There are currently 1547 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
NCT04613921
Recruiting
Management of ACLF is mainly supportive. The poor outcomes lead physicians to consider liver transplantation as an option, even if controversial. In sicker recipients, LT results in immediate survival, but poor medium-term survival rates in some studies. The scarcity of deceased donors obliges to maximize LT success. Alternative strategies, as living-donor LT, should be explored. LDLT has impressive results in Eastern centers, but it is restrained in Western countries, due to potential life-thre... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/03/2023
Locations: Baylor College of Medicine (Scott & White), Dallas, Texas
Conditions: Liver Diseases, Liver Cirrhosis, Acute-On-Chronic Liver Failure, Liver Transplant; Complications
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Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
NCT03906435
Recruiting
This study is being done to see if outcomes for both a premature infant's parents and the infant born prematurely who have spent time in the neonatal intensive care unit (NICU) can be improved through parent cognitive behavioral therapy (CBT) sessions.
Gender:
All
Ages:
All
Trial Updated:
05/02/2023
Locations: Parkland Health & Hospital System, Dallas, Texas
Conditions: Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
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PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
All
Ages:
All
Trial Updated:
05/01/2023
Locations: Medical City Dallas Hospital, Dallas, Texas +1 locations
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
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Study of ORIC-944 in Patients With Metastatic Prostate Cancer
NCT05413421
Recruiting
The purpose of this study is to establish recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD) and preliminary antitumor activity of ORIC-944 in patients with metastatic prostate cancer.
Gender:
Male
Ages:
18 years and above
Trial Updated:
04/28/2023
Locations: Urology Clinics of North Texas, Dallas, Texas
Conditions: Metastatic Prostate Cancer, Neuroendocrine Prostate Cancer
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Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants
NCT00992303
Recruiting
RATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2023
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
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DBS of the SCC for the Treatment of Medically Refractory CLBP
NCT04085406
Recruiting
The purpose of this study is to evaluate the feasibility and preliminary efficacy of deep brain stimulation of the subgenual cingulate cortex for the treatment of chronic medically-refractory low back pain using a randomized double-blind crossover design.
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
04/22/2023
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Chronic Low-back Pain
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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
NCT04174157
Recruiting
Spinal muscular atrophy (SMA) is a neurogenetic disorder caused by a loss or mutation in the survival motor neuron 1 gene (SMN1) on chromosome 5q13, which leads to reduced SMN protein levels and a selective dysfunction of motor neurons. SMA is an autosomal recessive, early childhood disease with an incidence of 1:10,000 live births. SMA is the leading cause of infant mortality due to genetic diseases. Until recently, the mainstay of treatment for these patients was supportive medical care. Howe... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2023
Locations: Children's Health, Dallas, Texas
Conditions: Spinal Muscular Atrophy (SMA)
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Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)
NCT05268094
Recruiting
COMPASS is a prospective multicenter randomized interventional trial. Participants with ductal-dependent pulmonary blood flow will be randomized to receive either a systemic-to-pulmonary artery shunt or ductal artery stent. Block randomization will be performed by center and by single vs. two ventricle status. Participants will be followed through the first year of life.
Gender:
All
Ages:
Between 1 day and 30 days
Trial Updated:
04/12/2023
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Congenital Heart Disease in Children
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Prospective Evaluation of Treatment for Clubfoot
NCT02257229
Recruiting
Specific aim: To evaluate the outcome of infants who undergo one of two nonsurgical treatment interventions
Gender:
All
Ages:
18 years and below
Trial Updated:
04/10/2023
Locations: Texas Scottish Rite Hospital for Children, Dallas, Texas
Conditions: Clubfoot Deformity
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Screening for High Frequency Malignant Disease
NCT05117840
Recruiting
The SHIELD (Screening for High Frequency Malignant Disease) study is a prospective, observational, multi-site basket design trial without randomization. The primary objective of the study is to evaluate the sensitivity and specificity of a blood-based GuardantLUNAR-2 test to detect high frequency cancer in screen-relevant populations.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
04/10/2023
Locations: Southwest Family Medicine Associates, Dallas, Texas +1 locations
Conditions: Lung Cancer
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A Study of Surgical Interventions in Fistulizing Conditions
NCT04940611
Recruiting
In this study, participants with complex fistulizing conditions will be treated with surgical interventions according to their clinic's standard practice. The aim of the study is to generate real-world evidence on standard of care for surgical interventions and related outcomes when treating complex fistulizing conditions. The study sponsor will not be involved in how participants are treated but will provide instructions on how the clinics will record what happens during the study.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/04/2023
Locations: Baylor Research Institute, Dallas, Texas
Conditions: Crohns Disease, Fistula, Rectovaginal Fistula, Complex Perianal Fistula, Complex Cryptoglandular Fistula
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Early Routine Bowel Preparation for Suspected Acute Diverticular Bleeding
NCT05170945
Recruiting
This investigation will utilize both a five-year retrospective analysis and a two-year prospective investigation. Variables including age; gender; presence of anticoagulation medication; hospital length of stay; total transfused red blood cell units; presence of heart failure, chronic kidney disease, or lung disease; history of diverticular disease; whether colonoscopy was performed; if therapeutic hemostasis was performed during colonoscopy; and information regarding prior colonoscopies in the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/30/2023
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Diverticular Bleeding
Register for Updates