West Virginia is currently home to 338 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Morgantown, Charleston, Huntington and Wheeling. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
NCT05535894
Recruiting
This study aims to evaluate the EUS-RFA in terms of efficacy for pain management and improvement in quality-of-life parameters for patients with advanced inoperable pancreatic cancer. The primary objectives of this study are to 1) evaluate the utility of EUS-RFA for pain control and improvement in quality-of-life parameters for patients with advanced pancreatic cancer; 2) to measure the reduction of analgesic medications' requirements in patients affected by inoperable pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Shailendra Singh, Morgantown, West Virginia
Conditions: Pancreatic Cancer
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The Effect of Blood on the PC Ratio During Pregnancy
NCT05434845
Recruiting
This study will examine the effect if blood on the the protein to creatine (PC) ratio in pregnant patients by adding blood to urine samples.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
09/06/2022
Locations: Marshall University School of Medicine, Huntington, West Virginia
Conditions: Proteinuria in Pregnancy
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Optimizing Beta Blocker Dosage in Women While Using the Wearable Cardioverter Defibrillator
NCT04504188
Recruiting
The primary objective of this pilot study is to document the percentage achievement in effective HR control (average nighttime HR < 70 bpm) during WCD use in a cohort of female patients with cardiomyopathy in an outpatient setting using continuous heart rate (HR) trends data from the WCD to optimize BB/ivabradine dosage, as compared to a prior historical control.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/12/2022
Locations: CAMC, Charleston, West Virginia
Conditions: Cardiomyopathies, Heart Failure
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Pioglitazone Therapy Targeting Fatigue in Breast Cancer
NCT05013255
Recruiting
The goal of this project is to evaluate the therapeutic potential of pioglitazone (PIO) to target underlying mechanisms that promote muscle fatigue in patients with breast cancer. This represents an off-label use of this compound, both in terms of the patient population and the clinical phenotype targeted. The central research hypothesis of this study is that daily pioglitazone will restore transcriptional downregulation of pathways within skeletal that promote fatigue.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/11/2022
Locations: West Virginia University Cancer Institute, Morgantown, West Virginia
Conditions: Breast Cancer, Muscle Fatigue
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Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)
NCT04209543
Recruiting
This is a two-part study designed to evaluate the effect of Estetrol (E4) 15 or 20 mg, or placebo on the severity and frequency of vasomotor symptoms (VMS) (Efficacy Study Part) and the safety of E4 20 mg (Endometrial and General Safety Study Part)
Gender:
Female
Ages:
Between 40 years and 65 years
Trial Updated:
05/09/2022
Locations: Exemplar Research Inc, Morgantown, West Virginia
Conditions: Vasomotor Symptoms, Menopausal Symptoms
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Use of Transmucosal Ketamine in Post Stroke Depression
NCT04876066
Recruiting
Studies have shown that ketamine is very effective and has a quick onset in treatment of depression. Most of these studies used intravenous ketamine in an inpatient setting and there are no large trials examining its use in Post Stroke Depression (PSD). There have been only few studies that have used other routes of administration (i.e., oral, transmucosal, intranasal, intramuscular) of ketamine which provided symptom relief for depression. The purpose of this study is to assess the effectivenes... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/28/2022
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: Post-stroke Depression
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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033
Recruiting
The study is a multi-center, un-blinded, randomized control study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2022
Locations: West Virginia University Medicine, Morgantown, West Virginia
Conditions: Locally Advanced Pancreatic Cancer
Register for Updates
Longitudinal Performance of Epi proColon
NCT03218423
Recruiting
This study will evaluate longitudinal performance of Epi proColon with respect to test positivity, longitudinal adherence to Epi proColon screening, adherence to follow-up colonoscopy and diagnostic yield, as well as assay failure rates.
Gender:
All
Ages:
Between 50 years and 74 years
Trial Updated:
10/29/2021
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Colorectal Cancer, Colorectal Neoplasms
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Implementation of GLA:D Program in West Virginians With Osteoarthritis of the Knee
NCT04857879
Recruiting
This study will examine feasibility of implementing Good Life with Osteoarthritis in Denmark (GLA:D) program in West Virginians with osteoarthritis of the knee
Gender:
All
Ages:
Between 45 years and 90 years
Trial Updated:
08/30/2021
Locations: School of Physical Therapy, Marshall University, Huntington, West Virginia
Conditions: Osteoarthritis, Knee
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Huntington, West Virginia
Conditions: Ulcerative Colitis
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Convalescent Plasma Collection and Treatment in Pediatrics and Adults
NCT04376034
Recruiting
This is a prospective study, involving contacting potential plasma donors and the use of their plasma to help fight off infections of those suffering from COVID19 in accordance to collection guidelines for plasma and FDA IND requirement. This study will include up to 240 participants potentially receiving convalescent plasma and up to 1000 potential donors. There are 3 basic arms to the study: mild, moderate and severe/critical severity. All 3 severity groups are eligible for enrollment, but mi... Read More
Gender:
All
Ages:
31 days and above
Trial Updated:
05/01/2020
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: COVID19, Coronavirus Infection, Coronavirus, Virus Diseases, RNA Virus Infections
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Caris Biorepository Research Protocol
NCT01499394
Recruiting
The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/21/2020
Locations: CAMC Clinical Trials, Charleston, West Virginia
Conditions: Cancer
Register for Updates