Arlington, TX Clinical Trials

A listing of Arlington, TX Clinical Trials actively recruiting patient volunteers.

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74 trials found

A Phase 3, Randomized, Double-Blind Study to Assess the Efficacy of Difamilast Ointment in Mild to Moderate AD

NCT05608343

This is a Phase 3 Double Blind multi-center study conducted at 40 US investigational sites to assess the efficacy and safety of Difamilast Ointment 1% in subjects ≥2 years of age with mild to moderate atopic dermatitis.

Conditions: Atopic Dermatitis

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen Planus

NCT05593432

The purpose of this study will be to evaluate efficacy and safety of Ruxolitinib cream in participants With Cutaneous Lichen Planus. This is randomized, double-blind, vehicle-controlled (DBVC) study with a DBVC period of 16 weeks followed by an open label period (OLE) period of 16 weeks.

Conditions: Cutaneous Lichen Planus

A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC)

NCT05577715

The aim of this study is to characterize the safety and tolerability of MORAb-202, and to assess the objective response rate in participants with previously treated, metastatic NSCLC AC.

Conditions: Carcinoma, Non-Small-Cell Lung

Exploring Virtual Reality Adventure Training Exergaming

NCT05563805

The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical and mental health outcomes.

Conditions: Physical Activity, Sedentary Behavior, Depression, Cognitive Function, Post Traumatic Stress Disorder, Quality of Life, Heart Rate Variability, Anxiety
Phase: Not Applicable

A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)

NCT05514535

This study compares semaglutide, together with a lower dose of insulin glargine, to a higher dose of insulin glargine in participants with type 2 diabetes. The study looks at how well the study medicines control blood glucose levels. Participants will either get semaglutide together with a lower dose of insulin glargine or a higher dose of insulin glargine. The study will last for about 47 weeks (approximately 11 months). Participants will have 9 clinic visits, 15 phone/video calls and 1 home vi ...

Conditions: Diabetes Mellitus, Type 2, Obesity

Know and Own Your Movement-related Metrics Via Wearable Devices

NCT05490641

This study aims to promote daily physical activity in cancer survivors who are at high risk for type 2 diabetes (T2D) by using a personalized biological-based feedback strategy. T2D is one of the most common co-occurring conditions in cancer survivors and can worsen cancer-related health outcomes, especially in those who are insufficiently active. The investigators hypothesize that seeing the immediate impacts of exercise on their biological status will motivate cancer survivors to exercise. The ...

Conditions: Cancer, Survivorship
Phase: Not Applicable

A Study to Measure the Amount of Study Medicine in Blood in Adult Participants With COVID-19 and Severe Kidney Disease

NCT05487040

The purpose of this study is to learn about the side effects (safety) of the study medicine PF-07321332 (nirmatrelvir)/ritonavir for the treatment of mild to moderate COVID-19 infection in adults with severe renal impairment. The study will also look at the amounts of study drug in your blood. There will be 24 participants in this study; 12 of them will have severe renal impairment and not be on hemodialysis and 12 of them will be on hemodialysis. All participants in this study will take PF-073 ...

Conditions: COVID-19

Phase 2a To Evaluate PL-8177 in Subjects With Active Ulcerative Colitis (UC)

NCT05466890

PL8177 will be given orally once daily to adult ulcerative colitis patients. Patients meeting eligibility criteria will be randomized to receive either PL8177 or placebo (3:1) for a treatment period of 8 weeks followed by a 4-week post-treatment period.

Conditions: Ulcerative Colitis, Ulcerative Colitis Acute, Ulcerative, Ulcerative Colitis Flare

Study of Ruxolitinib Cream in Adolescents With Atopic Dermatitis

NCT05456529

The purpose of this study is to evaluate the long-term safety and tolerability of ruxolitinib cream in adolescents with Atopic Dermatitis (AD).

Conditions: Atopic Dermatitis (AD)

Study of ATI-1777 in Patients 12 to 65 Years Old With Moderate or Severe Atopic Dermatitis

NCT05432596

This is a Phase 2b study to determine the safety, tolerability, pharmacokinetic (PK), and efficacy of ATI-1777 in patients 12 to 65 years old with moderate or severe Atopic Dermatitis. Eligible participants will apply either ATI-1777 or Vehicle Topical Solution once daily or twice daily for 4 weeks.

Conditions: Atopic Dermatitis

INSPIRE Trial for Abdominal Infections

NCT05423743

The INSPIRE Abdominal Infection Trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision medicine computerized physician order entry (CPOE) smart prompts providing the probability that a non-critically ill adult admitted with abdominal infection is infected with a resistant pathogen. Note: enrolled "subjects" represent 102 individual HCA Healthcare hospitals that have been randomized into 92 c ...

Conditions: Abdominal (ABD) Infection
Phase: Not Applicable

INSPIRE Trial for Skin and Soft Tissue Infections

NCT05423756

The INSPIRE Skin and Soft Tissue Infection trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision medicine computerized physician order entry (CPOE) smart prompts providing the probability that a non-critically ill adult admitted with skin and soft tissue infection is infected with a resistant pathogen. Note: enrolled "subjects" represent 102 individual HCA Healthcare hospitals that have bee ...

Conditions: Skin and Soft Tissue (SST) Infection
Phase: Not Applicable