There are currently 41 active clinical trials seeking participants for COPD research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and South Carolina.
A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD
NCT04320342
Recruiting
The purpose of this study is to compare CHF 5993 with CHF 1535 in improving lung function, reducing moderate and severe COPD exacerbations, and other clinical efficacy and safety outcomes in the target subject population.
Gender:
All
Ages:
40 years and above
Trial Updated:
04/12/2024
Locations: Chiesi Clinical Trial Site 840350, Birmingham, Alabama +396 locations
Conditions: COPD, COPD Exacerbation
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Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)
NCT04901455
Recruiting
This study will determine the functional status of the nasal immune environment with LAIV exposure in COPD persons with frequent exacerbations (defined as individuals with two or more episodes of worsening in COPD symptoms requiring treatment with antibiotics and/or steroids in the prior 12 months) and COPD persons without frequent exacerbations to determine acute exacerbation of COPD (AECOPD)-associated dysfunction in a) cytokines and immune effector cells of the nasal mucosa and b) viral repli... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
04/11/2024
Locations: Eastowne Medical Office Building, Chapel Hill, North Carolina
Conditions: COPD
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Effect of Ensifentrine on Sputum Markers of Inflammation in COPD
NCT05270525
Recruiting
This is a randomized, double-blind, placebo-controlled, two-period cross-over study of nebulized ensifentrine (3 mg) or placebo administered BID for two 8-week Treatment Periods. All participants with receive both ensifentrine and placebo during participation. There are 7 in-clinic visits over a total duration of up to 24 weeks participation.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
04/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: COPD
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Impairments That Affect Correct Inhaler Use in COPD
NCT06135324
Recruiting
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic obstructive pulmonary disease (COPD). Assess the relationship of cognitive impairment and impaired manual dexterity with patient errors using current pMDIs, SMIs and/or DPIs.
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
03/21/2024
Locations: University of Alabama at Birmingham - Lung Health Center, Birmingham, Alabama +3 locations
Conditions: COPD
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The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)
NCT06152653
Recruiting
The goal of this clinical trial is to determine if positive pressure during inspiration will improve penetration of aerosolized N-Acetylcysteine (NAC) into airway mucus plugs in the lungs of patients with asthma or Chronic Obstructive Pulmonary Disease (COPD). The main questions it aims to answer are: Does delivery of aerosolized NAC with positive inspiratory pressure have a greater effect on mucus plug burden in the lungs than delivery of NAC without positive pressure. Does delivery of aeroso... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
03/15/2024
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma, COPD
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Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT
NCT05040386
Recruiting
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in older Americans. COPD increases in frequency with age, and older adults with COPD often have significant unmet geriatrics-palliative care needs that results in reduced quality of life, high healthcare utilization, and care at the end of life that does not align with the values and wishes of patients and their care partners. Older adults with COPD could benefit from proactive geriatrics-palliative care before the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: COPD
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Telehealth and Onsite Maintenance Exercise in COPD
NCT06304207
Recruiting
The goal of this pilot clinical trial is to compare telehealth and onsite supervised maintenance exercise program for adults with COPD. The specific aims of the study are: To compare 8-week supervised maintenance program delivered onsite and via tele-rehab with no maintenance for patients with COPD following discharge from traditional exercise or physical therapy or onsite outpatient rehabilitation programs on clinical outcomes (dyspnea, exercise capacity, physical function, physical activity,... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
03/04/2024
Locations: MGH Institute of Health Professions, Charlestown, Massachusetts
Conditions: Copd, COPD Exacerbation, COPD Bronchitis
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Heat Waves and the Elderly With COPD
NCT06295523
Recruiting
The purpose of this study is to investigate thermoregulatory responses in older individuals with COPD.
Gender:
All
Ages:
65 years and above
Trial Updated:
03/04/2024
Locations: Texas Health Presbyterian Hospital Dallas, Dallas, Texas
Conditions: COPD, Aging, Hyperthermia
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The Reducing REVISITS Study: A Cluster RCT
NCT05568043
Recruiting
This type II hybrid effectiveness-implementation trial will concurrently study the comparative effectiveness of virtual vs. in-person COPD care transition programs implemented via virtual mentored implementation approaches with and without co-design methods. The investigators will enroll up to 24 randomized sites (with a goal minimum of 16 sites) to: Deliver the COPD programs implemented via mentored support in collaboration with SHM Center for Quality Improvement. Compare the effectiveness an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: COPD, COPD Exacerbation Acute
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4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting
NCT04786171
Recruiting
This study will investigate the utility of 4D Medical's X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained utilizing this technique.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Copd, Emphysema, Hyperinflation
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A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD
NCT06003049
Recruiting
The aim of this clinical trial to determine the safety and effectiveness of treating the COPD symptoms with subcutaneous BOTOX injections in participants with moderate COPD.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/29/2024
Locations: Tranquil Clinical Research, Webster, Texas
Conditions: COPD
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The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
NCT05701982
Recruiting
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi mindfulness intervention can improve physical function in Veterans with COPD and chronic musculoskeletal pain. The proposed research addresses VA Rehabilitation R&D Service's high priority area of improving health-related quality of life by reducing disease burden and maximi... Read More
Gender:
All
Ages:
Between 40 years and 100 years
Trial Updated:
01/25/2024
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: COPD, Chronic Musculoskeletal Pain
Register for Updates