There are currently 651 clinical trials in Charleston, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including Medical University of South Carolina, GSK Investigational Site, Hollings Cancer Center at Medical University of South Carolina and Medical University of South Carolina (MUSC). Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
Recruiting
This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the knee.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/01/2024
Locations: Clinical Trials of South Carolina, Charleston, South Carolina
Conditions: Knee Osteoarthritis
CARS: Cannabis and Alcohol Reduction Study
Recruiting
The study will test a computerized treatment with subjects ages 13-17 years who are seeking treatment for alcohol and/or cannabis use. Follow-up assessments will be conducted at one- and three-months following treatment.
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
02/01/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Cannabis Use, Alcohol Use, Unspecified, Substance Use, Substance Use Disorders
A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)
Recruiting
This is a 2-part, randomized, placebo-controlled, double-blind, Phase 2 study to evaluate the safety, tolerability, efficacy, and PK of RTA 901 in qualified subjects with DPNP. Each study part will be randomized into 3 treatment arms; 2 different doses of RTA 901 and a Placebo. The doses of RTA 901 in Part 2 will be selected based on the Exposure-Response (E-R) analyses of data from Part 1. A total of 384 subjects will be randomized in this study. Each part will have 192 subjects, with 64 subjec... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: WR-Notus Clinical Research, Charleston, South Carolina
Conditions: Diabetic Peripheral Neuropathic Pain
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
Recruiting
Vulvovaginal skin conditions, namely vaginal atrophy, lichen sclerosus, lichen simplex chronicus and lichen planus affecting the female adult population will be treated with a novel gel dressing to test the short- and long-term safety and efficacy of the device.
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: WR-Charleston Clinical Trials, LLC, Charleston, South Carolina
Conditions: Atrophic Vaginitis, Vaginal Atrophy, Genitourinary Syndrome of Menopause, Lichen Sclerosus of Vulva, Lichen Planus of Vulva, Lichen Simplex of Vulva (Disorder)
A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)
Recruiting
The purpose of this study is to evaluate the efficacy, safety and tolerability of treatment with EDIT-301 in adult and adolescent participants with severe sickle cell disease (SCD).
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
01/30/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Sickle Cell Disease, Hemoglobinopathies
Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp
Recruiting
The aim of this study is to test the safety. tolerability and efficacy of field-directed photodynamic therapy (PDT) with 10% aminolevulinic acid gel (Ameluz®, BF-200 ALA) in combination with one of the narrow spectrum red light RhodoLED lamps in comparison to vehicle treatment for actinic keratosis (AK) on the extremities and neck/trunk.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Clinical Research Center of the Carolinas, Charleston, South Carolina
Conditions: Actinic Keratoses
Feasibility Study- REVEAL 475 for Bevonescein-Assisted Nerve Visualization in Head & Neck Surgery
Recruiting
A feasibility study to evaluate the usability of the REVEAL 475 system in patients treated with bevonescein for nerve visualization during surgery.
Gender:
All
Ages:
16 years and above
Trial Updated:
01/30/2024
Locations: MUSC- Hollings Cancer Center, Charleston, South Carolina
Conditions: Head and Neck Surgery
Thin EBUS Pilot Study
Recruiting
This is a single-center pilot study at the Medical University of South Carolina (MUSC) to evaluate the safety and efficacy of the TCP-EBUS scope (Thin EBUS). This study will consist of a standard of care bronchoscopy and will be followed for approximately 3 months. While the device is not FDA approved, it is the same technology but a thinner version of the SCP-EBUS bronchoscope.
Gender:
All
Ages:
21 years and above
Trial Updated:
01/29/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Lung; Node
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
Recruiting
Study to evaluate the feasibility, safety and performance of the HighLife trans-septal Transcatheter Mitral Valve in patients with moderate-severe and severe mitral regurgitation who are at high risk for surgical treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Mitral Regurgitation
CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC
Recruiting
The objective of this study is to assess safety and efficacy of CAB-AXL-ADC in NSCLC
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Medical University of South Carolina- Hollings Cancer Center, Charleston, South Carolina
Conditions: Non-Small-Cell Lung Cancer
CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)
Recruiting
The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Medical University of South Carolina- Hollings Cancer Center, Charleston, South Carolina
Conditions: Non Small Cell Lung Cancer, Triple Negative Breast Cancer, Melanoma, Head and Neck Cancer
A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)
Recruiting
This is a prospective, multicenter, single arm study designed to evaluate the safety and efficacy of the Temporary Bare Spur Stent System (Spur Stent System).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/26/2024
Locations: Medical University of South Carolina (MUSC), Charleston, South Carolina
Conditions: Peripheral Arterial Disease, Critical Limb Ischemia