Ulcerative Colitis Clinical Trials in Arlington, TX

A listing of Ulcerative Colitis Clinical Trials in Arlington, TX actively recruiting patient volunteers.

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Ulcerative Colitis
2 trials found

Phase 2a To Evaluate PL-8177 in Subjects With Active Ulcerative Colitis (UC)


The purpose of this study is to compare PL8177 (a melanocortin receptor agonist) to placebo (in a 3:1 ratio-meaning that for every 3 people that get the active drug, one will receive placebo). The study treatment will be for 8 weeks. The study will measure safety and the body's ability to handle PL8177 and look at the improvement and healing of the intestine after 8 weeks of treatment. The study will include adult males and nonpregnant, nonlactating females with acute Ulcerative Colitis (UC).

Conditions: Ulcerative Colitis, Ulcerative Colitis Acute, Ulcerative, Ulcerative Colitis Flare

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis


The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely active ulcerative colitis (UC) who previously received double-blind treatment (either etrasimod 2 mg per day or placebo) during participation in one of the qualified Phase 3 or Phase 2 double-blind, placebo-controlled parent studies including but not limited to: (APD334-301 [NCT03945188] or APD334-302 [NCT03996369] or APD334-210 [NCT04607837]).

Conditions: Ulcerative Colitis