Utah is currently home to 1240 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Salt Lake City, Murray, Ogden and West Jordan. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice
NCT05369832
Recruiting
The purpose of this study is to explore the safety, efficacy, effects on quality of life (QOL), and biomarker response of ozanimod in participants with moderate to severely active ulcerative colitis (UC) in clinical practice.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Ogden Clinic Gastrenterology - CAR, Ogden, Utah
Conditions: Colitis, Ulcerative
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A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)
NCT05201144
Recruiting
Congenital diaphragmatic hernia (CDH) occurs in approximately 1 in 3000 US live births, similar to the incidence seen within the Utah Birth Defects cohort. The diaphragmatic defect compromises lung growth and alters pulmonary vascular development. This is reflected postnatally as respiratory failure, pulmonary hypertension (PH) and overall cardiopulmonary dysfunction, particularly post-repair. Currently, optimal management of post-repair PH remains poorly investigated. Sildenafil citrate is a hi... Read More
Gender:
All
Ages:
All
Trial Updated:
05/06/2024
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Congenital Diaphragmatic Hernia, Pulmonary Hypertension
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High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia
NCT04774848
Recruiting
The purpose of this study is to conduct a prospective study of all congenital diaphragmatic hernia (CDH) neonates managed at the University of Utah newborn intensive care unit (NICU) and Primary Children's Hospital NICU that required mechanical ventilation at birth. As both high frequency jet ventilation (HFJV) and high frequency oscillatory ventilation (HFOV) are standard approaches to ventilatory support of all neonates including CDH, CDH infants will be randomized at the time of birth or admi... Read More
Gender:
All
Ages:
24 hours and below
Trial Updated:
05/06/2024
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Congenital Diaphragmatic Hernia
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Warfarin Patient Self-management Implementation in the US Healthcare System
NCT04766216
Recruiting
In the US, patients receiving warfarin therapy are rarely allowed to engage in patient self-management (PSM) which is less burdensome, less expensive, and safer than standard clinic-directed warfarin management. The long-term objective of our application is to improve the safety of ambulatory warfarin therapy through increasing the implementation of PSM.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Utah Thrombosis Center, Salt Lake City, Utah
Conditions: Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases
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Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
NCT03012529
Recruiting
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to o... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
05/06/2024
Locations: VA Salt Lake City Health Care System, Salt Lake City, UT, Salt Lake City, Utah
Conditions: Osteomyelitis, Diabetes, Amputation
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Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
NCT01099982
Recruiting
Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no inve... Read More
Gender:
All
Ages:
13 years and above
Trial Updated:
05/04/2024
Locations: Intermountain Medical Center, Murray, Utah
Conditions: Congestive Heart Failure
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A Study to Learn About the Study Medicine Sisunatovir in Adults With Respiratory Syncytial Virus (RSV) Infection
NCT06079320
Recruiting
The purpose of this study is to learn about the safety and effects of sisunatovir. Sisunatovir is studied for the possible treatment of Respiratory Syncytial Virus (RSV). RSV is a virus that causes lung infections with cold-like symptoms, but it can cause severe illness in some people. Sisunatovir is studied in adults: who are not admitted to the hospital and who have high chances of having a severe illness from RSV infection. This study is seeking participants who: Are confirmed to have RSV.... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Alpine Research Organization, Clinton, Utah
Conditions: Respiratory Syncytial Virus Infection
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A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
NCT06007690
Recruiting
The primary objective is to determine the safety and efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma (CM).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Retina Associates of Utah, Salt Lake City, Utah
Conditions: Choroidal Melanoma, Indeterminate Lesions, Uveal Melanoma, Ocular Melanoma
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CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
NCT05722418
Recruiting
This is a Phase 1 study to evaluate the safety of CB-011 (the study treatment), an allogeneic chimeric antigen receptor (CAR-T) cell therapy that targets the B cell maturation antigen (BCMA), to determine the best dose of CB-011, and to assess the effectiveness of CB-011 in treating multiple myeloma that has come back (relapsed) or that is no longer responding to other treatment (refractory).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
Conditions: Relapsed/Refractory Multiple Myeloma
Register for Updates
Trial of Indication-Based Transfusion of Red Blood Cells in ECMO
NCT05405426
Recruiting
TITRE - Trial of Indication-based Transfusion of Red Blood Cells in ECMO, is a multicenter, prospective, randomized clinical trial. The overarching goal of TITRE is to determine whether restricting red blood cell (RBC) transfusion according to an indication-based strategy for those with bleeding and/or deficit of tissue oxygen delivery, compared with transfusion based on center-specific hemoglobin or hematocrit thresholds, can reduce organ dysfunction and improve later neurodevelopment in critic... Read More
Gender:
All
Ages:
Between 1 day and 6 years
Trial Updated:
05/03/2024
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Extracorporeal Membrane Oxygenation, Red Blood Cell Transfusion, Organ Failure, Multiple
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A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
NCT04808505
Recruiting
This is a Phase 3, open-label, multicenter study to evaluate the safety, efficacy, PK, PD, and immunogenicity of cipaglucosidase alfa/miglustat treatment in ERT-experienced and ERT-naïve pediatric subjects with IOPD.
Gender:
All
Ages:
17 years and below
Trial Updated:
05/03/2024
Locations: University of Utah, Clinical and Translational Sciences Institute, Salt Lake City, Utah
Conditions: Glycogen Storage Disease Type II Infantile Onset
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A First-in-Human Safety Trial of MTX-463
NCT06401213
Recruiting
A randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study to assess the safety, tolerability, and PK of single and multiple ascending doses of MTX-463 administered in healthy adults.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/02/2024
Locations: ICON, Salt Lake City, Utah
Conditions: Healthy
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