There are currently 1093 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Remote Monitoring with Health-Coaching to Improve Quality of Life in Older Patients with Multiple Myeloma
NCT06145581
Recruiting
This clinical trial tests the effectiveness of a home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching to decrease fatigue and improve quality of life in older patients with multiple myeloma (MM). Studies have shown that MM patients have the highest symptom burden among all blood cancers, with older patients experiencing more symptoms and problems, such as fatigue and decreased quality of life, compared to younger patient... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
03/24/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Multiple Myeloma
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Short Course Radiotherapy for the Treatment of Patients with Glioblastoma, SAGA Study
NCT05781321
Recruiting
This phase II trial compares the effect of short course radiotherapy (RT) to standard course RT for the treatment of patients diagnosed with glioblastoma (GBM). The researchers want to learn whether the shorter course treatment is non-inferior (not worse than the standard of care), for patients with GBM. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Short course radiotherapy delivers higher doses of radiation over a shorter per... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/23/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Glioblastoma
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Efficacy of Nerve Blocks for Episodic Migraine
NCT05734625
Recruiting
The purpose of this study is to see how well blocking two to ten of the scalp nerves (that give feeling to the scalp and are painful during migraine headaches) with bupivacaine anesthetic (numbing medication) and low dose methylprednisolone (cortisone-like medicine or steroid) work for treating and preventing migraines. Our hypothesis is that the pain of most episodic migraine headaches can be eliminated and prevented for months by blocking the nerves that give pain sensation during a migraine.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Episodic Migraine
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Circadian Rhythms in Human Adipose
NCT06891534
Recruiting
The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Obesity, Abdominal, Feeding Patterns
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Acute Recording of Stereotyped High-Frequency Oscillations
NCT05439655
Recruiting
Overall, this study will investigate the functional utility of stereotyped HFOs by capturing them with a new implantable system (Brain Interchange - BIC of CorTec), which can sample neural data at higher rates \>=1kHz and deliver targeted electrical stimulation to achieve seizure control. In contrast to current closed-loop systems (RNS), which wait for the seizure to start before delivering stimulation, the BIC system will monitor the spatial topography and rate of stereotyped HFOs and deliver t... Read More
Gender:
ALL
Ages:
Between 3 years and 70 years
Trial Updated:
03/20/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Epilepsy
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Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
NCT06886087
Recruiting
The goal of this observational study is to learn if PRAT thickness is a marker of visceral obesity and its influence on donors' kidney function and blood pressure in living kidney donors. Population includes male/female, 18 years and up, living kidney donors scheduled for nephrectomy within 6 months, with a BMI of ≤ 27 or \>30, with a PRAT thickness measurement of ≥ 14mm or ≤10mm on CT. The main area it aims to help in, is future care managing blood pressure and obesity in living kidney transpla... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/20/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Living Kidney Donation, Hypertension, Nephrectomy
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R-3750 in Patients with Mild to Moderate Ulcerative Colitis
NCT05666960
Recruiting
The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-3750) in patients with mild to moderate ulcerative colitis. Patients will take an oral dosage of probiotic (R-3750) and provide patient-reported and physician scored measures of their colitis. Blood and fecal evaluations of inflammation and assessment of probiotic (R-3750) on fecal levels will also be measured.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/19/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Ulcerative Colitis Chronic Mild, Ulcerative Colitis Chronic Moderate, Ulcerative Colitis Chronic, Ulcerative Colitis
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INTERogating Cancer for Etiology, Prevention and Therapy Navigation
NCT06008392
Recruiting
This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells and normal cells in the body. Researchers may request to access these data as they explore how to better prevent, screen, or treat cancer. This study is also being done to create a biobank (library) of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cancer, Cancer Gene Mutation, PAN Gene Mutation, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
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R-5280 in Newly Diagnosed Patients with Type 1 Diabetes
NCT06057454
Recruiting
Evaluating the adverse events and tolerance of R-5280 in Mitigating Type 1 Diabetes in Newly Diagnosed Patients
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
03/19/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Type 1 Diabetes, Type 1 Diabetes (Juvenile Onset), Diabetes Mellitus, Type 1
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Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial
NCT06080698
Recruiting
The Gram-negative bloodstream infection Oral Antibiotic Therapy trial (The GOAT Trial) is a multi-center, randomized clinical trial that hypothesizes that early transition to oral antibiotic therapy for the treatment of Gram-Negative BloodStream Infection (GN-BSI) is as effective but safer than remaining on intravenous (IV) antibiotic therapy for the duration of treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Gram-negative Bacteremia
Register for Updates
VTP-1000 in Adults with Celiac Disease
NCT06310291
Recruiting
GLU001 is a first-in-human clinical trial to assess the safety and tolerability of VTP-1000 for adults with celiac disease. This trial will assess VTP-1000 at various dose levels compared to placebo in a single ascending dose (SAD) and multiple ascending dose (MAD) format. Participants will be followed for a short period of time to assess the impact of VTP-1000 on their immune system (Adverse events, reactions in the blood, and physical exam differences). Participants enrolled in the MAD portion... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Celiac Disease
Register for Updates
Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy
NCT06891209
Recruiting
This study explores and compares health-related quality of life and urinary outcomes in postoperative partial cystectomy and matched radical cystectomy patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Bladder Carcinoma
Register for Updates