There are currently 1488 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Motor Network Physiology
NCT04957095
Recruiting
The brain networks controlling movement are complex, involving multiple areas of the brain. Some neurological disorders, like Parkinson's disease (PD) and essential tremor (ET), cause abnormalities in these brain networks. Deep brain stimulation is a treatment that is used to treat these types of neurological diseases and is thought to help patients by modulating brain networks responsible for movement. Levodopa medication is also used to modulate this brain networks in patients with PD. The ove... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
08/07/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Parkinson Disease, Essential Tremor
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Effect of Transcutaneous Electrical Nerve Stimulation on Post-stroke Patients
NCT06541015
Recruiting
The subjects will be asked to attend minimum 15 separate sessions, 6 for testing changes in reflex behaviors, 3 for testing changes in the influence of descending motor tracts on spinal motor neurons, 3 for each testing functional movement in response to a trip event and cross-tilt walking adaptation pattern, as part of their participation in the research study. The estimated amount of time to enroll and collect the data for each of the subjects is four months' time. The data will be analyzed an... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/07/2024
Locations: University of Texas Medical Center, Dallas, Texas
Conditions: Hemiplegia and/or Hemiparesis Following Stroke, Anterior Circulation Stroke of Uncertain Pathology
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Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy
NCT06313749
Recruiting
The goal of this clinical trial is to show non-inferiority of the MIMS® device/procedure with Mitomycin-C, in terms of its surgical success rate, compared to trabeculectomy with Mitomycin-C in subjects diagnosed with primary open angle glaucoma, whose intraocular pressure is not controlled despite polypharmacy. Eligible screened participants will undergo the MIMS® procedure and will be followed for a period of 12 months in this single-arm study. Investigators will compare the results of this st... Read More
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
08/06/2024
Locations: Glaucoma Associates of Texas, Dallas, Texas
Conditions: Primary Open Angle Glaucoma, Open Angle Glaucoma
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ABTECT - Maintenance
NCT05535946
Recruiting
This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhi... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/06/2024
Locations: Baylor Scott and White, Dallas, Texas
Conditions: Ulcerative Colitis
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Non-Invasive Testing to Evaluate Wound Healing in Diabetes
NCT04232631
Recruiting
Normal group: We will collect normative data from healthy individuals to include baseline data, screening, and images. Up to 500 people will be enrolled and can include normal healthy volunteers, staff and students/trainees. Data will be collected one time with no follow up. Patient group: We will prospectively collect data using one instrument (camera) (SnapshotNIR, Kent Imaging, Calgary, Alberta, Canada). We will collect non-contact imaging data before surgeries, during surgeries (if feasible... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
08/06/2024
Locations: UT Southwestern Medical Center at Dallas, Dallas, Texas
Conditions: Diabetic Foot Ulcer
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Cancer Clinical Trials Financial Reimbursement Program
NCT05402033
Recruiting
To implement a Financial Reimbursement and Outreach Program at clinical sites within the Harold C. Simmons Comprehensive Cancer Center; and evaluate the impact of the program on clinical trial enrollment and demographics, as well as facilitators of and barriers to program participation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Cancer Clinical Trials
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A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies
NCT05780034
Recruiting
This clinical trial is evaluating a drug called AC676 in participants with Relapsed/Refractory B-cell Malignancies. The main goals of the study are to: * Identify the recommended dose of AC676 that can be given safely to participants * Evaluate the safety profile of AC676 * Evaluate the pharmacokinetics of AC676 * Evaluate the effectiveness of AC676
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Relapsed/Refractory B-cell Malignancies
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Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research
NCT04664192
Recruiting
A major goal of this protocol is to support biomarker studies in advanced lung diseases, lung transplantation care, and to improve our understanding of the effects of viral and other infectious exposures to outcomes in our lung transplant and ALD patient populations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Respiratory Failure, Interstitial Lung Disease, Lung Diseases
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Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis
NCT04891640
Recruiting
This randomized pragmatic trial will generate knowledge about strategies used to de-escalate tumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with sustained inactive disease and are treated at one of the 29 participating pediatric healthcare systems. This open label study will be conducted in the setting of routine clinical care and will compare the risk and timing of flare (Aim 1) and patients' lived experiences (Aim 2) across three arms.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
08/02/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Juvenile Spondyloarthritis
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Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma
NCT04301843
Recruiting
Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study in combination with etoposide for subjects with relapsed/refractory neuroblastoma.
Gender:
ALL
Ages:
31 years and below
Trial Updated:
08/02/2024
Locations: Children's Medical Center Dallas, Dallas, Texas
Conditions: Neuroblastoma
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Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation
NCT05917678
Recruiting
This study will examine how effective caregiver's repositioning strategies are in correcting an infant's deformational cranial shape, as well as the effectiveness of the use of a custom cranial remolding orthosis for treatment of deformational head shapes. Infants with torticollis will be concurrently enrolled in physical therapy treatment until the torticollis is resolved. A normal, unaffected population will be studied to compare typical growth to the growth of infants undergoing active treatm... Read More
Gender:
ALL
Ages:
Between 2 months and 3 months
Trial Updated:
08/01/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Deformational Plagiocephaly, Deformational Posterior Plagiocephaly, Brachycephaly, Torticollis, Congenital Muscular Torticollis
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A Clinical Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HF158K1 in Participants With HER-2 Positive or HER-2 Low Expression Advanced Solid Tumors
NCT05861895
Recruiting
HF158K1 is an investigational liposome form of doxorubicin hydrochloride, an anthracycline topoisomerase inhibitor, encapsulated by lipid membranes containing TL01, a HER2-directed Trastuzumab Fab fragment conjugated lipid.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Solid Tumors, Adult
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