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Pain Paid Clinical Trials in North Carolina
A listing of 62 Pain clinical trials in North Carolina actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
49 - 60 of 62
The state of North Carolina currently has 62 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Durham, Winston-Salem, Charlotte and Chapel Hill.
Featured Trial
Bipolar Disorder Study (Medicare Required)
Recruiting
Non-drug Bipolar Depression study for adults with Medicare. If you have Bipolar Disorder, are over the age of 18, and are currently depressed, you may be eligible to take part in this study. If you have tried at least four treatments and not found them helpful, you are a good candidate for this study. All study-related care will be provided at no cost to you.
Conditions:
Bipolar Disorder
Bipolar Depression
Bipolar I Disorder
Depression
Bipolar
Featured Trial
Depression Clinical Studies
Recruiting
Need new medication for depression? Help us study an investigational medication to potentially help people with MDD. Qualified participants may receive reasonable compensation for trial-required travel expenses.
Conditions:
Major Depressive Disorder
Major Depression
Major Depressive Episode
Major Depressive Disorder (MDD)
Major Depressive Disorder
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
Child/Teen Migraine
Recruiting
The study is evaluating an investigational product for the treatment of migraine in children the ages of 6 to 17. The investigational product is currently approved to treat migraines in adults.
The Pain Intervention Via Video Optimization Trial
Recruiting
This project tests a brief evidence-based video to help educate patients regarding effective and safe pharmacologic and non-pharmacologic therapies for acute musculoskeletal pain (MSP). Subjects will be randomly placed into one of two study arms: intervention (educational video) and usual care. Patients will be contacted at baseline and at 1 and 3 months after the date of an emergency department (ED) or urgent care encounter for follow-up. The aim of this study is to evaluate the success of the... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/30/2023
Locations: University of North Carolina Hospitals, Chapel Hill, North Carolina
Conditions: Acute Musculoskeletal Pain, Chronic Pain
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Recruiting
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Gender:
All
Ages:
18 years and above
Trial Updated:
11/22/2023
Locations: Wake Forest, Winston-Salem, North Carolina
Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
Investigation of PEMF Therapy for Female Patients With IC/BPS
Recruiting
The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy. The study team will distribute the PEMF device to female adults with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) to measure its ability to decrease bladder and pelvic pain as well as other urinary symptoms associated with IC/BPS. There are two sequential Aims in this study a... Read More
Gender:
Female
Ages:
Between 18 years and 80 years
Trial Updated:
10/24/2023
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis Pain
Recruiting
This is dose-finding study of GSK3858279 in participants with moderate to severe knee osteoarthritis (OA) pain. The purpose of this study is to investigate and provide the data necessary to select the optimal effective and safe dose(s) of GSK3858279.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
10/11/2023
Locations: GSK Investigational Site, Greensboro, North Carolina
Conditions: Pain
Mobile Neurofeedback for Low Back Pain
Recruiting
The purpose of this study is to learn more about improving the quality of treatments for people who have chronic low back pain. Participants will complete interviews with Duke researchers at four different time points: the beginning of the study, at 3 months, at 6 months, and at 9 months. Participants will be asked to use a mobile app and a headset that are designed to train the brain to be more relaxed. Participants will use the mobile app for 10 minutes at a time, four times a week for three m... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
10/10/2023
Locations: Duke University Medical Center, Department of Psychiatry, Durham, North Carolina
Conditions: Chronic Low Back Pain
Well-Being After Breast Cancer Surgery
Recruiting
The purpose of this study is to compare the benefits of skills training and health education interventions designed specifically to increase the well-being of people with persistent pain after breast surgery for lobular carcinoma in situ (LCIS), ductal carcinoma in situ (DCIS), or invasive breast cancer, and to examine the roles of psychological and physiological variables as modifiable contributors to the continuing burden of persistent pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: General Health Education, Coping Skills Training for Persistent Post-Surgical Pain
Defining a PK and PD Model for Peripheral Analgesia After IV Oxytocin
Recruiting
The goal of this clinical trial is to learn about oxytocin ( a naturally occurring hormone made in the brain that transmits messages) and the effects it may have on thermal heat pain after intravenous administration. The main question it aims to define is the time course of change in pain score after a 5 minute heating of the skin administered at intervals during and following infusion of intravenous oxytocin in order to create a Pharmacokinetic and a Pharmacodynamic model for oxytocin-induced a... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/23/2023
Locations: Wake Forest Baptist Health, Winston-Salem, North Carolina
Conditions: Acute Pain, Chronic Pain, Healthy Volunteer
TENS and Perioperative Fracture Patients
Recruiting
This is a pilot study designed to evaluate the effectiveness of TENS as part of post-operative pain management. Subjects receiving a TENS unit as part of clinical practice will be approached for consent and followed for 12 months.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/14/2023
Locations: Carolinas Medical Center, Department of Orthopaedic Surgery, Charlotte, North Carolina
Conditions: Musculoskeletal Pain
Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy
Recruiting
Assess the safety and effectiveness of Axon Therapy in the treatment of chemotherapy-induced neuropathy
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
07/05/2023
Locations: Carolinas Pain Institute and Center for Clinical Research, Winston-Salem, North Carolina
Conditions: Neuralgia, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic Neuropathy
Recruiting
The purpose of this post-market study is to evaluate changes in pain and neurological function with high frequency, 10 kHz spinal cord stimulation (SCS) therapy in patients with chronic, intractable lower limb pain associated with diabetic peripheral neuropathy, a condition known as painful diabetic neuropathy (PDN). This is a multi-center, prospective, randomized controlled study to evaluate improvement in pain and neurological function in PDN patients, with neurological function assessed via o... Read More
Gender:
All
Ages:
22 years and above
Trial Updated:
05/09/2023
Locations: Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina
Conditions: Painful Diabetic Neuropathy
Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Recruiting
Real-world clinical practice multicenter study to determine the clinical implications of employing PCR/NGS technology to identify and treat potential urinary pathogens in female participants identified with bladder pain and/or cystitis-like symptoms.
Gender:
Female
Ages:
Between 18 years and 80 years
Trial Updated:
03/13/2023
Locations: Wake Forest University Baptist Medical Center Urology, Winston-Salem, North Carolina
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
Recruiting
To study the response of objective and quasi-objective 'True' functional outcomes, analgesia and safety in chronic non-radicular back pain to buprenorphine buccal film (BBF) using a small 'n' phase IV design. To assess associations between traditional pain relevant subjective outcomes and objective or quasi-objective functional outcomes; In a small 'n' construct, to assess more powerful, 'new' statistical methods (e.g. hierarchical linear models, joint trajectory analysis) compared to traditiona... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/06/2023
Locations: Carolinas Pain Institute, Winston-Salem, North Carolina
Conditions: Back Pain Lower Back Chronic, Chronic Pain
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