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Pain Paid Clinical Trials in North Carolina
A listing of 62 Pain clinical trials in North Carolina actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
25 - 36 of 62
The state of North Carolina currently has 62 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Durham, Winston-Salem, Charlotte and Chapel Hill.
Featured Trial
Bipolar Disorder Study (Medicare Required)
Recruiting
Non-drug Bipolar Depression study for adults with Medicare. If you have Bipolar Disorder, are over the age of 18, and are currently depressed, you may be eligible to take part in this study. If you have tried at least four treatments and not found them helpful, you are a good candidate for this study. All study-related care will be provided at no cost to you.
Conditions:
Bipolar Disorder
Bipolar Depression
Bipolar I Disorder
Depression
Bipolar
Featured Trial
Depression Clinical Studies
Recruiting
Need new medication for depression? Help us study an investigational medication to potentially help people with MDD. Qualified participants may receive reasonable compensation for trial-required travel expenses.
Conditions:
Major Depressive Disorder
Major Depression
Major Depressive Episode
Major Depressive Disorder (MDD)
Major Depressive Disorder
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
Child/Teen Migraine
Recruiting
The study is evaluating an investigational product for the treatment of migraine in children the ages of 6 to 17. The investigational product is currently approved to treat migraines in adults.
Pilot Trial of an Online Pain Coping Skills Training Program in Spanish
Recruiting
The goal of this pilot study is to assess the feasibility and acceptability of an 8-week online pain coping skills training program designed specifically for Spanish-speaking Hispanic and Latine populations experiencing cancer-related pain. The main questions aim to answer are: 1. what is the feasibility of this program for engaging and recruiting Spanish speaking members of the Hispanic and Latine community?; 2. How well is the program accepted by Spanish speaking members of the Hispanic and La... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Cancer Pain
Implementation of the ACP Guideline for Low Back Pain (IMPACt-LBP)
Recruiting
The purpose of this study is to assess whether the primary spine practitioner (PSP) model of care will lead to improvements in patient outcomes, as compared to usual care, based on change in patient-reported PROMIS Pain Interference and Physical Function from baseline to 3 months in patients aged 18 years and older with a primary complaint of low back pain (LBP).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Duke Health, Durham, North Carolina
Conditions: Pain, Back
Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy
Recruiting
The objective of this study is to conduct a randomized clinical trial to evaluate an opioid versus an opioid-free pathway of perioperative use of ketamine, ketorolac, and IV acetaminophen followed by the postoperative use of ketorolac, and oral acetaminophen for pain associated with robotic-assisted radical prostatectomy. Escalation to use of opioid treatment for the opioid-free constituents will be available if needed.
Gender:
Male
Ages:
Between 40 years and 75 years
Trial Updated:
04/17/2024
Locations: Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain
Recruiting
To be eligible for the trial, subjects must have ongoing moderate to severe neuropathic pain related to a prior course of platinum and/or taxane chemotherapy and have no clinical evidence of actively progressive disease.
The trial period will comprise a Screening period (up to 35 Days), randomization and a 4-day treatment period, followed by a 12-week follow up period (12 weeks total after initial treatment), and an End-of-Trial/Follow-up visit which will occur at Week 13. This is a study to re... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
04/05/2024
Locations: Oncology Specialists of Charlotte, Charlotte, North Carolina
Conditions: Chemotherapy-induced Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia
Recruiting
The main goal of this clinical trial is to test benefits of completing online pain coping skills training program in women who have been diagnosed with stage I-III breast cancer, who have completed their primary cancer treatment, who are taking an AI medication, and who have arthralgia. Arthralgia is a type of joint, bone, and muscle pain that is a common side effect of AI medications. The main questions it aims to answer are:
Whether online pain coping skills training reduces the severity of p... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: Duke University, Durham, North Carolina
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
Recruiting
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the study participants, and all research staff (except the principal investigator), combined with a series of 3 injections of Platelet-Rich Plasma (PRP) into an osteoarthritic knee joint, leads to reductions in knee pain, and improvements in physical function. Improvements will... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/01/2024
Locations: QC Kinetix Franchise Group, LLC, 309 South Sharon Amity Rd, Ste 302, Charlotte, North Carolina
Conditions: Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Trial Updated:
03/29/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina +1 locations
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
VIA Disc NP Registry 3.0
Recruiting
Registry is to observe and trend patterns of care and outcomes for patients treated with VIA Disc NP.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Premier Pain Solutions, Asheville, North Carolina +1 locations
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
Recruiting
VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes. Approximately 50% of all US Veterans have chronic pain, and CLBP is the most common type of pain in this population. This study will use a sequential randomized, pragmatic, 2-step comparative effectiveness study design. The main goal is to identify the best approach for treating cLBP using commonly recommended non-surgical and non-pharmacological options. The... Read More
Gender:
All
Ages:
All
Trial Updated:
03/21/2024
Locations: Asheville VA Medical Center, Asheville, NC, Asheville, North Carolina
Conditions: Chronic Low Back Pain
Regional Anesthesia Following Pediatric Cardiac Surgery
Recruiting
The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.
Gender:
All
Ages:
17 years and below
Trial Updated:
03/20/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Atrial Septal Defect, Ventricular Septal Defect, Pain, Procedural
Use of Dermabond in Mitigation of Spinal Cord Stimulation (SCS) Trial Lead Migration
Recruiting
During the typical SCS trial the leads remain outside of the skin and can be prone to migration. The leads are typically secured in place with suture, tape, or a combination of both. This study will evaluate the amount of movement based on the method of being secured at the time of placement
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Chronic Pain
GI Alpha-Gal Study
Recruiting
This is a double-blind, crossover food challenge study using pork with and without α-gal in patients with a clinical diagnosis of gastrointestinal (GI)- α-gal allergy, and to investigate the pathophysiology underlying their symptoms.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Alpha-Gal Syndrome, Irritable Bowel Syndrome, Diarrhea, Abdominal Pain, Vomiting
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