CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer
NCT05210283
Recruiting
The CORRECT - MRD II study will prospectively enroll patients who have undergone complete surgical resection for stage II or III colorectal cancer. Patients will be followed for a minimum of 3 years and up to 5 years for recurrence.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/01/2023
Locations: Sanford NCORP of the North Central Plains, Fargo, North Dakota
Conditions: Colorectal Cancer
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Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease
NCT05202509
Recruiting
This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/27/2023
Locations: Lillestol Research LLC, Fargo, North Dakota
Conditions: Atherosclerotic Cardiovascular Disease
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Safety of Extending The Routine Flushing Of Implanted Port Devices From 4 Weeks To 12
NCT05454189
Recruiting
Implanted port devices (IPD) play an essential role in the safe administration of cancer treatments by providing a device to safely administer caustic chemotherapy agents. The current recommended frequency of flushing the IPD per manufacturers guidelines is every 4-6 weeks. The purpose of this study is to find out if extending IPD flushes to every 12 weeks is safe and if it is just as effective as every 4 week flushing.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/06/2023
Locations: Essentia Health Fargo, Fargo, North Dakota
Conditions: Maintenance of Implanted Port Devices
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SH Dr. Chen Gastric Bypass Study
NCT05357443
Recruiting
Evaluation of serum gastrin levels and their effect on marginal ulcer formation.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/26/2022
Locations: Sanford Health, Fargo, North Dakota
Conditions: Gastric Bypass
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Evaluating the Safety and Efficacy of a Novel Accelerated Partial Breast Irradiation Regimen for patIents With Favorable Risk breaSt cancEr
NCT05591547
Recruiting
This study will use an adjuvant radiation therapy regimen called APBI (accelerated partial breast irradiation). APBI is a treatment option available to women considered to have an early stage, low-risk breast cancer. The standard external beam-based APBI treatment delivers treatments every other day for five treatments, over ten calendar days. The APBI in this study is modified and will deliver five once daily treatments over consecutive treatment days, with a slightly lower dose of radiation ea... Read More
Gender:
Female
Ages:
50 years and above
Trial Updated:
11/11/2022
Locations: Sanford Health, Fargo, North Dakota
Conditions: Breast Cancer
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Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
NCT04625647
Recruiting
This phase II Lung-MAP treatment trial studies the effect of AMG 510 in treating non-squamous non-small cell lung cancer that is stage IV or has come back (recurrent) and has a specific mutation in the KRAS gene, known as KRAS G12C. Mutations in this gene may cause the cancer to grow. AMG 510, a targeted treatment against the KRAS G12C mutation, may help stop the growth of tumor cells.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/09/2022
Locations: Sanford Bismarck Medical Center, Bismarck, North Dakota
Conditions: Lung Adenocarcinoma, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Squamous Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
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Bentracimab (PB2452) in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure
NCT04286438
Recruiting
This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with bentracimab (PB2452) in patients who present with uncontrolled major or life-threatening bleeding or who require urgent surgery or invasive procedure. At least 200 patients will be enrolled from approximately 200 centers in North America, Europe, and Asia-Pacific regions, including mainland China. Patients with reported use of ticagrelor within the prior 3 days who require... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2022
Locations: Sanford Medical Center Fargo, Fargo, North Dakota
Conditions: Hemorrhage, Urgent Surgery, Invasive Procedure
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Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
NCT05135286
Recruiting
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
Gender:
All
Ages:
Between 45 years and 80 years
Trial Updated:
09/30/2022
Locations: Visus Therapeutics Investigative Site, W. Fargo, North Dakota
Conditions: Presbyopia
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Direct Resuscitation of the Open Peritoneum
NCT04887480
Recruiting
The DROP trial evaluates two ways of treating patients whose abdomens are left open after their abdominal surgery. The current standard of care at Sanford is for patients to have their wound covered with a sterile dressing connected to a vacuum with suction, which removes fluid from the abdomen. In this trial, we are evaluating the benefits of adding dialysis fluid to the abdomen periodically, prior to suctioning it out with the vacuum system. This trial will show if the addition of this fluid l... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/13/2022
Locations: Sanford Medical Center Fargo, Fargo, North Dakota
Conditions: Wound; Abdomen, Abdomen, Acute, Wound Surgical
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Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Mild Cognitive Impairment (tDCS)
NCT03191916
Recruiting
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left dorsolateral prefrontal cortex (LDLPFC) will induce long-lasting effects in improving cognitive function and reducing cognitive fatigue and fatigability in PD patients with MCI.
Gender:
All
Ages:
All
Trial Updated:
11/29/2021
Locations: Sanford Brain & Spine Center, Fargo, North Dakota
Conditions: Parkinson Disease, Mild Cognitive Impairment
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Outcomes of a Trifocal IOL in Post-refractive Patients
NCT04545073
Recruiting
To compare the prediction error of ORA vs formula for post-LASIK cataract patients when PanOptix IOL was implanted. Using post-operative outcomes to determine if preoperative IOL calculations, including Barrett TK, Barrett Universal II, Hill RBF, ASCRS post-refractive calculator, or intraoperative aberrometry is more accurate when the two methods disagree in patients who have had previous refractive surgery undergo cataract surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/15/2020
Locations: Vance Thompson Vision ND, W. Fargo, North Dakota
Conditions: Refractive Errors
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DEXTENZA Compared to Topical Prednisolone in Patients Undergoing Bilateral LASIK Surgery
NCT04281862
Recruiting
To determine patient preference and treatment outcomes with an intracanalicular dexamethasone (0.4mg) insert compared to standard steroid drop regimen in the contralateral eye following bilateral LASIK surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/19/2020
Locations: Vance Thompson Vision ND, W. Fargo, North Dakota
Conditions: Refractive Surgery
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