There are currently 1091 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
ADSTILADRIN Early Utilization and Outcomes in the Real World Setting
NCT06026332
Recruiting
Multi-center, prospective non-interventional study to collect data on the early use of Adstiladrin in the US and Israel. Data will be collected from patients and prescribing physicians in a real-world setting
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Ferring Investigational Site, Rochester, Minnesota
Conditions: Bladder Cancer
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A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
NCT06644768
Recruiting
This study will compare Valemetostat Tosylate Plus Pembrolizumab vs Pembrolizumab Alone in First-line NSCLC Without Actionable Genomic Alterations
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Mayo Clinic - Rochester, Rochester, Minnesota
Conditions: Non-small Cell Lung Cancer, Lung Cancer
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NOX4 and Related Biomarkers in ADPKD
NCT04630613
Recruiting
To determine the value of NOX4, markers of mitochondria injury and function, and oxidative stress as real-time biomarkers to assess disease severity in patients with early autosomal dominant polycystic kidney disease (ADPKD).
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
11/08/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Autosomal Dominant Polycystic Kidney Disease
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Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation
NCT05371470
Recruiting
The purpose of this study is to learn if a voice analysis smartphone app which detects anxiety and depression could be used along with cardiac rehabilitation to improve results compared to cardiac rehabilitation alone.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Myocardial Infarction
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Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech
NCT01818661
Recruiting
The study is designed to determine the relationship between structural and functional changes in the brain on imaging and progression of speech and language, neurological and neuropsychological features in patients with neurodegenerative apraxia of speech (AOS).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: PPA, Non-fluent Aphasia, Apraxia of Speech, Primary Progressive Non-fluent Aphasia, Primary Progressive Aphasia
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A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy
NCT02605785
Recruiting
This study is designed to learn more about overall tau burden in the brain of patients with Progressive Supranuclear Palsy (PSP).
Gender:
ALL
Ages:
35 years and above
Trial Updated:
11/07/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Progressive Supranuclear Palsy
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Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
NCT04199000
Recruiting
The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.
Gender:
ALL
Ages:
All
Trial Updated:
11/07/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Congenital Disorders of Glycosylation
Register for Updates
Study of Tadalafil Vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology
NCT05206955
Recruiting
The purpose of this study is to find out more about the effectiveness of Tadalafil in improving hemodynamic capabilities, endothelial function, and end-organ function in patients who have previously undergone a Fontan Palliation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Fontan Palliation
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Evaluation of a Multilevel Intervention on Adult COVID-19 and Influenza Vaccination Rate
NCT06646406
Recruiting
The study will test two tactics to improve uptake of two vaccines in adults. The vaccines prevent COVID-19 and influenza. Both are common and harmful. Most adults do not get either vaccine. This is despite strong recommendations that all adults get both vaccines. The study will involve adult patients at eight Mayo Clinic primary care practices in Rochester and Kasson. The study will test the two tactics together. Four clinics will get the two tactics. The other four clinics will not. The study... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
11/07/2024
Locations: Mayo Clinic, Rochester, Minnesota +2 locations
Conditions: COVID-19 Immunisation, Influenza Vaccine
Register for Updates
Use of Midodrine in Septic Shock Patients
NCT06319248
Recruiting
This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications. Researchers want to see if Midodrine can help people with sepsis need fewer vasopressors, which could mean shorter hospital stays, less time with uncomfortable tubes, and a smoother recovery overall.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/05/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Sepsis, Low Blood Pressure
Register for Updates
North American Prodromal Synucleinopathy Consortium Stage 2
NCT05826457
Recruiting
This study will enroll participants with idiopathic REM sleep behavior disorder (RBD) and healthy controls for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: REM Sleep Behavior Disorder, Parkinson Disease, Lewy Body Dementia, Dementia With Lewy Bodies, Multiple System Atrophy, REM Sleep Parasomnias
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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
NCT05863195
Recruiting
This phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in addition to standard of care chemotherapy versus standard of care chemotherapy alone in treating patients with colorectal cancer that has spread to the liver (liver metastases) and cannot be removed by surgery (unresectable). HAI uses a catheter to carry a tumor-killing chemotherapy drug called floxuridine directly into the liver. HAI is already approved by the Food and Drug Administration (FDA) for use in metas... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver, Stage IV Colorectal Cancer AJCC v8, Unresectable Colorectal Carcinoma
Register for Updates