The city of Cleveland, Ohio, currently has 28 active clinical trials seeking participants for Pain research studies.
Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain
Recruiting
Investigators will evaluate preamputation cryoanalgesia on pain, mobility, opioid use and general physical and emotional disability using a pilot randomized trial design, to explore the amount and variability of improvement on those outcomes and to investigate the potentiality of conducting a future larger randomized controlled trial, which the investigators will assess quantitatively the benefits of cryoanalgesia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Postoperative Pain
Optimization of NIBS for Treatment of Addiction
Recruiting
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial assessments with active stimulation, when compared to sham stimulation.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/30/2024
Locations: University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit, Cleveland, Ohio
Conditions: Opioid-use Disorder, Chronic Pain
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
Recruiting
The study is a prospective, first-in-human, multi-center, non-randomized, single-arm study to assess the safety and efficacy of the CEM-Cage used with the CEM-Plate in patients who are appropriate candidates for a 2-level anterior cervical discectomy and fusion (ACDF). Fifty patients will be enrolled in the study and, after undergoing a 2-level ACDF, will be evaluated at 4 weeks, 3 months, 6 months, 12 months, 18 months, and 24 months.
Gender:
ALL
Ages:
Between 22 years and 79 years
Trial Updated:
11/01/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy, Spondylosis With Radiculopathy Cervical Region, Intervertebral Disc Disorder Cervical
Noninvasive Brain Stimulation for Diabetic Neuropathic Pain
Recruiting
This is an investigator-initiated study that is in the funding range for a grant from the NIH. This study is testing the possibility that non-invasive brain stimulation (ESSTim) would be superior to sham in the treatment of pain secondary to diabetic neuropathy.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
07/19/2022
Locations: University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit, Cleveland, Ohio
Conditions: Diabetic Neuropathies, Chronic Pain