There are currently 1094 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Quality of Life Assessment Between Internal Endoscopic Versus Percutaneous Drainage in Biliary Obstruction
NCT04857424
Recruiting
The aim of this study is to compare the quality of life in subjects with benign and malignant biliary obstruction who have or will undergo endoscopic retrograde cholangiopancreatography (ERCP) and/or percutaneous trans-hepatic biliary drainage (PTBD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/03/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Biliary Obstruction
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Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
NCT05538247
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
NCT06030063
Recruiting
The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who receive general anesthesia for cesarean delivery.
Gender:
FEMALE
Ages:
Between 15 years and 55 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cesarean Delivery, General Anesthesia
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Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study
NCT05077735
Recruiting
This phase II trial studies the clinical outcomes of hypofractionated radiation therapy in patients with diffuse midline gliomas. This study aims to change the way radiation is delivered, from giving 6 weeks of radiation all at once to giving 2 weeks of radiation. This may determine if there is a difference in the outcome of the treatment, and most importantly, the patients' quality of life.
Gender:
ALL
Ages:
1 year and above
Trial Updated:
12/31/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant
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Thoracic Specimen Registry
NCT04118660
Recruiting
The purpose of the registry will be to support ongoing research in the etiology, early diagnosis, clinical management, and prognosis of lung cancer and other cancers and diseases of the thorax by developing a complete repository of specimens from patients with thoracic disease including but not limited to suspected lung cancer, mediastinal and pleural tumors, lung transplants and from patients at a very high risk of developing other thoracic cancers or other thoracic diseases.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Thoracic Diseases, Lung Cancer, Lung Transplant
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A Study of Sex Differences in Neurocirculatory Control
NCT06261034
Recruiting
The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).
Gender:
ALL
Ages:
Between 20 years and 70 years
Trial Updated:
12/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Obstructive Sleep Apnea
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AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction
NCT06580158
Recruiting
Two recently developed artificial intelligence-enabled electrocardiogram (AI-ECG) models have been developed to detect aortic stenosis (AS) and diastolic dysfunction (DD). AI-ECG for AS has a sensitivity of 78% and specificity of 74%, and AI-ECG for DD has a sensitivity of 83% and specificity of 80%. However, these models have never been prospectively applied to diagnose AS or DD, which may be useful for patients and providers from a diagnostic and prognostic perspective and especially in settin... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
12/30/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Aortic Stenosis, Diastolic Dysfunction
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Understanding of Genetics by Men At Risk for Prostate Cancer
NCT04550845
Recruiting
With this greater certainty regarding prognosis, men with localized prostate cancer are now equipped with make better treatment planning decisions. This study is designed to investigate the understanding of prognostic genetic technology in African American and rural White men at risk for localized prostate cancer.
Gender:
MALE
Ages:
Between 40 years and 95 years
Trial Updated:
12/24/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Prostate Cancer
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A Prospective Observational Study of Foam Sclerotherapy .
NCT04111692
Recruiting
An observational prospective study to determine the impact of foam sclerotherapy of large, dominant kidney/liver cysts on quality of life outcomes and kidney/liver cyst volumes at up to 12 months of follow-up in patients with autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
12/23/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Autosomal Dominant Polycystic Kidney, Renal Cyst, Autosomal Dominant Polycystic Liver Disease, Hepatic Cyst
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CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations
NCT05689021
Recruiting
This phase II trial tests how well abiraterone acetate/niraparib (CJNJ-67652000 \[niraparib/abiraterone acetate fixed-dose combination\]) and prednisone works in treating patients with castration-resistant prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic) and who have a mutation in the SPOP gene. CJNJ-67652000 (niraparib/abiraterone acetate fixed-dose combination) is a drug which stops certain cancer cells from being able to repai... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
12/23/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
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Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis
NCT04858009
Recruiting
This phase II trial studies the effects of hyperthermic intraperitoneal chemotherapy (HIPEC) in treating patients with pancreatic cancer that has spread to the internal abdominal area (peritoneal metastasis). Chemotherapy drugs, such as nab-paclitaxel and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. HIPEC involves "heated" chemotherapy that is placed directly in the abdomen th... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/20/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Metastatic Pancreatic Carcinoma, Stage IV Pancreatic Cancer AJCC v8, Metastatic Malignant Neoplasm in the Peritoneum
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VIDAS® TBI Real Life Performance in Subjects with Mild Traumatic Brain Injury (mTBI)
NCT06449183
Recruiting
Decision Rules for an initial CT-scan in patients arriving to Emergency Department (ED) and presenting a mild traumatic brain injury could be optimized by the use of an objective parameter easily and rapidly measured. This may be the place for serum biomarkers providing a quick and accurate assessment. BioMérieux has now developed an automated assay for the measurement of serum Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin C-terminal Hydrolase (UCH-L1), the VIDAS® TBI assay to fill out th... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Mild Traumatic Brain Injury
Register for Updates