There are currently 1554 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Recruiting
An observational study of electronic patient data to compare diabetes medications and to determine which ones offer the best balance of risks and benefits.
Gender:
All
Ages:
30 years and above
Trial Updated:
06/16/2023
Locations: Baylor Scott & White, Dallas, Texas
Conditions: Diabetes Mellitus, Type 2
Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis
Recruiting
This is a clinical trial in patients with advanced hepatocellular carcinoma (HCC) and Child-Pugh Class B7 (CPB7) cirrhosis whose disease has progressed on at least 1st-line therapy. The trial will evaluate the efficacy and safety of namodenoson as compared to placebo.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/15/2023
Locations: Site 881, Dallas, Texas
Conditions: Hepatocellular Carcinoma, Cirrhosis
A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling
Recruiting
This is a Phase 1/2, multicenter, open-label trial of avapritinib in participants 2 to < 18 years of age with advanced relapsed/refractory (R/R) solid tumors, including central nervous system (CNS) tumors, that harbor a PDGFRA and/or KIT mutation (including non-synonymous point mutations, insertions, and deletions) or amplification, or DMG-H3K27a who have no available curative treatment options. This is a single-arm trial in which all participants will receive avapritinib. The study consists of... Read More
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
06/14/2023
Locations: Children's Medical Center, Dallas, Texas
Conditions: Solid Tumor, Unspecified, Child, Relapsed Solid Neoplasm, CNS Tumor
Binocular Amblyopia Treatment
Recruiting
To evaluate the effectiveness of enhanced binocular amblyopia treatments in achieving a more complete and stable recovery.
Gender:
All
Ages:
Between 4 years and 10 years
Trial Updated:
06/13/2023
Locations: Retina Foundation of the Southwest, Dallas, Texas
Conditions: Amblyopia
Asynchronous Movies for Amblyopia
Recruiting
The purpose of this study is to determine whether viewing asynchronous movies leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is associated with better adherence to treatment.
Gender:
All
Ages:
Between 3 years and 8 years
Trial Updated:
06/13/2023
Locations: Retina Foundation, Dallas, Texas
Conditions: Amblyopia
Patch-free Occlusion Therapy
Recruiting
The purpose of the study is to determine whether a patch-free occlusion therapy leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is associated with better adherence to the treatment.
Gender:
All
Ages:
Between 3 years and 10 years
Trial Updated:
06/13/2023
Locations: Retina Foundation, Dallas, Texas
Conditions: Amblyopia
The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: UT Southwestern, Dallas, Texas
Conditions: Kidney Transplant Rejection
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access
Recruiting
The CSP-2002 study will evaluate the safety and effectiveness of the InnAVasc arteriovenous graft (AVG) when implanted in and used for hemodialysis in participants suffering from end-stage renal failure (ESRD). The InnAVasc AVG is implanted and used similar to other standard-of-care dialysis grafts currently on the market. However, the InnAVasc AVG has been uniquely designed to potentially allow for immediate needle access (same day as implant surgery as opposed to 2-4 weeks of waiting), to pote... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
06/08/2023
Locations: Baylor Heart and Vascular, Dallas, Texas
Conditions: End Stage Renal Disease (ESRD), Kidney Failure, Chronic Renal Disease
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
Recruiting
The global objective of this study is to determine the mechanisms of exercise intolerance and dyspnea on exertion (DOE) in patients with HFpEF and based on this pathophysiology, test whether specific exercise training programs (whole body vs single leg) will result in improved exercise tolerance.
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
06/06/2023
Locations: The Institute for Exercise and Environmental Medicine, Dallas, Texas
Conditions: Heart Failure, Diastolic
Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)
Recruiting
The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics) post-TAVR.
Gender:
All
Ages:
All
Trial Updated:
06/06/2023
Locations: Baylor Scott & White, Dallas, Texas
Conditions: Aortic Stenosis, Aortic Valve Stenosis
Functional Assessment in Liver Transplantation
Recruiting
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive function. Subjects will again undergo assessments at every clinic visit through 12 months after transplant. Then, they will be followed annuall... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: Baylor Scott & White Health, Dallas, Texas
Conditions: End Stage Liver Disease
GCC19CART for Patients With Metastatic Colorectal Cancer
Recruiting
Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Colorectal Cancer