There are currently 13 active clinical trials seeking participants for Diabetic Macular Edema research studies. The states with the highest number of trials for Diabetic Macular Edema participants are Texas, California, Florida and New York.
Assessment of Retinal Fundus Imaging Camera
NCT06173232
Recruiting
The goal of this prospective study is to evaluate device performance when using fundus images taken from retinal fundus cameras in subjects with and without diabetic retinopathy per ETDRS level 35 and higher with or without macular edema.
Gender:
All
Ages:
22 years and above
Trial Updated:
12/07/2023
Locations: Midwest Eye Center, Cincinnati, Ohio
Conditions: Diabetic Retinopathy, Diabetic Macular Edema
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Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial
NCT05610319
Recruiting
This study will assess a pragmatic, treat and extend regimen of faricimab against the standard of a fixed dosing regimen.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Retinal Consultants Medical Group Inc., Modesto, California +48 locations
Conditions: Diabetic Macular Edema
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Evaluation of Tonabersat for DME
NCT05727891
Recruiting
This randomized clinical trial will evaluate the effect of tonabersat compared with placebo on central subfield thickness (CST) in eyes with center-involved diabetic macular edema (CI-DME) and good visual acuity.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/04/2024
Locations: Retina Associates of Southern California, Huntington Beach, California +24 locations
Conditions: Diabetic Macular Edema
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A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
NCT05224102
Recruiting
This study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hispanic/Latino American, or Native American/Alaska Native/Native Hawaiian or other Pacific Islander; in addition, a cohort of Asian Indian participants will be enrolled in India.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Barnet Dulaney Perkins Eye Center, Mesa, Arizona +50 locations
Conditions: Diabetic Macular Edema
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A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
NCT05476926
Recruiting
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products (Faricimab and Port Delivery System with Ranibizumab) in approved retinal indications (neovascular age-related macular degeneration... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Retinal Research Institute, LLC, Phoenix, Arizona +176 locations
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
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Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)
NCT06011798
Recruiting
The goal of this clinical trial is to assess the efficacy and safety of multiple doses of foselutoclax (UBX1325) in patients with Diabetic Macular Edema. The main questions the study aims to answer are: Assess the efficacy of foselutoclax compared to aflibercept Assess the safety and tolerability of foselutoclax
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: California Retina Consultants, Bakersfield, California +20 locations
Conditions: Diabetic Macular Edema, Retinal Disease, Macular Edema, Diabetes Mellitus, Diabetic Retinopathy, Retinal Degeneration, Retinal Diseases, Eye Diseases, Edema
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Safety and Effect of Intravitreal Injection of a Derivative of Nucleoside Reverse Transcriptase Inhibitor in Subjects With Diabetic Macular Edema
NCT05699759
Recruiting
This study is designed to assess the safety and initial evidence of efficacy of the novel compound SOM-401 (K8), a derivative of a nucleoside reverse transcriptase inhibitor, in subjects with untreated, clinically significant, diabetic macular edema (DME).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Diabetic Macular Edema
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Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema (DIAMOND-2)
NCT06172257
Recruiting
The primary objective is to evaluate the efficacy and safety of OCS 01 as compared to Vehicle in subjects with Diabetic Macular Edema (DME).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
03/05/2024
Locations: Oculis Investigative Site - Sierra Eye Associates, Reno, Nevada
Conditions: Diabetic Macular Edema
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Effect of AIV007 by Periocular Administration in Subjects With nAMD or DME
NCT05698329
Recruiting
To determine safety, pharmacokinetics, and duration of effect of periocularly administered AIV007 gel suspension in subjects with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME).
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
02/02/2024
Locations: Retina Consultants of Austin, Austin, Texas
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
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4D-150 in Patients With Diabetic Macular Edema
NCT05930561
Recruiting
Phase 2 randomized, active-controlled, double-masked, dose-ranging trial in adults with Diabetic Macular Edema (DME).
Gender:
All
Ages:
18 years and above
Trial Updated:
08/29/2023
Locations: National Ophthalmic Research Institute, Fort Myers, Florida +6 locations
Conditions: Diabetic Macular Edema, Diabetic Retinopathy
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Evaluation of Repeated, In-Clinic, Self-Imaging by DME Patients Using the Notal Vision Home OCT
NCT05745116
Recruiting
Evaluation of Repeated, In-Clinic, Self-Imaging by DME Patients Using the Notal Vision Home OCT The purpose of this study is to collect data on the NVHO device at up to three sites.
Gender:
All
Ages:
All
Trial Updated:
02/15/2023
Locations: Elman Retina Group, PA, Baltimore, Maryland +2 locations
Conditions: Diabetic Macular Edema
Register for Updates
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (AMD) or Subjects With Diabetic Macular Edema (DME)
NCT05387837
Recruiting
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in subjects with Neovascular (wet) Age-Related Macular Degeneration (AMD) or subjects with Diabetic Macular Edema (DME)
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: Lazar Retina, Los Angeles, California +11 locations
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Register for Updates