There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Patch-free Occlusion Therapy
NCT05440448
Recruiting
The purpose of the study is to determine whether a patch-free occlusion therapy leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is associated with better adherence to the treatment.
Gender:
All
Ages:
Between 3 years and 10 years
Trial Updated:
06/13/2023
Locations: Retina Foundation, Dallas, Texas
Conditions: Amblyopia
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The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
NCT04091984
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: UT Southwestern, Dallas, Texas
Conditions: Kidney Transplant Rejection
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Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)
NCT04827238
Recruiting
The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics) post-TAVR.
Gender:
All
Ages:
All
Trial Updated:
06/06/2023
Locations: Baylor Scott & White, Dallas, Texas
Conditions: Aortic Stenosis, Aortic Valve Stenosis
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GCC19CART for Patients With Metastatic Colorectal Cancer
NCT05319314
Recruiting
Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Colorectal Cancer
Register for Updates
Suicide Treatment Alternatives for Teens
NCT04089254
Recruiting
Quasi-Randomized trial to compare inpatient care versus outpatient crisis intervention clinic. This study plans to enroll up to 1,000 participants across 4 sites in a 5 years period.
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
06/01/2023
Locations: UT Southwestern Medical Center/Children's Health, Dallas, Texas
Conditions: Suicidal Ideation
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SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma
NCT03546582
Recruiting
This phase II trial with a safety run-in component will evaluate whether the addition of pembrolizumab to Stereotactic Body Radiation Therapy (SBRT) re-irradiation will improve the progression-free survival for patients with recurrent or new second primary Head and Neck Squamous Cell Carcinoma (HNSCC).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/01/2023
Locations: University of Texas Southwestern, Dallas, Texas
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
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A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants
NCT05662215
Recruiting
Learn about the safety and tolerability of CK-3828136 after a single dose and multiple doses in healthy subjects. Find out how much CK-3828136 is in the blood after a single dose and multiple doses. Determine the effect different doses of CK-3828136 on the pumping function of the heart.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
05/24/2023
Locations: Labcorp Clinical Research Unit Inc., Dallas, Texas
Conditions: Healthy Participants
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Isatuximab as Upfront Therapy for the Treatment of High Risk AL Amyloidosis
NCT04754945
Recruiting
This phase I trial studies the side effects of isatuximab and to see how well it works in treating patients with high risk immunoglobulin light chain amyloidosis (AL amyloidosis). Isatuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: UT Southwestern, Dallas, Texas
Conditions: AL Amyloidosis
Register for Updates
Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency
NCT04565015
Recruiting
The purpose of this study is to evaluate the pharmacokinetics and safety of Immune Globulin Intravenous (Human) GC5107 in pediatric subjects with Primary Humoral Immunodeficiency (PHID).
Gender:
All
Ages:
Between 2 years and 16 years
Trial Updated:
05/15/2023
Locations: Allergy Partners of North Texas Research, Dallas, Texas
Conditions: Primary Immune Deficiency
Register for Updates
Risk Indicators of Sarcoidosis Evolution-Unified Protocol
NCT05567133
Recruiting
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
Gender:
All
Ages:
19 years and above
Trial Updated:
05/10/2023
Locations: UT Southwestern, Dallas, Texas
Conditions: Sarcoidosis, Pulmonary
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A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
NCT05866861
Recruiting
The main purpose of this study is to evaluate the safety and tolerability of CUG252 following multiple ascending doses in participants with Systemic Lupus Erythematosus (SLE).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/10/2023
Locations: Site 1006, Dallas, Texas
Conditions: Systemic Lupus Erythematosus, SLE (Systemic Lupus), Autoimmune
Register for Updates
Affect Treatment for Depression and Anxiety
NCT05203861
Recruiting
The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing reward sensitivity in individuals with low positive affect (a core feature of anhedonia) in the context of depression or anxiety. Target enrollment is 100 male and female participants with low positive affect and depression or anxiety and impaired functioning, between the ages of 18 and 65 years, who will be randomized to either Positive Aff... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2023
Locations: Southern Methodist University, Dallas, Texas
Conditions: Depression, Anxiety
Register for Updates