There are currently 66 active clinical trials seeking participants for Insomnia research studies. The states with the highest number of trials for Insomnia participants are California, Florida, Texas and Ohio.
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
NCT05390918
Recruiting
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change strategies for adolescents at risk of suicidal behavior who suffer from difficulties falling asleep, staying asleep, and/or insufficient sleep.
Gender:
All
Ages:
Between 11 years and 18 years
Trial Updated:
02/15/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Insomnia, Suicidal Ideation, Suicide, Attempted
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Brief Cognitive Behavioral Therapy to Enhance Benzodiazepine Deprescribing
NCT06119308
Recruiting
The goal of this clinical trial is to conduct a single-arm pilot trial of a brief cognitive-behavioral therapy-enhanced benzodiazepine deprescribing intervention in 20 older adults (aged ≥55 years) prescribed chronic benzodiazepines by their primary care clinicians.
Gender:
All
Ages:
55 years and above
Trial Updated:
06/20/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Benzodiazepine Use, Insomnia, Anxiety
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Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use
NCT05814822
Recruiting
This study will compare the efficacy of telemedicine-delivered cognitive behavioral therapy for insomnia tailored for people using cannabis for sleep (CBTi-CB-TM) to telemedicine-delivered sleep hygiene education (SHE-TM) on sleep, cannabis use, and daytime functioning. We will also evaluate the effects of CBTi-CB-TM on fundamental sleep regulatory system - homeostatic sleep drive - and its association with clinical outcomes.
Gender:
All
Ages:
21 years and above
Trial Updated:
06/20/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Insomnia
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Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia Disorder
NCT05423717
Recruiting
This study assesses the efficacy, safety, and pharmacokinetics of multiple-dose oral administration of daridorexant in pediatric subjects aged 10 to < 18 years with insomnia disorder.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/20/2024
Locations: Banner - University Medical Center Tucson, Tucson, Arizona +40 locations
Conditions: Insomnia
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Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
NCT05516277
Recruiting
This pilot randomized controlled trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of another condition, in the context of PTSD in understudied older adults. This study provides a non-medication treatment for PTSD called Cognitive Processing Therapy (CPT) followed by one of two non-medication sleep education and treatment programs for sleep p... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
06/12/2024
Locations: VA Greater Los Angeles Healthcare System, North Hills, California
Conditions: Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
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Sleep and Pain Interventions in Women With Fibromyalgia
NCT03744156
Recruiting
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia. This trial will yield important information about the roles of sleep, arousal, and brain structure and function in the development and maintenance of chronic pain in women with fibromyalgia.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: University of Missouri- Department of Psychiatry, Columbia, Missouri
Conditions: Fibromyalgia, Insomnia, Chronic Widespread Pain
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Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
NCT06281756
Recruiting
Individuals who have insomnia with short sleep duration (ISS) differ from individuals who have insomnia with normal sleep duration (INS) in terms of health risks (i.e., hypertension) and treatment response. This study will examine whether patients with ISS and INS demonstrate a differential response to two common insomnia treatments. One is behavioral, Cognitive Behavioral Therapy for Insomnia (CBT-I). The other is a widely prescribed, non-habit-forming medication, trazodone used at a low dose.... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: National Jewish Health, Denver, Colorado +3 locations
Conditions: Insomnia, Insomnia Chronic, Insomnia, Primary, Blood Pressure, Blood Pressure, High
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National Adaptive Trial for PTSD Related Insomnia
NCT03668041
Recruiting
Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone or eszopiclone can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memories, difficu... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/07/2024
Locations: Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama +34 locations
Conditions: Insomnia
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A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors
NCT06392789
Recruiting
This clinical trial evaluates the effect of conversational agent, Cecebot, on improving insomnia in stage I-III breast cancer survivors. Sleep disturbance ranks among the top concerns reported by breast cancer survivors and is associated with poor quality of life. Many breast cancer survivors also have decreased physical activity, which may also have a negative impact on sleep and quality of life. Cognitive behavioral therapy for insomnia (CBTi) and physical activity interventions have individua... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Insomnia
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Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)
NCT05457790
Recruiting
Research Type: Clinical Trial Background: People with sickle cell disease (SCD) have many health challenges. Also, they often have trouble sleeping. Acceptance and commitment therapy (ACT) might help people with SCD to improve their sleep problems. Objective: To see how well ACT works in people with SCD and sleep problems and to find out how they feel about it. Eligibility: People between the ages of 18 and 55 with SCD and trouble sleeping. Design: The study is remote. Participants will... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/04/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Sickle Cell Disease, Sickle Cell Anemia, Insomnia, Sleeplessness, Transient Insomnia, Nonorganic Insomnia, Chronic Insomnia
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The Impact of Insomnia on Pain in HIV
NCT04298658
Recruiting
The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2) if weekly fluctuations in insomnia burden drive changes in inflammation, pain severity, and physical functioning in people living with HIV. This research could help confirm insomnia as a therapeutic... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/03/2024
Locations: UAB, Birmingham, Alabama
Conditions: HIV, Insomnia
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Digital CBT for Insomnia and Depression
NCT05456607
Recruiting
This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: University of Rochester Sleep Research Laboratory, Rochester, New York
Conditions: Depression, Insomnia
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