New Hampshire is currently home to 346 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Lebanon, Manchester, Nashua and Portsmouth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Observational Pilot Study to Test a Smartwatch-based EMA Method During Exercise With Breast Cancer Survivors
NCT05868746
Recruiting
The goal of this pilot study is to evaluate the feasibility and acceptability of collecting ecological momentary assessment data regarding feeling states during physical activity among a cohort of breast cancer survivors, using a novel smartwatch app created by the study team called "PHITbit."
Gender:
All
Ages:
18 years and above
Trial Updated:
01/19/2024
Locations: Dartmouth-Hitchcock Clinic, Lebanon, New Hampshire
Conditions: Breast Cancer
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R-2487 in Patients With Rheumatoid Arthritis
NCT05961592
Recruiting
The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-2487) in patients with Rheumatoid Arthritis. Patients will take an oral dosage of probiotic (R-2487) and physicians will assess and measure their Rheumatoid Arthritis. Blood and fecal evaluations of inflammation and assessment of probiotic (R-2487) on fecal level will also be measured.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
01/18/2024
Locations: Dartmouth Hitchcock Medical Center (DHMC), Lebanon, New Hampshire
Conditions: Arthritis, Rheumatoid
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Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
NCT03728985
Recruiting
Prospective, non-randomized, , multicenter study with two independent arms: Primary Study Arm - TAAA and Pararenal aneurysms requiring only TAMBE System. Hypothesis-driven analysis. Up to 65 additional subjects may be implanted in Continued Access Phase under the Primary Study Arm only Secondary Study Arm - TAAA requiring TAMBE System and CTAG Device(s). Non hypothesis-driven analysis. Minimum: 122 implanted subjects. Maximum: 202 implanted subjects with up to 65 additional subjects implanted... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
01/18/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Thoracoabdominal Aortic Aneurysm
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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
NCT02493478
Recruiting
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
Gender:
All
Ages:
All
Trial Updated:
01/17/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
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RISE: A Remote Study of Insomnia Treatment in Crohn's Disease
NCT05956158
Recruiting
The purpose of this study is to assess whether the investigators can treat insomnia in people with Crohn's disease, and if insomnia treatment can make other things better, like pain or inflammation.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Insomnia, Crohn Disease
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Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
NCT02089217
Recruiting
Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical ma... Read More
Gender:
All
Ages:
Between 35 years and 100 years
Trial Updated:
01/12/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Carotid Stenosis
Register for Updates
Pulse-Width Modulation
NCT06120231
Recruiting
The overarching aim of this project is to modulate the pulse-width during stimulation of pedicle screws and record the response thresholds associated with each PWM setting. During this initial phase of the investigation, no further data will be collected.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: Dartmouth-Health, Lebanon, New Hampshire
Conditions: Spinal Fusion, Spinal Stenosis
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Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases
NCT05438212
Recruiting
This phase III trial compares the addition of stereotactic radiosurgery before or after surgery in treating patients with cancer that has spread to the brain (brain metastases). Stereotactic radiosurgery is a type of radiation therapy that delivers a high dose of radiation only to the small areas of cancer in the brain and avoids the surrounding normal brain tissue. Surgery and radiation may stop the tumor from growing for a few months or longer and may reduce symptoms of brain metastases.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2024
Locations: Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Conditions: Metastatic Malignant Neoplasm in the Brain
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Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
NCT05095376
Recruiting
This phase III trial compares the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. Chemotherapy drugs, such as lomustine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy photons to kill tumor cells and s... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
01/09/2024
Locations: Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Conditions: Glioblastoma, Gliosarcoma
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Phase 1 Study to Assess Safety and Efficacy of ANG003
NCT06052293
Recruiting
Randomized, parallel, active-treatment Phase 1 study of a single dose of orally administered ANG003 with a test meal in adult subjects with cystic fibrosis-related exocrine pancreatic insufficiency. The study's overall objectives are to evaluate the safety, tolerability and effect of four dose levels of ANG003.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Exocrine Pancreatic Insufficiency
Register for Updates
Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function
NCT04763200
Recruiting
The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart function and health after a heart procedure compared to the current standard of care.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
12/29/2023
Locations: Catholic Medical Center, Manchester, New Hampshire
Conditions: Left Ventricular Dysfunction, Coronary Artery Disease
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Characterizing In Vivo Oral Lesion Impedances
NCT05430477
Recruiting
The primary objective of this study is to demonstrate a significant difference in electrical impedance between normal, benign, premalignant, and malignant oral lesions using a custom device. The secondary study objective is to create a database of in vivo electrical impedance spectra and images of oral lesions. This will be achieved by collecting Electrical Impedance sensing data and images from two cohorts of patients: Cohort I will consist of 200 patients undergoing oral lesion biopsies and Co... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/21/2023
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Oral Lesion
Register for Updates