Oregon is currently home to 1216 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
NCT05237258
Recruiting
This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
03/12/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Relapsed Adult AML, Primary Refractory Acute Myeloid Leukemia, High Risk Acute Myeloid Leukemia
Register for Updates
Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment
NCT04880473
Recruiting
PrevisEA is a noninvasive, disposable device that uses audio spectral analysis of sounds produced by the gastrointestinal tract to predict gastrointestinal impairment (GII). GII is most commonly associated with postoperative ileus (POI), but could be the result of other causes, such as early postoperative bowel obstruction. GII is defined as failure of successful early oral re-feeding in a subject undergoing major abdominal surgery. For subjects who are allowed to resume a diet during the first... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
03/11/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Gastrointestinal Complication
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Avenir Complete Post-Market Clinical Follow-Up Study
NCT04731077
Recruiting
The main objectives of this study are to confirm the long-term safety, performance and clinical benefits the Avenir Complete femoral stem and its instrumentation when used in primary total, hemi, and revision hip arthroplasty.
Gender:
All
Ages:
20 years and above
Trial Updated:
03/08/2024
Locations: Orthopedic & Fracture Clinic, PC, Portland, Oregon
Conditions: Osteoarthritis, Hip, Avascular Necrosis of Hip, Avascular Necrosis of the Femoral Head, Post-traumatic; Arthrosis
Register for Updates
ERP to Improve Functioning in Veterans With OCD
NCT05240924
Recruiting
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: VA Roseburg Healthcare System, Roseburg, OR, Roseburg, Oregon
Conditions: Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
Register for Updates
Study of the Safety and Neuroprotective Capacity of Scp776 in Acute Ischemic Stroke
NCT05585606
Recruiting
A Randomized, Placebo-Controlled, Double-Blind, Multicenter Study of the Safety and Neuroprotective Capacity of Scp776 in Subjects Undergoing Endovascular Thrombectomy for Acute Ischemic Stroke
Gender:
All
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Providence Portland Medical Center, Portland, Oregon
Conditions: Acute Ischemic Stroke (AIS)
Register for Updates
Dermal Allograft Augmentation of Large and Massive Rotator Cuff Tears
NCT05981833
Recruiting
The purpose of this study is to compare postoperative healing of large and massive rotator cuff tears with preoperative MRI confirmed fatty infiltration stage II and higher repaired with or without dermal allograft augmentation (DAA).
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
03/04/2024
Locations: Southern Oregon Orthopedics Research Foundation, Medford, Oregon
Conditions: Full-thickness Rotator Cuff Tear
Register for Updates
Trauma Resuscitation With Low-Titer Group O Whole Blood or Products
NCT05638581
Recruiting
The goal of this clinical trial is to compare the effectiveness of unseparated whole blood (referred to as Low-Titer Group O Whole Blood) and the separate components of whole blood (including red cells, plasma, platelets, and cryoprecipitate) in critically injured patients who require large-volume blood transfusions.
Gender:
All
Ages:
15 years and above
Trial Updated:
02/29/2024
Locations: Oregon Health and Sciences University Hospital, Portland, Oregon
Conditions: Wounds and Injuries, Shock, Hemorrhagic
Register for Updates
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
NCT03500328
Recruiting
FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) target the relapsing phase of MS but have minimal impact once the progressive phase has begun. It is unclear if, in the relapsing phase, there is an advantage of early aggressive therapy with respect to preventing long-term disability. The infectious risks and other complications associated with higher-efficacy treatments highlight the need to quantify their effectiveness in preventing disability. The TRaditional versus Ear... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
02/28/2024
Locations: Providence Health and Services - Oregon, Portland, Oregon
Conditions: Multiple Sclerosis, Relapsing-Remitting
Register for Updates
KEEP Connecting Kin
NCT06294392
Recruiting
The current study provides a unique opportunity to conduct a summative evaluation of the KEEP Connecting Kin (KEEP-CK) program by leveraging extant relationships with Oregon's Child Welfare System (CWS), Self-Sufficiency Program (SSP), and our community partners to address the needs of informal kinship families and the youth in their care. Specifically, a randomized "services-as-usual" (SAU) waitlist control design plus qualitative methods will be used to evaluate the immediate (post-interventio... Read More
Gender:
All
Ages:
Between 4 years and 18 years
Trial Updated:
02/27/2024
Locations: Oregon Center Learning Center, Eugene, Oregon
Conditions: Internalizing Behavior, Externalizing Behavior, Child Permanency, Parenting, Parent Stress, Service Utilization
Register for Updates
Transcranial Magnetic Stimulation in Progressive Supranuclear Palsy
NCT04468932
Recruiting
The objective of this proposal is to investigate the effect of non-invasive repetitive cerebellar transcranial magnetic stimulation (rTMS) on motor control in progressive supranuclear (PSP). The central hypothesis is that augmenting cerebellar inhibition via cerebellar rTMS will decrease postural instability in patients with PSP. We will use functional near infrared spectroscopy (fNIRS) to examine changes in motor and premotor cortical activity after cerebellar rTMS.
Gender:
All
Ages:
Between 40 years and 85 years
Trial Updated:
02/27/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Palsy Supranuclear, Supranuclear Palsy, Progressive
Register for Updates
Cobimetinib in Newly Diagnosed or HMA-treated CMML Patients With RAS Pathway Mutations
NCT04409639
Recruiting
This is an open-label, nonrandomized phase 2 trial to assess the efficacy of cobimetinib in RAS pathway activated CMML. All eligible patients will be treated daily with cobimetinib in 28-day cycles. Cobimetinib will be administered for three weeks followed by a one week break prior to the start of the following cycle. Patients will remain on study therapy until treatment discontinuation criteria is met.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Chronic Myelomonocytic Leukemia (CMML)
Register for Updates
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Huntington's Disease
Register for Updates