grief
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Evaluation of Plasma Renin Concentrations in Cardiac Surgery
NCT06895213
Recruiting
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cardiac Surgery with Cardiopulmonary Bypass
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The Effect of Synaquell™ in Contact Sport Athletes
NCT06104670
Recruiting
This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth contact sport athletes.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
05/07/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
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Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients
NCT05587751
Recruiting
The purpose of this research study is to evaluate whether undergoing gender affirming care will impact the way the lungs function.
Gender:
ALL
Ages:
14 years and above
Trial Updated:
05/06/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Hormonal Gender-Affirming Therapy
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Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
NCT06333652
Recruiting
The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
05/06/2025
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Preeclampsia
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A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening
NCT06891222
Recruiting
The purpose of this study is to evaluate and compare the effectiveness of active screening for SHD in asymptomatic outpatients referred for an ECG, using a combination of AI-ECG and FOCUS. Invites will be sent and participants enrolled electronically.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cardiac Disease
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Wound Closure Techniques in Primary Spine Surgery
NCT04396613
Recruiting
The Researchers are trying to determine if there is a difference in blood flow around a wound site when comparing three different types of wound closure techniques.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Injuries
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HEAL-IST IDE Trial
NCT05280093
Recruiting
Inappropriate Sinus Tachycardia (IST) is a prevalent and debilitating condition in otherwise healthy younger patients, resulting in significant loss of quality of life, lacking effective treatment options or systematic clinical evidence to support a therapy. The primary objective of this clinical trial is to evaluate the safety and effectiveness of a hybrid sinus node sparing ablation procedure for the treatment of symptomatic drug refractory or drug intolerant IST.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/05/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Inappropriate Sinus Tachycardia
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A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
NCT05600426
Recruiting
Severe Aplastic Anemia (SAA) is a rare condition in which the body stops producing enough new blood cells. SAA can be cured with immune suppressive therapy or a bone marrow transplant. Regular treatment for patients with aplastic anemia who have a matched sibling (brother or sister), or family donor is a bone marrow transplant. Patients without a matched family donor normally are treated with immune suppressive therapy (IST). Match unrelated donor (URD) bone marrow transplant (BMT) is used as a... Read More
Gender:
ALL
Ages:
Between 0 years and 25 years
Trial Updated:
05/05/2025
Locations: Mayo Clinic Rochestser, Rochester, Minnesota
Conditions: Severe Aplastic Anemia
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Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06029972
Recruiting
The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treated with tilpisertib fosmecarbil with participants treated with placebo. The primary objective of this study is to demonstrate the efficacy of tilpisertib fosmecarbil, compared to placebo control, in achieving Clinical Response at Week 12.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/05/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Ulcerative Colitis
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A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
NCT03661866
Recruiting
TARGET-DERM is a longitudinal, observational study of adult and pediatric patients being managed for Atopic Dermatitis and other Immune-Mediated Inflammatory Skin Conditions (IMISC) in usual clinical practice. TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety and effectiveness of current and future therapies.
Gender:
ALL
Ages:
All
Trial Updated:
05/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Atopic Dermatitis, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Alopecia Areata, Chronic Spontaneous Urticaria
Register for Updates