Nebraska is currently home to 712 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Omaha, Lincoln, Kearney and Grand Island. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Lu AF28996 in Participants With Parkinson's Disease (PD)
NCT04291859
Recruiting
The purpose of this study is to investigate the safety of Lu AF28996, how well it is tolerated and what the body does to the drug in participants with Parkinson's disease.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
05/07/2025
Locations: Neurology Consultants of Nebraska, Omaha, Nebraska
Conditions: Parkinson Disease
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Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
NCT04068597
Recruiting
A Phase 1/2a study to assess the safety, tolerability, PK and biological activity of CCS1477 (inobrodib) in patients with Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukaemia or High Risk Myelodysplastic syndrome.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2025
Locations: Nebraska Cancer Specialists, Omaha, Nebraska
Conditions: Haematological Malignancy, Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma, Higher-risk Myelodysplastic Syndrome, Peripheral T Cell Lymphoma
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MB-105 in Patients With CD5 Positive T-cell Lymphoma
NCT06534060
Recruiting
This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon two-stage optimal design.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: University of Nebraska, Omaha, Nebraska
Conditions: Lymphoma, T-Cell
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A Cross-sectional Partnership to Improve Prevention and Health Equity Among African Americans
NCT05903885
Recruiting
African Americans face racial disparities in colorectal cancer (CRC), with lower screening rates and higher incidence and mortality rates. To address this gap and improve CRC screening rates, investigators aims to recruit a total of 1,200 African American participants aged 45-75 during their visits to the DMV, 4606 N 56th St Ste100, Omaha, for CRC screening. All participants will receive a free Fecal Immunochemical Test (FIT) kit with a prepaid return envelope, a culturally tailored educational... Read More
Gender:
ALL
Ages:
Between 45 years and 75 years
Trial Updated:
05/06/2025
Locations: Department of Motor Vehicles (DMV), Omaha, Nebraska
Conditions: Colorectal Cancer, Prevention
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A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Participants
NCT05831111
Recruiting
The purpose of this study is to evaluate the safety and reactogenicity of mRNA-1195 in healthy participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
05/06/2025
Locations: Velocity Clinical Research, Grand Island, Nebraska
Conditions: Epstein-Barr Virus Infection
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Porcine Membrane vs Bovine Wound Dressing in Human Tooth Extraction Sites
NCT05802602
Recruiting
The purpose of this study is to compare porcine collagen membrane and bovine collagen wound dressing in human tooth extraction sites. The outcomes measured will be soft tissue thickness changes as well as bone density changes.
Gender:
ALL
Ages:
Between 19 years and 65 years
Trial Updated:
05/06/2025
Locations: University of Nebraska Medical Center, College of Dentistry, Lincoln, Nebraska
Conditions: Wound Heal
Register for Updates
The Short-term Verbal Memory Endophenotype for Developmental Language Disorder Language Disorder
NCT06968169
Recruiting
The goal of this clinical trial is to determine how memory and attention affect the ability of children with developmental language disorder (DLD) to learn and use new vocabulary.
Gender:
ALL
Ages:
Between 5 years and 10 years
Trial Updated:
05/05/2025
Locations: Boys Town National Research Hospital, Omaha, Nebraska
Conditions: Developmental Language Disorder, Healthy Subjects
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A Trial in Healthy Adult Participants to Evaluate the Safety, Tolerability, and Behavior in the Body of TBD11
NCT06707142
Recruiting
This is a randomized, double-blind, placebo controlled First in human (FIH) trial of TBD11, administered to healthy adults. The trial will be conducted in two parts. Part 1 will consist of single ascending dose (SAD) and Food effect (FE) cohorts, and Part 2 will consist of multiple ascending dose (MAD) cohorts.
Gender:
ALL
Ages:
Between 19 years and 55 years
Trial Updated:
05/05/2025
Locations: Celerion, Lincoln, Nebraska
Conditions: Healthy Adult Participants
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GEMINI-NSCLC: NSCLC Biomarker Study
NCT05236114
Recruiting
GEMINI NSCLC Study is a non-interventional study that will be collecting clinical and molecular health information from patients with NSCLC who will receive longitudinal blood collection in addition to their standard of care therapy and disease surveillance with the goals of identifying the molecular evolution of lung cancer with standard of care therapy, and determining the utility of ctDNA dynamics to predict risk of recurrence and therapeutic outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Nebraska Cancer Specialists, Omaha, Nebraska
Conditions: Non-Small Cell Lung Cancer
Register for Updates
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
NCT05234177
Recruiting
The study is an observational multicenter evaluation of participants with colorectal cancer (CRC) who will receive longitudinal plasma ctDNA biomarker profiling in addition to their standard-of-care therapy and disease surveillance.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Nebraska Cancer Specialists, Omaha, Nebraska
Conditions: Colorectal Cancer
Register for Updates
Chyme Reinfusion for Type 2 Intestinal Failure
NCT04577456
Recruiting
This project aims to introduce and evaluate a novel assistive prosthetic system that helps prevent and treat nutrient and fluid loss from enterocutaneous fistulas. The device system functions simply to return the output from a fistula back into the distal limb of the intestine.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
05/04/2025
Locations: University Nebraska, Lincoln, Nebraska
Conditions: Intestinal Failure, Enterocutaneous Fistula, Ileostomy - Stoma, High Output Stoma
Register for Updates
A First-in-human Research Study on How NNC0662-0419 Works in People Living With Overweight or Obesity
NCT06737536
Recruiting
This study is testing a new study medicine which may be used to treat people living with overweight or obesity. The purpose of the study is to see if the new study medicine is safe, how it works in human body and what human body does to the study medicine. Participants will either get the study medicine NNC0662-0419 or placebo (a "dummy" medicine without any active ingredients) given by study staff as an injection under participants skin. Which treatment participants will get is decided by chanc... Read More
Gender:
ALL
Ages:
Between 19 years and 55 years
Trial Updated:
05/02/2025
Locations: Celerion, Lincoln, Lincoln, Nebraska
Conditions: Overweight, Obesity
Register for Updates