There are currently 334 clinical trials in Norfolk, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Hospital of The King's Daughters, Sentara Norfolk General Hospital, Virginia Oncology Associates and Eastern Virginia Medical School. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
NCT03460977
Recruiting
A Phase 1 Dose Escalation and Expanded Cohort Study Of PF-06821497 In The Treatment Of Adult Patients With Relapsed/Refractory Small Cell Lung Cancer (SCLC), Castration Resistant Prostate Cancer (CRPC) And Follicular Lymphoma (FL).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Virginia Oncology Associates, Norfolk, Virginia
Conditions: Small Cell Lung Cancer (SCLC), Follicular Lymphoma (FL), Castration Resistant Prostate Cancer (CRPC)
Register for Updates
Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)
NCT05986864
Recruiting
This is a phase 1/2 clinical study to evaluate the safety, preliminary efficacy, immunogenicity, and pharmacokinetic (PK) characteristics of SKG0106 in subjects with nAMD. Based on results from the phase 1 dose escalation study, the phase 2 expansion study will be conducted.
Gender:
All
Ages:
50 years and above
Trial Updated:
04/29/2024
Locations: Wagner Kapoor Research Institute, Norfolk, Virginia
Conditions: Neovascular Age-related Macular Degeneration
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ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
NCT05932615
Recruiting
The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System for treating patients with symptomatic, severe native aortic stenosis who are considered intermediate or low risk for surgical mortality.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Sentara Norfolk General Hospital, Norfolk, Virginia
Conditions: Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder
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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
NCT04889872
Recruiting
This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve systems in subjects with moderate, calcific aortic stenosis. Following completion of enrollment, subjects will be eligible for enrollment in the continued access phase of the trial.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/26/2024
Locations: Sentara Norfolk General Hospital, Norfolk, Virginia
Conditions: Aortic Stenosis, Calcific, Aortic Valve Stenosis
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Study of TDM-180935 in Atopic Dermatitis Patients
NCT06363461
Recruiting
Randomized, Vehicle-controlled, Parallel Group Study of TDM-180935 in Atopic Dermatitis Patients
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2024
Locations: Site 2, Norfolk, Virginia
Conditions: Atopic Dermatitis
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Cardiac Implantable Electronic Device (CIED) Research Study
NCT05061862
Recruiting
The study is designed to collect data on Cardiovascular Implantable Electronic Device (CIED) information, implant procedure details, and/or patient characteristics to support development of future CIED products and procedures.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2024
Locations: Sentara Norfolk General Hospital, Norfolk, Virginia
Conditions: Arrhythmias, Cardiac, Bradycardia, Tachycardia
Register for Updates
ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk
NCT05064553
Recruiting
The primary objective is to assess overall sensitivity and specificity of Oncoguard™ Liver for hepatocellular cancer (HCC) detection in a surveillance population.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2024
Locations: Digestive & Liver Disease Specialists, Norfolk, Virginia
Conditions: Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis, Liver Cancer
Register for Updates
Contraceptive Efficacy Study of Ovaprene
NCT06127199
Recruiting
This will be a multi-center, single arm, open-label study of Ovaprene, a non-hormonal intravaginal ring, to investigate the contraceptive effectiveness, safety and acceptability of Ovaprene.
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
04/24/2024
Locations: Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Contraception
Register for Updates
Early Detection of Breast Cancer in Women With Suspicious Mammograms
NCT03147430
Recruiting
This is a non-treatment study. It will not involve the use of any investigational drug or device. Potential participants will be enrolled through direct contact with collaborating clinical sites when the patient's annual 3D mammogram report yields a BIRADS rating of 4-5. The clinical Investigators or a member of their staff will conduct consent discussion once a suspicious mammogram report is identified or if a patient is referred for imaging of a suspicious area in the breast. After consenting... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Sentara Norfolk General Breast Center, Norfolk, Virginia
Conditions: Breast Cancer
Register for Updates
A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer
NCT05630183
Recruiting
The goal of this clinical trial is to test if the addition of botensilimab to standard chemotherapy improves the efficacy compared to just chemotherapy alone in participants with metastatic pancreatic cancer. One group of participants will only receive chemotherapy while a second group of participants will receive botensilimab and chemotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Virginia Oncology Associates - Brock Cancer Center, Norfolk, Virginia
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Register for Updates
Safety and Efficacy of VDMN-21 Patch in Subjects With Common Warts
NCT05799157
Recruiting
This Phase 2 study has been designed to determine the safety and efficacy of repeated treatment sessions of VDMN-21 patch at two dose strengths as compared to a matched vehicle control patch in subjects with verruca vulgaris
Gender:
All
Ages:
Between 12 years and 65 years
Trial Updated:
04/23/2024
Locations: Site 14, Norfolk, Virginia
Conditions: Verruca Vulgaris, Warts, Common Wart
Register for Updates
Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea
NCT04801771
Recruiting
This study is a prospective, single-arm study conducted under a common implant and follow-up protocol. The objective will be to follow fifty-seven (57) adolescents and young adults (10-21 years of age), with Down syndrome, moderate to severe sleep apnea, and post-adenotonsillectomy, for 12 months after undergoing implant of the Inspire Upper Airway Stimulation (UAS) System. The study is being conducted in order to evaluate objective change in cognition and expressive language after implant and t... Read More
Gender:
All
Ages:
Between 10 years and 21 years
Trial Updated:
04/19/2024
Locations: Children's Hospital of the King's Daughters/East Virginia Medical School, Norfolk, Virginia
Conditions: Down Syndrome, Obstructive Sleep Apnea
Register for Updates