There are currently 1093 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Pulmonary Hypertension in Left Heart Disease
NCT05935605
Recruiting
The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expired gas metabolic testing and blood sampling.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pulmonary Hypertension, Pulmonary Vascular Disease, Left Heart Disease
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A Study of High-intensity Strength Training and Thoracic Aorta Dilatation
NCT06684496
Recruiting
The purpose of this study is to describe the prevalence of thoracic aorta dilatation among a group of older (age \> 35 years), experienced weightlifters (\>5 years of weightlifting experience). The secondary aim of this study is to report the prevalence of thoracic aorta dilatation among 3 different groups of weightlifters (body builders, cross-fit athletes, and power lifters).
Gender:
ALL
Ages:
35 years and above
Trial Updated:
02/17/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Thoracic Aorta Dilatation
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Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
NCT02923011
Recruiting
Osteoid osteomas are painful, benign bone tumors that occur most frequently in young males between ages 10 and 20 years. The goal of the proposed study is based on the premise that MRgFUS is noninferior to CT-guided radiofrequency ablation (CTgRFA), in terms of pain reduction following treatment of osteoid osteomas, and offers possible improvements with regards to 1) post-procedural pain, 2) clinical resource utilization, 3) patient experience, and/or 4) adverse events. The data from the current... Read More
Gender:
ALL
Ages:
8 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Osteoid Osteoma
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Gynecologic Extramammary Paget's Disease
NCT03564483
Recruiting
In addition to evaluating treatment outcomes, tissue samples and swabs will be collected as part of this study to allow physicians to better understand Extramammary Paget's Disease (EMPD). The researchers also want to learn more about the microorganisms (microbiome) that live on or near the areas of skin affected by EMPD, in order to better understand this condition.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Extramammary Paget's Disease, Extramammary Paget Disease, Paget Disease, Extramammary, Extramammary Paget's Disease of Vulva (Diagnosis), Extramammary Paget's Disease of Vagina (Diagnosis), Extramammary Paget's Disease Vulva Invasive, Extramammary Paget's Disease of Anus (Diagnosis), Extramammary Paget's Disease of Anal Canal (Diagnosis), Extramammary Paget's Disease of Skin
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Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
NCT04411823
Recruiting
Researchers are trying to identify predictors for gastroesophageal reflux disease after sleeve gastrectomy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Gastroesophageal Reflux, Sleeve Gastrectomy, Bariatric Surgery Complication
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Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study
NCT05075980
Recruiting
This clinical trial studies how well intensity modulated proton therapy (IMPT) or intensity modulated X-ray (radiation) therapy (IMRT) works after surgery in treating patients with head and neck cancer. IMPT is a type of radiation therapy that allows for the most accurate application of proton radiation to the tumor and has the potential to reduce treatment-related side effects. IMRT is a type of 3-dimensional radiation therapy that uses computer-generated images to show the size and shape of th... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Head and Neck Carcinoma, Head and Neck Carcinoma of Unknown Primary, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Metastatic Malignant Neoplasm in the Lymph Nodes, Nasal Cavity Carcinoma, Oral Cavity Carcinoma, Oropharyngeal Carcinoma, Paranasal Sinus Carcinoma, Salivary Gland Carcinoma, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck
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Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer
NCT06325046
Recruiting
This clinical trial evaluates changes in quality of life after two treatments with near margin-less adaptive radiation therapy (ART) compared to five treatments with standard stereotactic ablative body radiotherapy (SABR) in patients with prostate cancer that has not spread to other parts of the body (localized). ART is a type of radiation therapy that uses information gathered during the treatment cycle to inform, guide, and alter future radiation treatments with respect to location and dose. I... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
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Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
NCT06306963
Recruiting
The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible bleeding. It can also cause symptoms such as abdominal pain and nausea. By participating in this study, you will help us learn how often these symptoms occur and how they relate to stomach functioning.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
02/13/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Gastric Antral Vascular Ectasia, Cirrhosis, Chronic Kidney Disease
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Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms
NCT05549661
Recruiting
This phase I trial evaluates the safety, effectiveness, and best dose of onvansertib for the treatment of patients with chronic myelomonocytic leukemia and Myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) overlap neoplasms that has come back (recurrent) or that does not respond to treatment (refractory). Onvansertib is a drug that binds to and inhibits an enzyme called PLK1, preventing cancer cell proliferation and causing cell death.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Recurrent Chronic Myelomonocytic Leukemia, Refractory Chronic Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified, Recurrent Atypical Chronic Myeloid Leukemia, Recurrent Myelodysplastic/Myeloproliferative Neoplasm, Refractory Myelodysplastic/Myeloproliferative Neoplasm
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Vitamin D Sulfates in Breastmilk
NCT06203041
Recruiting
Infants The purpose of this study is to measure breastmilk's vitamin D sulfate nutritional value in infant's saliva and digesta (gut). Breastfeeding Mothers The purpose of this study is to measure Vitamin D sulfates in freshly expressed breastmilk samples before and after 28 days of Vitamin D supplementation in lactating mothers.
Gender:
ALL
Ages:
Between 1 month and 60 years
Trial Updated:
02/12/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Vitamin D Deficiency, Breast Milk Collection
Register for Updates
Biobank for Cholestatic Liver Diseases.
NCT03445585
Recruiting
This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC).
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/10/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis, Cholangiocarcinoma, Liver Cancer
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Abatacept for the Treatment of Giant Cell Arteritis
NCT04474847
Recruiting
This randomized, double-blind, placebo-controlled trial will seek to determine the efficacy of abatacept in GCA. To examine this objective, 62 eligible patients who have newly diagnosed or relapsing GCA within 8 weeks prior to screening will be randomized at a 1:1 ratio to receive subcutaneous abatacept 125mg/week or placebo. Patients who achieve remission will remain on their blinded assignment for 12 months at which time abatacept/placebo will be stopped. Patients who do not achieve remission... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
02/10/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Giant Cell Arteritis
Register for Updates